Functionalized coatings by electrospinning for anti-oxidant food packaging

The development of advanced formulations used for food packaging applications, which behave as protection or preservation materials and improve consumers’ health offers a route to reduced food wastage. The present study deals with investigations on the possibility of obtaining functionalized coatings by electrospinning of poly(ɛ-caprolactone), a synthetic biodegradable polymer together with vitamin E (α-tocopherol), selected as plant-based phenolic antioxidant. In this approach electrospinning allows the production of high surface area materials and thus offering an increased antioxidant activity. The electrospun fibres of poly(ɛ-caprolactone)/vitamin E were obtained, studied and their antioxidant properties were evaluated by measuring the fibre reactivity with 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical. The potential for extending the shelf-life of food products by using this approach is discussed

Functionalized coatings by electrospinning for anti-oxidant food packaging

The development of advanced formulations used for food packaging applications, which behave as protection or preservation materials and improve consumers’ health offers a route to reduced food wastage. The present study deals with investigations on the possibility of obtaining functionalized coatings by electrospinning of poly(ɛ-caprolactone), a synthetic biodegradable polymer together with vitamin E (α-tocopherol), selected as plant-based phenolic antioxidant. In this approach electrospinning allows the production of high surface area materials and thus offering an increased antioxidant activity. The electrospun fibres of poly(ɛ-caprolactone)/vitamin E were obtained, studied and their antioxidant properties were evaluated by measuring the fibre reactivity with 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical. The potential for extending the shelf-life of food products by using this approach is discussed

Electrospun chitosan-graft-poly (ɛ-caprolactone)/poly (ɛ-caprolactone) nanofibrous scaffolds for retinal tissue engineering

A promising therapy for retinal diseases is to employ biodegradable scaffolds to deliver retinal progenitor cells (RPCs) for repairing damaged or diseased retinal tissue. In the present study, cationic chitosan-graft-poly(ɛ-caprolactone)/polycaprolactone (CS-PCL/PCL) hybrid scaffolds were successfully prepared by electrospinning. Characterization of the obtained nanofibrous scaffolds indicated that zeta-potential, fiber diameter, and the content of amino groups on their surface were closely correlated with the amount of CS-PCL in CS-PCL/PCL scaffolds. To assess the cell–scaffold interaction, mice RPCs (mRPCs) were cultured on the electrospun scaffolds for 7 days. In-vitro proliferation assays revealed that mRPCs proliferated faster on the CS-PCL/PCL (20/80) scaffolds than the other electrospun scaffolds. Scanning electron microscopy and the real-time quantitative polymerase chain reaction results showed that mRPCs grown on CS-PCL/PCL (20/80) scaffolds were more likely to differentiate towards retinal neurons than those on PCL scaffolds. Taken together, these results suggest that CS-PCL/PCL(20/80) scaffolds have potential application in retinal tissue engineering

Polymeric materials with multiple crystalline phases: structure, morphology and crystallization

303 p.El objetivo de esta tesis doctoral es el análisis y la comparación de sistemas poliméricos multifásicos con al menos dos fases cristalizables, para diseñar y desarrollar nuevos materiales con propiedades mejoradas. La primera parte se centra en el estudio de mezclas PET/HDPE doblemente cristalinas con nanopartículas de titanio dióxido (tres tipos) y agentes compatibilizantes. La reducción de tamaño de partícula como consecuencia de la adición de las nanopartículas mejora las propiedades mecánicas.La segunda parte del trabajo consiste en el estudio de copolímeros de bloques multicristalinos. La adición de un tercer y cuarto bloque cristalino hace el análisis mucho más desafiante, pero se han identificado las cristalizaciones de todos los bloques en: terpolímeros PE-b-PEO-b-PLLA y PE-b-PCL-b-PLLA, y tetrapolímeros PE-b-PEO-b-PCL-b-PLLA y sus correspondientes terpolímeros (PE-b-PEO-b-PCL) y demás precursores (PE-b-PEO y PE). El efecto de la velocidad de enfriamiento (20 vs. 1 ºC/min) en los terpolímeros PE-b-PEO-b-PLLA y PE-b-PCL-b-PLLA hace variar la secuencia de cristalización, siendo a20 ºC/min el bloque de PE el primero en cristalizar, mientras que a 1 ºC/min la cristalización comienza con el bloque de PLLA, finalizando en todos los casos con los bloques de PEO o PCL, lo que dará lugar a distintas morfologías y propiedades mecánicas. El estudio de los tetrapolímeros (PE-b-PEO-b-PCL-b-PLLA) y sus terpolímeros precursores (PE-b-PEO-b-PCL) mediante DSC, SAXS/WAXS y PLOM demuestra su naturaleza triple- y tetra- cristalina, siguiendo las secuencias de cristalización e identificando esferulitas triple- y tetracristalinas

Preparation of composite materials based on poly-ɛ-caprolactone and hydroxyapatite by methods of mechanical mixing and in situ

In this investigation composite materials based on poly-ɛ-caprolactone and hydroxyapatite using mechanical mixing an

Characterization of hydroxyapatite/polypyrrole/poly (caprolactone) based solvent cast thin films

This study addressed the fabrication of thin films composed of Polypyrrole (PPy), hydroxyapatite (HA) and poly (ε-caprolactone) (PCL) via solvent casting method. The polymer and composite films were subsequently characterized in terms of morphology, wettability and water uptake properties using different techniques. The characterization of the thin films were determined using a Scanning Electron Microscope (SEM), Energy Dispersive X-ray (EDX), water contact angle and water uptake. The addition of HA and PPy reduced the hydrophobic properties of PCL in the thin films. An energy dispersive x-ray (EDX) analysis supported the existence of HA in composite thin films. Water uptake of PCL thin film was lower than HA/PCL and HA/PPy/PCL composite thin films. © 2006-2016 Asian Research Publishing Network (ARPN)

Electrospun Nanofibers for Neural Tissue Engineering

Biodegradable nanofibers produced by electrospinning represent a new class of promising scaffolds to support nerve regeneration. We begin with a brief discussion on electrospinning of nanofibers and methods for controlling the structure, porosity, and alignment of the electrospun nanofibers. The methods include control of the nanoscale morphology and microscale alignment for the nanofibers, as well as the fabrication of macroscale, three-dimensional tubular structures. We then highlight recent studies that utilize electrospun nanofibers to manipulate biological processes relevant to nervous tissue regeneration, including stem cell differentiation, guidance of neurite extension, and peripheral nerve injury treatments. The main objective of this feature article is to provide valuable insights into methods for investigating the mechanisms of neurite growth on novel nanofibrous scaffolds and optimization of the nanofiber scaffolds and conduits for repairing peripheral nerve injuries

LONG CHAIN POLYMERIC CARBOHYDRATE DEPENDENT NANOCOMPOSITES IN TISSUE ENGINEERING

The use of nanomedicine has increased enormously, especially in the field of gene delivery and targeted drug delivery. The objective of current review to identify long-chain polymeric carbohydrate dependent nano-composites in tissue engineering such gellan gum incorporated TiO2 nanotubes, Poly(vinyl) alcohol-gellan gum-based nanofiber, cross-linked gellan/pva nanofibers, nanocellulose reinforced gellan-gum hydrogels, dextran and sol-gel derived bioactive glass-ceramic nanoparticles, aminated β-cyclodextrin-modified-carboxylated magnetic cobalt/nanocellulose composite, chitosan-chitin nanocrystal composite scaffolds, sodium alginate-xanthan gum-based nano-composite scaffolds, nano-hydroxyapatite  pullulan/dextran polysaccharide composite, chitosan/carbon nanofibers scaffolds, nano-bio composite scaffold of chitosan–gelatin–alginate–hydroxyapatite, alginate/gelatin scaffolds with homogeneous nano apatite coating,nano-hydroxyapatite-alginate-gelatinmicrocapsule, poly(ε-caprolactone)/keratin nano fibrousmats, keratin nanoparticles-coating electrospun pva nanofiber, nano-hydroxyapatite/chitosan/chondroitin sulfate/hyaluronic acid and chitosan/chondroitin sulfate/nano-bioglass. The current review has identified a list of medicinal herbs that have been incorporated into long chain polymeric carbohydrate-based nano-composites.                    Peer Review History: Received 15 July 2020; Revised 13 August; Accepted 28 August, Available online 15 September 2020 Academic Editor: Essam Mohamed Eissa, Beni-Suef University, Egypt, [email protected] UJPR follows the most transparent and toughest ‘Advanced OPEN peer review’ system. The identity of the authors and, reviewers will be known to each other. This transparent process will help to eradicate any possible malicious/purposeful interference by any person (publishing staff, reviewer, editor, author, etc) during peer review. As a result of this unique system, all reviewers will get their due recognition and respect, once their names are published in the papers. We expect that, by publishing peer review reports with published papers, will be helpful to many authors for drafting their article according to the specifications. Auhors will remove any error of their article and they will improve their article(s) according to the previous reports displayed with published article(s). The main purpose of it is ‘to improve the quality of a candidate manuscript’. Our reviewers check the ‘strength and weakness of a manuscript honestly’. There will increase in the perfection, and transparency. Received file:                Reviewer's Comments: Average Peer review marks at initial stage: 6.5/10 Average Peer review marks at publication stage: 8.0/10 Reviewer(s) detail: Shahin Gavanji, World Academy of Medical Sciences, Iran,  [email protected] Dr. Asia Selman Abdullah, University of Basrah, Iraq, [email protected] Similar Articles: HEATING EFFECT ON PHYTOCHEMICAL AND PROXIMATE CONTENTS OF COOKED AQUEOUS EXTRACT OF PHASEOLUS VULGARIS (KIDNEY BEANS

A new approach for the preparation of functional pharmaceutical nanoparticles using glass capillary millifludic devices

Functional pharmaceuticals nanoparticles are solid carriers with a mean size of less than 1 μm, which are capable to dissolve, entrap, encapsulate or attach active ingredients (drug) to its nanoparticle matrix. In this study, a new approach for the formation of acetaminophen (PCM) encapsulated poly(ɛ-caprolactone) (PCL) nanoparticles with controllable size dependent has been performed in a glass capillary milifluidic device by nanoprecipitation (“diffusion-stranding”) method