The Pharmacological Potential of Mushrooms

This review describes pharmacologically active compounds from mushrooms. Compounds and complex substances with antimicrobial, antiviral, antitumor, antiallergic, immunomodulating, anti-inflammatory, antiatherogenic, hypoglycemic, hepatoprotective and central activities are covered, focusing on the review of recent literature. The production of mushrooms or mushroom compounds is discussed briefly

The pharmacological potential of hesperidin

287-300The modern scientific society has presently recognized flavonoids to be a unique class of therapeutic molecules due to their varied therapeutic properties. Of these, hesperidin, found along with vitamin C, has been explored for a number of pharmacological effects. Citrus and oranges possess hesperidin as one of the active constituents. Today, hesperidin has been well recognized for its beneficial effects on health. The present review highlights the current information and health-promoting effects of hesperidin. The review uncovers protective effects of hesperidin on functions and integrity of liver, kidney, heart, and age related memory impairment. Hesperidin demonstrated the antimicrobial, anticancer, antihypertensive and antiulcer effect. The present review focus on current information of hesperidin and its active metabolite hesperetin. Along with this, the chemotherapeutic potential of the same has also discussed

The pharmacological potential of hesperidin

The modern scientific society has presently recognized flavonoids to be a unique class of therapeutic molecules due to their varied therapeutic properties. Of these, hesperidin, found along with vitamin C, has been explored for a number of pharmacological effects. Citrus and oranges possess hesperidin as one of the active constituents. Today, hesperidin has been well recognized for its beneficial effects on health. The present review highlights the current information and health-promoting effects of hesperidin. The review uncovers protective effects of hesperidin on functions and integrity of liver, kidney, heart, and age related memory impairment. Hesperidin demonstrated the antimicrobial, anticancer, antihypertensive and antiulcer effect. The present review focus on current information of hesperidin and its active metabolite hesperetin. Along with this, the chemotherapeutic potential of the same has also discussed

Phytoalexins: Sources and Their Pharmacological Potential

Background: Plants are easily prone towards microbial infections on exposure to microorganisms and pathogens. In order to defense, plants produce low molecular weight secondary metabolites which were later known as “Phytoalexins”. These molecules have vast therapeutic potential also. Purpose: The purpose of this review is to explore the phytoalexins and their pharmacological effects.Methods: The data included from the articles were published from Web of Science, PubMed, Medline, Scopus, and Embase by using relevant keywords including plants possessing phytoalexins and their specific biological applications.Results: The review insights the potential of phytoalexins in various diseases and to explore phytoalexins applications in human health and disease control. Conclusions: On the basis of this review it may be concluded that phytoalexins have tremendous potential in the treatment and prevention of various life-threatening diseases like diabetes mellitus, cancer, brain damage, and heart attack

Pharmacological potential of green tomato glycoalcaloids: an overview

Glycoalkaloids are characteristic secondary metabolites in plants of the Solanaceae family. Although perceived as potentially toxic, these compounds display different bioactivities and pharmacological effects. The glycoalkaloids esculeoside A and tomatine (which comprises a junction of α-tomatine and dehydrotomatine) can be found in tomato plants. Structurally, dehydrotomatine differs from α-tomatine by having a double bond in the steroidal B ring of the aglycone; but both glycoalkaloids have the same tetrasaccharide (lycotetraose) side chain. Therefore, while α-tomatine has lycotetraose bonded to the aglycone tomatidine, dehydrotomatine has the side chain attached to the aglycone tomatidenol. Up to 500 mg/kg FW of tomatine can be found in unripe (green) tomatoes, levels that decrease with ripening (approximately 5 mg/kg FW in ripe red tomatoes) [1]. On the other hand, the content of esculeoside A, which is stored in ripe red tomatoes, is comparable to or higher than that of lycopene [2]. Thus, the levels of esculeoside A increase as the fruit matures, contrary to that observed for tomatine.To FCT for financial support through national funds FCT/MCTES to CIMO (UIDB/00690/2020); for the M. Añibarro-Ortega grant (2020.06297.BD) and the J. Pinela contract (CEECIND/01011/2018) through the individual scientific employment program-contract; and to ERDF through the Regional Operational Program North 2020, within the scope of the Project GreenHealth - Norte-01-0145-FEDER-000042..info:eu-repo/semantics/publishedVersio

PHARMACOLOGICAL POTENTIAL OF POLYHERBAL AYURVEDIC FORMULATIONS – A REVIEW

Ayurveda is an ancient traditional medical care system. The major aim of Ayurveda is to prevent unnecessary suffering and aiding healthy long life. Ayurveda incorporates natural constituents to make potential medicines that are believed to eliminate the root cause of the diseases. Forty-five thousand plant species are found in the subcontinent of India making it one of the largest biodiversity centers. In India alone, 15,000 medicinal plant species have been reported out of which 7500 species are used by the communities to cure different diseases. Ayurveda uses single or polyherbal for treatment. In these traditional medicine systems, various formulations are prepared one of which is fermented formulations, namely, arishtas and asavas. These formulations are prepared using a decoction of herbal drugs and contain self-generated alcohol. Fermented formulations are known for their stability and efficacy. Indian traditional literature states the usage of these formulations regularly with scientific validation strengthens one immunity and well-being. The current review focuses on Vidangarishta. Punarnavasava, Chandanasava, their preparations, therapeutics uses, and their toxic effects. A thorough understating of these formulations aids in standardizing Ayurveda as a marginalized medicine

PHYTOCHEMICAL AND PHARMACOLOGICAL POTENTIAL OF ANNONA SPECIES: A REVIEW

Herbal plants and phytogenic products have used for the treatment of various diseases from ancient times in the folklore medicine worldwide. Crude extracts from plants now play an important and valuable source for natural products that are used in the advancement of medicines against various diseases, for the improvement of pharmaceutical preparations and for novel bioscience research. One such plant genus is Annona, such as Annona muricata, Annona cherimola, Annona reticulata, Annona squamosa, and Annona senegalensis are some species widely cultivating in India and tropical regions of Asia for their edible fruits and medicinal values. These plants have been used for centuries as traditional folk medicine for the treatments of various diseases. The plants are considered to be a good source of vitamins, minerals, plant proteins, fibers, etc., as well as the plant is supposed to have many biological activities. This review describes the morphology and ecology of the plant, its ethnomedicinal uses, pharmacological activities, and phytoconstituents