fMRI-compatible rehabilitation hand device

BACKGROUND: Functional magnetic resonance imaging (fMRI) has been widely used in studying human brain functions and neurorehabilitation. In order to develop complex and well-controlled fMRI paradigms, interfaces that can precisely control and measure output force and kinematics of the movements in human subjects are needed. Optimized state-of-the-art fMRI methods, combined with magnetic resonance (MR) compatible robotic devices for rehabilitation, can assist therapists to quantify, monitor, and improve physical rehabilitation. To achieve this goal, robotic or mechatronic devices with actuators and sensors need to be introduced into an MR environment. The common standard mechanical parts can not be used in MR environment and MR compatibility has been a tough hurdle for device developers. METHODS: This paper presents the design, fabrication and preliminary testing of a novel, one degree of freedom, MR compatible, computer controlled, variable resistance hand device that may be used in brain MR imaging during hand grip rehabilitation. We named the device MR_CHIROD (Magnetic Resonance Compatible Smart Hand Interfaced Rehabilitation Device). A novel feature of the device is the use of Electro-Rheological Fluids (ERFs) to achieve tunable and controllable resistive force generation. ERFs are fluids that experience dramatic changes in rheological properties, such as viscosity or yield stress, in the presence of an electric field. The device consists of four major subsystems: a) an ERF based resistive element; b) a gearbox; c) two handles and d) two sensors, one optical encoder and one force sensor, to measure the patient induced motion and force. The smart hand device is designed to resist up to 50% of the maximum level of gripping force of a human hand and be controlled in real time. RESULTS: Laboratory tests of the device indicate that it was able to meet its design objective to resist up to approximately 50% of the maximum handgrip force. The detailed compatibility tests demonstrated that there is neither an effect from the MR environment on the ERF properties and performance of the sensors, nor significant degradation on MR images by the introduction of the MR_CHIROD in the MR scanner. CONCLUSION: The MR compatible hand device was built to aid in the study of brain function during generation of controllable and tunable force during handgrip exercising. The device was shown to be MR compatible. To the best of our knowledge, this is the first system that utilizes ERF in MR environment

Soft Gloves: A Review on Recent Developments in Actuation, Sensing, Control and Applications

Interest in soft gloves, both robotic and haptic, has enormously grown over the past decade, due to their inherent compliance, which makes them particularly suitable for direct interaction with the human hand. Robotic soft gloves have been developed for hand rehabilitation, for ADLs assistance, or sometimes for both. Haptic soft gloves may be applied in virtual reality (VR) applications or to give sensory feedback in combination with prostheses or to control robots. This paper presents an updated review of the state of the art of soft gloves, with a particular focus on actuation, sensing, and control, combined with a detailed analysis of the devices according to their application field. The review is organized on two levels: a prospective review allows the highlighting of the main trends in soft gloves development and applications, and an analytical review performs an in-depth analysis of the technical solutions developed and implemented in the revised scientific research. Additional minor evaluations integrate the analysis, such as a synthetic investigation of the main results in the clinical studies and trials referred in literature which involve soft gloves

Human Motor Control and the Design and Control of Backdriveable Actuators for Human-Robot Interaction

The design of the control and hardware systems for a robot intended for interaction with a human user can profit from a critical analysis of the human neuromotor system and human biomechanics. The primary observation to be made about the human control and ``hardware’’ systems is that they work well together, perhaps because they were designed for each other. Despite the limited force production and elasticity of muscle, and despite slow information transmission, the sensorimotor system is adept at an impressive range of motor behaviors. In this thesis I present three explorations on the manners in which the human and hardware systems work together, hoping to inform the design of robots suitable for human-robot interaction. First, I used the serial reaction time (SRT) task with cuing from lights and motorized keys to assess the relative contribution of visual and haptic stimuli to the formation of motor and perceptual memories. Motorized keys were used to deliver brief pulse-like displacements to the resting fingers, with the expectation that the proximity and similarity of these cues to the response motor actions (finger-activated key-presses) would strengthen the motor memory trace in particular. Error rate results demonstrate that haptic cues promote motor learning over perceptual learning. The second exploration involves the design of an actuator specialized for human-robot interaction. Like muscle, it features series elasticity and thus displays good backdrivability. The elasticity arises from the use of a compressible fluid while hinged rigid plates are used to convert fluid power into mechanical power. I also propose impedance control with dynamics compensation to further reduce the driving-point impedance. The controller is robust to all kinds of uncertainties. The third exploration involves human control in interaction with the environment. I propose a framework that accommodates delays and does not require an explicit model of the musculoskeletal system and environment. Instead, loads from the biomechanics and coupled environment are estimated using the relationship between the motor command and its responses. Delays inherent in sensory feedback are accommodated by taking the form of the Smith predictor. Agreements between simulation results and empirical movements suggests that the framework is viable.PhDMechanical EngineeringUniversity of Michigan, Horace H. Rackham School of Graduate Studieshttp://deepblue.lib.umich.edu/bitstream/2027.42/120675/1/gloryn_1.pd

Soft pneumatic actuators: a review of design, fabrication, modeling, sensing, control and applications

Soft robotics is a rapidly evolving field where robots are fabricated using highly deformable materials and usually follow a bioinspired design. Their high dexterity and safety make them ideal for applications such as gripping, locomotion, and biomedical devices, where the environment is highly dynamic and sensitive to physical interaction. Pneumatic actuation remains the dominant technology in soft robotics due to its low cost and mass, fast response time, and easy implementation. Given the significant number of publications in soft robotics over recent years, newcomers and even established researchers may have difficulty assessing the state of the art. To address this issue, this article summarizes the development of soft pneumatic actuators and robots up until the date of publication. The scope of this article includes the design, modeling, fabrication, actuation, characterization, sensing, control, and applications of soft robotic devices. In addition to a historical overview, there is a special emphasis on recent advances such as novel designs, differential simulators, analytical and numerical modeling methods, topology optimization, data-driven modeling and control methods, hardware control boards, and nonlinear estimation and control techniques. Finally, the capabilities and limitations of soft pneumatic actuators and robots are discussed and directions for future research are identified

Elbow exoskeleton mechanism for multistage poststroke rehabilitation.

More than three million people are suffering from stroke in England. The process of post-stroke rehabilitation consists of a series of biomechanical exercises- controlled joint movement in acute phase; external assistance in the mid phase; and variable levels of resistance in the last phase. Post-stroke rehabilitation performed by physiotherapist has many limitations including cost, time, repeatability and intensity of exercises. Although a large variety of arm exoskeletons have been developed in the last two decades to substitute the conventional exercises provided by physiotherapist, most of these systems have limitations with structural configuration, sensory data acquisition and control architecture. It is still difficult to facilitate multistage post-stroke rehabilitation to patients sited around hospital bed without expert intervention. To support this, a framework for elbow exoskeleton has been developed that is portable and has the potential to offer all three types of exercises (external force, assistive and resistive) in a single structure. The design enhances torque to weight ratio compared to joint based actuation systems. The structural lengths of the exoskeleton are determined based on the mean anthropometric parameters of healthy users and the lengths of upperarm and forearm are determined to fit a wide range of users. The operation of the exoskeleton is divided into three regions where each type of exercise can be served in a specific way depending on the requirements of users. Electric motor provides power in the first region of operation whereas spring based assistive force is used in the second region and spring based resistive force is applied in the third region. This design concept provides an engineering solution of integrating three phases of post-stroke exercises in a single device. With this strategy, the energy source is only used in the first region to power the motor whereas the other two modes of exercise can work on the stored energy of springs. All these operations are controlled by a single motor and the maximum torque of the motor required is only 5 Nm. However, due to mechanical advantage, the exoskeleton can provide the joint torque up to 10 Nm. To remove the dependency on biosensor, the exoskeleton has been designed with a hardware-based mechanism that can provide assistive and resistive force. All exoskeleton components are integrated into a microcontroller-based circuit for measuring three joint parameters (angle, velocity and torque) and for controlling exercises. A user-friendly, multi-purpose graphical interface has been developed for participants to control the mode of exercise and it can be managed manually or in automatic mode. To validate the conceptual design, a prototype of the exoskeleton has been developed and it has been tested with healthy subjects. The generated assistive torque can be varied up to 0.037 Nm whereas resistive torque can be varied up to 0.057 Nm. The mass of the exoskeleton is approximately 1.8 kg. Two comparative studies have been performed to assess the measurement accuracy of the exoskeleton. In the first study, data collected from two healthy participants after using the exoskeleton and Kinect sensor by keeping Kinect sensor as reference. The mean measurement errors in joint angle are within 5.18 % for participant 1 and 1.66% for participant 2; the errors in torque measurement are within 8.48% and 7.93% respectively. In the next study, the repeatability of joint measurement by exoskeleton is analysed. The exoskeleton has been used by three healthy users in two rotation cycles. It shows a strong correction (correlation coefficient: 0.99) between two consecutive joint angle measurements and standard deviation is calculated to determine the error margin which comes under acceptable range (maximum: 8.897). The research embodied in this thesis presents a design framework of a portable exoskeleton model for providing three modes of exercises, which could provide a potential solution for all stages of post- stroke rehabilitation

Design and control of a pneumatically driven MRI-compatible tele-operated haptic interface

This study presents methods for understanding, modeling and control of tele-operated pneumatic actuators for rehabilitation in Magnetic Resonance Imaging (MRI). Pneumatic actuators have excellent MRI-compatibility as opposed to conventional electro-mechanical systems; however, the actuator and the system drivers cannot be co-located due to the MRI-compatibility requirements. The actuators are driven via long transmission lines, which affect the system dynamics significantly. Methods provided in this work produced accurate pressure estimation and control by accounting for the pressure dynamics in the lines, which has been neglected by previous work in this area. The effectiveness of the presented modeling and control methods were demonstrated on tele-operation test setups. This research also includes the design of necessary system components for the developed algorithms. An MRI-compatible optical sensor was developed for force feedback and its design was analyzed for high precision. Directions and opportunities for future research are discussed.Ph.D

Designing LMPA-Based Smart Materials for Soft Robotics Applications

This doctoral research, Designing LMPA (Low Melting Point Alloy) Based Smart Materials for Soft Robotics Applications, includes the following topics: (1) Introduction; (2) Robust Bicontinuous Metal-Elastomer Foam Composites with Highly Tunable Mechanical Stiffness; (3) Actively Morphing Drone Wing Design Enabled by Smart Materials for Green Unmanned Aerial Vehicles; (4) Dynamically Tunable Friction via Subsurface Stiffness Modulation; (5) LMPA Wool Sponge Based Smart Materials with Tunable Electrical Conductivity and Tunable Mechanical Stiffness for Soft Robotics; and (6) Contributions and Future Work.Soft robots are developed to interact safely with environments. Smart composites with tunable properties have found use in many soft robotics applications including robotic manipulators, locomotors, and haptics. The purpose of this work is to develop new smart materials with tunable properties (most importantly, mechanical stiffness) upon external stimuli, and integrate these novel smart materials in relevant soft robots. Stiffness tunable composites developed in previous studies have many drawbacks. For example, there is not enough stiffness change, or they are not robust enough. Here, we explore soft robotic mechanisms integrating stiffness tunable materials and innovate smart materials as needed to develop better versions of such soft robotic mechanisms. First, we develop a bicontinuous metal-elastomer foam composites with highly tunable mechanical stiffness. Second, we design and fabricate an actively morphing drone wing enabled by this smart composite, which is used as smart joints in the drone wing. Third, we explore composite pad-like structures with dynamically tunable friction achieved via subsurface stiffness modulation (SSM). We demonstrate that when these composite structures are properly integrated into soft crawling robots, the differences in friction of the two ends of these robots through SSM can be used to generate translational locomotion for untethered crawling robots. Also, we further develop a new class of smart composite based on LMPA wool sponge with tunable electrical conductivity and tunable stiffness for soft robotics applications. The implications of these studies on novel smart materials design are also discussed

Optimization of Proprioceptive Stimulation Frequency and Movement Range for fMRI

For vision, audition and tactile sense, the optimal stimulus frequency for fMRI is somewhat known. For proprioception, i.e., the “movement sense”, however, the optimal frequency is unknown. We studied the effect of passive-finger-movement frequency on proprioceptive fMRI responses using a novel pneumatic-movement actuator. Eleven healthy right-handed volunteers participated in the study. The movement actuator passively moved the participant’s right index finger at frequencies of 0.3, 1, 3, 6, 9, or 12 Hz in a blocked design. A functional localizer was used to define regions-of-interest in SI and SII cortices. In addition, effect of movement range on the fMRI responses was tested in a separate session with 1, 3, 5, and 7 mm movement ranges at a fixed 2 Hz frequency. In primary somatosensory (SI) cortex, the responses were stronger at 3 Hz than at 0.3 Hz (p < 0.001) or 1 Hz (p < 0.05), and at ≥6 Hz than 0.3 Hz (p < 0.001 for frequencies ≥ 6 Hz). In secondary somatosensory (SII) cortex, all movements, except at 0.3 Hz, elicited significant responses of similar strength. In addition, 6, 9, and 12-Hz movements elicited a significant offset response in both SI and SII cortices (p < 0.001–0.05). SI cortex required a total stimulation duration of 4 min to elicit significant activations at the group-level whereas for SII cortex 1 min 20 s was sufficient. Increase in the movement range led to stronger responses in SI cortex, but not in SII cortex. Movements above 3 Hz elicited the strongest SI cortex responses, and increase in the movement range enhanced the response strength. We thus recommend that movements at 3–6 Hz with a movement range of 5 mm or higher to be used in future studies of proprioception. Our results are in-line with previous fMRI and PET studies using tactile or median nerve stimulation at different stimulation frequencies

Development of Finger ContracturePrevention System For Early Post StrokeRehabilitation

芝浦尾工業大学2016年

Biomechatronics: Harmonizing Mechatronic Systems with Human Beings

This eBook provides a comprehensive treatise on modern biomechatronic systems centred around human applications. A particular emphasis is given to exoskeleton designs for assistance and training with advanced interfaces in human-machine interaction. Some of these designs are validated with experimental results which the reader will find very informative as building-blocks for designing such systems. This eBook will be ideally suited to those researching in biomechatronic area with bio-feedback applications or those who are involved in high-end research on manmachine interfaces. This may also serve as a textbook for biomechatronic design at post-graduate level