Metabolomics, peptidomics and proteomics applications of capillary electrophoresis-mass spectrometry in Foodomics: A review

In the current post-genomic era, Foodomics has been defined as a discipline that studies food and nutrition through the application of advanced omics approaches. Foodomics involves the use of genomics, transcriptomics, epigenetics, proteomics, peptidomics, and/or metabolomics to investigate food quality, safety, traceability and bioactivity. In this context, capillary electrophoresis-mass spectrometry (CE-MS) has been applied mainly in food proteomics, peptidomics and metabolomics. The aim of this review work is to present an overview of the most recent developments and applications of CE-MS as analytical platform for Foodomics, covering the relevant works published from 2008 to 2012. The review provides also information about the integration of several omics approaches in the new Foodomics field. © 2013 Elsevier B.V.This work was supported by AGL2011-29857-C03-01 (Ministerio de Economía y Competitividad, Spain), and CSD2007-00063 FUN-C-FOOD (Programa CONSOLIDER, Ministerio de Educacion y Ciencia, Spain) projects. C.I. thanks the Ministerio de Ciencia e Innovación for her FPI pre-doctoral fellowship. M.C.-P. thanks the Ministerio de Ciencia e Innovación for her Juan de la Cierva contract (JCI-2009-05297).Peer Reviewe