3 research outputs found
Megalanthine, a Bioactive Sesquiterpenoid from Heliotropium megalanthum, its Degradation Products and their Bioactivities
11 pages, figures, and tables statisticsAbstract The new bioactive sesquiterpenoid (3R,6E)-
2,6,10-trimethyl-3-(3-p-hydroxyphenylpropanoyloxy)-
dodeca-6,11-diene-2,10-diol, named megalanthine, was
isolated from the resinous exudates of Heliotropium
megalanthum. The degradation products of this compound
were identified. Several plant-defensive properties (insecticidal,
antifungal, and phytotoxic) were evaluated after
obtaining positive results in a preliminary etiolated wheat
coleoptile bioassay. This bioassay showed the need to have
both the phenolic and sesquiterpene moieties of the natural
product present to achieve a biological effect. This result
was confirmed in phytotoxicity bioassays. Megalanthine
was ruled out as a significant plantâplant defense agent
because of its lack of stability. The positive results recorded
in the antifungal and antifeedant tests suggest, however,
that this chemical is relevant in several ecological interactions
involving H. megalanthum.Peer reviewe
Megalanthine, a Bioactive Sesquiterpenoid from Heliotropium megalanthum, its Degradation Products and their Bioactivities
The new bioactive sesquiterpenoid (3R,6E)-2,6,10-trimethyl-3-(3-p-hydroxyphenylpropanoyloxy)-dodeca-6,11-diene-2,10-diol, named megalanthine, was isolated from the resinous exudates of Heliotropium megalanthum. The degradation products of this compound were identified. Several plant-defensive properties (insecticidal, antifungal, and phytotoxic) were evaluated after obtaining positive results in a preliminary etiolated wheat coleoptile bioassay. This bioassay showed the need to have both the phenolic and sesquiterpene moieties of the natural product present to achieve a biological effect. This result was confirmed in phytotoxicity bioassays. Megalanthine was ruled out as a significant plant-plant defense agent because of its lack of stability. The positive results recorded in the antifungal and antifeedant tests suggest, however, that this chemical is relevant in several ecological interactions involving H. megalanthum