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Crustacean metamorphosis: an omics perspective
Este artĂculo contiene 14 páginas, 4 figuras.Metamorphosis involves a complex network
of genes that orchestrate a perfectly timed
reorganization of one body form to another. The
molecular pathways that start to unravel for an
increasing number of species show that there exists
great diversity among different species, as would be
expected by their wide range of life histories and
transformation strategies. The metamorphosis process
could account for a considerably high percentile of
transcribed sequences over a short period of time, with
the genome encoding for different life forms. Such
important changes in expression patterns for a high
number of genes pose a challenge for accurately assign
each gene to a function. Several key conserved factors
are consistently expressed and can be placed at the
center of metamorphosis, including the mechanisms
involving the molt hormone, 20 Hydroxy-Ecdysone,
and the juvenile hormone. Yet, many additional
factors are not characterized, remain unannotated, or
do not have a function assigned. This manuscript
provides several examples of how an integrated omics
approach can develop further insights into crustacean
metamorphosis and eventually lead to discovery of
key factors for metamorphosis.The current study was supported by the
Australian Research Council Discovery Project (DP160103320)
and the Marie Curie International Research Staff Exchange
Scheme Fellowship within the 7th European Community
Framework Programme (612296-DeNuGReC). FP
acknowledges the project CHALLENGEN (CTM2013-48163)
of the Spanish Government and a post-doctoral contract funded
by the Beatriu de Pinos Programme of the Generalitat de
Catalunya.Peer reviewe