Biometry Protocol

The purpose of this resource is to measure and classify the plant life at a Land Cover Site to help determine the MUC classification. Educational levels: Primary elementary, Middle school, High school, Intermediate elementary

A Conversation with Professor Tadeusz Cali\'{n}ski

Tadeusz Cali\'{n}ski was born in Pozna\'{n}, Poland in 1928. Despite the absence of formal secondary eduction for Poles during the Second World War, he entered the University of Pozna\'{n} in 1948, initially studying agronomy and in later years mathematics. From 1953 to 1988 he taught statistics, biometry and experimental design at the Agricultural University of Pozna\'{n}. During this period he founded and developed the Pozna\'{n} inter-university school of mathematical statistics and biometry, which has become one of the most important schools of this type in Poland and beyond. He has supervised 24 Ph.D. students, many of whom are currently professors at a variety of universities. He is now Professor Emeritus. Among many awards, in 1995 Professor Cali\'{n}ski received the Order of Polonia Restituta for his outstanding achievements in the fields of Education and Science. In 2012 the Polish Statistical Society awarded him The Jerzy Sp{\l}awa-Neyman Medal for his contribution to the development of research in statistics in Poland. Professor Cali\'{n}ski in addition has Doctoral Degrees honoris causa from the Agricultural University of Pozna\'{n} and the Warsaw University of Life Sciences. His research interests include mathematical statistics and biometry, with applications to agriculture, natural sciences, biology and genetics. He has published over 140 articles in scientific journals as well as, with Sanpei Kageyama, two important books on the randomization approach to the design and analysis of experiments. He has been extremely active and successful in initiating and contributing to fruitful international research cooperation between Polish statisticians and biometricians and their colleagues in various countries, particularly in the Netherlands, France, Italy, Great Britain, Germany, Japan and Portugal. The conversations in addition cover the history of biometry and experimental design in Poland and the early influence of British statisticians.Comment: Published at http://dx.doi.org/10.1214/15-STS522 in the Statistical Science (http://www.imstat.org/sts/) by the Institute of Mathematical Statistics (http://www.imstat.org

Quality of ultrasound biometry obtained by local health workers in a refugee camp on the Thai-Burmese border.

Objective: In a refugee camp on the Thai–Burmese border, accurate dating of pregnancy relies on ultrasound measurements obtained by locally trained health workers. The aim of this study was to substantiate the accuracy of fetal biometry measurements performed by locally trained health workers by comparing derived reference equations with those published for Asian and European hospitals. Methods: This prospective observational study included 1090 women who had a dating crown–rump length (CRL) scan and one study-appointed ultrasound biometry scan between 16 and 40 weeks of gestation. The average of two measurements of each of biparietal diameter, head circumference, abdominal circumference and femur length was used in a polynomial regression model for the mean and SD against gestational age (GA). The biometry equations obtained were compared with published equations of professional sonographers from Asian and European hospitals by evaluation of the SD and Z-scores of differences between models. Results: Reference equations of biometric parameters were found to fit cubic polynomial models. The observed SD values, for any given GA, of fetal biometric measurements obtained by locally trained health workers were lower than those previously reported by centers with professional sonographers. For nearly the entire GA range considered, the mean values of the Asian and European equations for all four biometric measurements were within the 90% expected range (mean ± 1.645 SD) of our equations. Conclusion: Locally trained health workers in a refugee camp on the Thai–Burmese border can obtain measurements that are associated with low SD values and within the normal limits of published Asian and European equations. The fact that the SD values were lower than in other studies may be explained by the use of the average of two measurements, CRL dating or motivation of the locally trained sonographer

Land Cover Site Selection

The purpose of the resource is to determine the major land cover type at a Land Cover Sample Site. Educational levels: Middle school, High school

Evidence for uteroplacental malperfusion in fetuses with major congenital heart defects.

AIMS: Fetuses affected by congenital heart defects (CHD) are considered to be at increased risk of fetal growth restriction and intrauterine demise. Whether these risks are a direct consequence of fetal CHD or a result of associated uteroplacental dysfunction is not evident from the data of recent studies. The aim of this study was to investigate the prevalence of uteroplacental dysfunction reflected by abnormal uterine artery Doppler indices and reduced fetal growth in CHD pregnancies. METHODS: This is a retrospective case-control study including singleton pregnancies referred for detailed fetal cardiac assessment subsequently diagnosed with or without CHD. Mid-trimester uterine artery Doppler assessment at 20-24 weeks as well as third trimester fetal biometry and arterial Doppler pulsatility indices (PI) were performed. All fetal biometry were converted into centiles and Doppler values to multiples of median (MoM) to adjust for physiological changes with gestation. RESULTS: The study included 811 pregnancies including 153 cases where the fetus was diagnosed with CHD. Mid-pregnancy uterine artery PI was significantly higher in women with fetal CHD compared to controls (0.90MoM vs 0.83MoM; p = 0.006). In the third trimester, median centiles for fetal head circumference (45.4 vs 57.07; p<0.001), abdominal circumference (51.17 vs 55.71; p = 0.014), estimated fetal weight (33.6 vs 56.7; p<0.001) and cerebroplacental ratio (CPR: 0.84MoM vs 0.95MoM; p<0.001) were significantly lower in fetuses with CHD compared to controls. The percentage of small for gestational age births <10th centile (24.0% vs 10.7%; <0.001) and low CPR <0.6MoM (11.7% vs 2.5%; p<0.001) were significantly higher in the fetal CHD cohort. CONCLUSIONS: Mid-pregnancy uterine artery resistance is increased and subsequent fetal biometry reduced in pregnancies with CHD fetuses. These findings suggest that fetal CHD are associated with uteroplacental dysfunction, secondary to impaired maternal uteroplacental perfusion resulting in relative fetal hypoxaemia and reduced fetal growth

Sample Site Selection and Set-Up

The purpose of this resource is to select 15 km x 15 km Land Cover Sample Sites. Educational levels: Primary elementary, Intermediate elementary, Primary elementary, Intermediate elementary

MULTIPLEXED OPTICAL COHERENCE TOMOGRAPHY (OCT) IMAGING SYSTEM

Implementations of systems and methods of multiplexed OCT systems are disclosed herein. The field of view (FOV) and/or the wavelength of multiple OCT systems may be multiplexed. In contexts where the human eye will be imaged, power safety limits constrain the signal-to-noise (SNR) and/or speed of the OCT imaging. For retinal imaging, near-infrared wavelengths of 800 nm - 1100 nm may be used. For non-retinal imaging, 1200 nm – 1800 nm may be more typical. In implementations of the disclosure, a wavelength and FOV multiplexed OCT system generates whole eye biometry. The whole eye biometry may be at a first wavelength (e.g. approximately 1060 nm) and a face-biometry may be at a second wavelength (e.g. approximately 1300 nm). The eye biometry systems may include eye or pupil tracking sub-systems and pupil steering elements. One or both eye biometry systems may be moveable to allow for different inter-pupillary distances

Dandy-Walker malformation: is the "tail sign" the key sign?

OBJECTIVE.To demonstrate the value of the "tail sign" in the assessment of Dandy-Walker Malformation (DWM). METHODS: A total of 31fetal MRI, performed before 24 weeks of gestation after second-line US examination between May 2013 and September 2014, were examined retrospectively. All MRI examinations were performed using a 1.5 Tesla magnet without maternal sedation. RESULTS: MRI diagnosed 15/31 cases of Dandy-Walker Malformation, 6/31 cases of vermian partial caudal agenesis, 2/31 of vermian hypoplasia, 4/31 of vermian malrotation, 2/31 of Walker-Warburg Syndrome, 1/31 of Blake pouch cyst, 1/31 of rhombencephalosynapsis. All data were compared with fetopsy results, Fetal MR after the 30th week or postnatal MRI; the follow up depended on the maternal decision to terminate or continue pregnancy. In our review study we found the presence of the "tail sign"; this sign was visible only in Dandy-Walker Malformation and Walker-Warburg Syndrome. CONCLUSION: The "tail sign" could be helpful in the difficult differential diagnosis between Dandy Walker, vermian malrotation, vermian hypoplasia and vermian partial agenesis