4 research outputs found

    The representative COVID-19 cohort Munich (KoCo19): from the beginning of the pandemic to the Delta virus variant

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    Le Gleut R, Plank M, Pütz P, et al. The representative COVID-19 cohort Munich (KoCo19): from the beginning of the pandemic to the Delta virus variant. BMC Infectious Diseases. 2023;23(1): 466.**Background** Population-based serological studies allow to estimate prevalence of SARS-CoV-2 infections despite a substantial number of mild or asymptomatic disease courses. This became even more relevant for decision making after vaccination started. The KoCo19 cohort tracks the pandemic progress in the Munich general population for over two years, setting it apart in Europe. **Methods** Recruitment occurred during the initial pandemic wave, including 5313 participants above 13 years from private households in Munich. Four follow-ups were held at crucial times of the pandemic, with response rates of at least 70%. Participants filled questionnaires on socio-demographics and potential risk factors of infection. From Follow-up 2, information on SARS-CoV-2 vaccination was added. SARS-CoV-2 antibody status was measured using the Roche Elecsys® Anti-SARS-CoV-2 anti-N assay (indicating previous infection) and the Roche Elecsys® Anti-SARS-CoV-2 anti-S assay (indicating previous infection and/or vaccination). This allowed us to distinguish between sources of acquired antibodies. **Results** The SARS-CoV-2 estimated cumulative sero-prevalence increased from 1.6% (1.1-2.1%) in May 2020 to 14.5% (12.7-16.2%) in November 2021. Underreporting with respect to official numbers fluctuated with testing policies and capacities, becoming a factor of more than two during the second half of 2021. Simultaneously, the vaccination campaign against the SARS-CoV-2 virus increased the percentage of the Munich population having antibodies, with 86.8% (85.5-87.9%) having developed anti-S and/or anti-N in November 2021. Incidence rates for infections after (BTI) and without previous vaccination (INS) differed (ratio INS/BTI of 2.1, 0.7-3.6). However, the prevalence of infections was higher in the non-vaccinated population than in the vaccinated one. Considering the whole follow-up time, being born outside Germany, working in a high-risk job and living area per inhabitant were identified as risk factors for infection, while other socio-demographic and health-related variables were not. Although we obtained significant within-household clustering of SARS-CoV-2 cases, no further geospatial clustering was found. **Conclusions** Vaccination increased the coverage of the Munich population presenting SARS-CoV-2 antibodies, but breakthrough infections contribute to community spread. As underreporting stays relevant over time, infections can go undetected, so non-pharmaceutical measures are crucial, particularly for highly contagious strains like Omicron

    Brincando com o patrim├┤nio no Museu do Doce

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    Este trabalho se prop├Áe a analisar o conjunto de atividades intitulado A Turma do Quindim, realizado pelo LEP, (Laborat├│rio de Educa├ž├úo para o Patrim├┤nio), laborat├│rio vinculado ao curso de Museologia da UFPel que se dedica ao desenvolvimento de jogos e a├ž├Áes educativas relacionados ao patrim├┤nio. O conjunto ├ę composto por um Livro de atividades, um Jogo da mem├│ria dos doces, um Jogo do doce (jogo da velha) e por uma dramatiza├ž├úo com fantoches. Estes jogos e atividades l├║dicas foram utilizados pela equipe do LEP, formada por alunos do Curso de Museologia, em a├ž├Áes educativas no Museu do Doce, nos anos de 2017 e 2018. Estas a├ž├Áes foram desenvolvidas no museu com o objetivo de possibilitar uma troca de conhecimento referente ao Patrim├┤nio imaterial do doce. Estes jogos e atividades foram implementados para propiciar uma participa├ž├úo da crian├ža com o patrim├┤nio cultural no museu. O fundamento da a├ž├úo educativa ├ę a rela├ž├úo entre o acervo e o p├║blico que o visita, atuando por meio de est├şmulos capazes de estabelecer di├ílogos com os visitantes e facilitando a apreens├úo pelo p├║blico, isto ├ę, gerando o respeito e valoriza├ž├úo do patrim├┤nio cultural.Sem bols

    A new species of Acanthaspidia Stebbing, 1898 (Isopoda, Asellota, Acanthaspidiidae) from the bathyal Weddell Sea (Southern Ocean)

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    A new acanthaspidiid species, Acanthaspidia matsi sp. nov., is described from the Powell Basin slope (Weddell Sea, Southern Ocean). Specimens of the new species were collected during the expedition ANDEEP III on board RV Polarstern in March 2005. The new species most closely resembles Acanthaspidia typhlops (G. O. Sars, 1879), Acanthaspidia natalensis (Kensley, 1977) andAcanthaspidia bifurcatoides Kussakin & Vasina, 1982, but can be distinguished from all these species by the following characters: rostrum strongly trifid (tips 0.4 times rostrum length); pereonites 1, 3ÔÇô4 and 6 with 2 mid-dorsal spines; pleotelson spinulated, with 2 robust mid-dorsal spines. Systematic difficulties to distinguish the genera Acanthaspidia Stebbing, 1898 and Ianthopsis Beddard, 1886 are discussed and a key to all species in the genus Acanthaspidia is provided