3,222 research outputs found

    CEPC Technical Design Report -- Accelerator

    No full text
    International audienceThe Circular Electron Positron Collider (CEPC) is a large scientific project initiated and hosted by China, fostered through extensive collaboration with international partners. The complex comprises four accelerators: a 30 GeV Linac, a 1.1 GeV Damping Ring, a Booster capable of achieving energies up to 180 GeV, and a Collider operating at varying energy modes (Z, W, H, and ttbar). The Linac and Damping Ring are situated on the surface, while the Booster and Collider are housed in a 100 km circumference underground tunnel, strategically accommodating future expansion with provisions for a Super Proton Proton Collider (SPPC). The CEPC primarily serves as a Higgs factory. In its baseline design with synchrotron radiation (SR) power of 30 MW per beam, it can achieve a luminosity of 5e34 /cm^2/s^1, resulting in an integrated luminosity of 13 /ab for two interaction points over a decade, producing 2.6 million Higgs bosons. Increasing the SR power to 50 MW per beam expands the CEPC's capability to generate 4.3 million Higgs bosons, facilitating precise measurements of Higgs coupling at sub-percent levels, exceeding the precision expected from the HL-LHC by an order of magnitude. This Technical Design Report (TDR) follows the Preliminary Conceptual Design Report (Pre-CDR, 2015) and the Conceptual Design Report (CDR, 2018), comprehensively detailing the machine's layout and performance, physical design and analysis, technical systems design, R&D and prototyping efforts, and associated civil engineering aspects. Additionally, it includes a cost estimate and a preliminary construction timeline, establishing a framework for forthcoming engineering design phase and site selection procedures. Construction is anticipated to begin around 2027-2028, pending government approval, with an estimated duration of 8 years. The commencement of experiments could potentially initiate in the mid-2030s

    Additional file 1 of Risks of digestive diseases in long COVID: evidence from a population-based cohort study

    No full text
    Additional file 1: Figure S1. Directed Acyclic Graphs (DAG) for covariate selection. Figure S2. Flow chart of eligible participants’ selection. Figure S3. Distribution of follow-up time in the contemporary cohort (A) and the historical cohort (B). Figure S4. Hazard ratio of digestive outcomes in COVID-19 group and the contemporary comparison by severity of COVID-19. Table S1. Respiratory support treatments definition. Table S2. Outcome ascertainment. Table S3. The numbers (percentages) of participants with missing covariates. Table S4. Baseline characteristics of COVID-19 group and contemporary comparisons before weighting. Table S5. Hazard ratio of digestive outcomes in COVID-19 group and the contemporary comparison at different follow-up times. Table S6. Baseline characteristics of COVID-19, contemporary comparisons by severity of COVID-19 before weighting. Table S7. Baseline characteristics of COVID-19, contemporary comparisons by severity of COVID-19 after weighting. Table S8. Baseline characteristics of COVID-19 group and contemporary comparisons by status of SARS-CoV reinfection before weighting. Table S9. Baseline characteristics of COVID-19 group and contemporary comparisons by severity of SARS-CoV reinfection after weighting. Table S10. Hazard ratio of digestive outcomes in the reinfected group, single SARS-CoV-2 infection group, and non-infected comparisons. Table S11. Hazard ratio of digestive outcomes in reinfected group and single SARS-CoV-2 infection group in head-to-head comparison. Table S12. Baseline characteristics of COVID-19 group and contemporary comparisons in the sensitive analysis restricting to the period before vaccination was available before weighting. Table S13. Baseline characteristics of COVID-19 group and contemporary comparisons in the sensitive analysis restricting to the period before vaccination was available after weighting. Table S14. Hazard ratio of digestive outcomes in COVID-19 group and contemporary and historical comparisons in subgroups in the sensitive analysis restricting to the period before vaccination was available. Table S15. Hazard ratio of digestive outcomes in COVID-19 group compared to the contemporary and historical comparisons by pooling estimates across all five imputed datasets. Table S16. Hazard ratio of digestive outcomes compared with contemporary and historical comparisons in subgroups. Table S17. Hazard ratio of digestive outcomes in COVID-19 group, the contemporary and historical comparison by sex. Table S18. Baseline characteristics of COVID-19 group and historical comparisons before weighting. Table S19. Baseline characteristics of COVID-19 group and historical comparisons after weighting. Table S20. Baseline characteristics of COVID-19 group and historical comparisons by severity of COVID-19 before weighting. Table S21. Baseline characteristics of COVID-19 group and historical comparisons by severity of COVID-19 after weighting. Table S22. Baseline characteristics of COVID-19 group and historical comparisons in the sensitive analysis restricting to the period before vaccination was available before weighting. Table S23. Baseline characteristics of COVID-19 group and historical comparisons in the sensitive analysis restricting to the period before vaccination was available after weighting. Table S24. Hazard ratio of digestive outcomes in COVID-19 group and the historical comparison by severity of COVID-19

    CEPC Technical Design Report -- Accelerator

    No full text
    International audienceThe Circular Electron Positron Collider (CEPC) is a large scientific project initiated and hosted by China, fostered through extensive collaboration with international partners. The complex comprises four accelerators: a 30 GeV Linac, a 1.1 GeV Damping Ring, a Booster capable of achieving energies up to 180 GeV, and a Collider operating at varying energy modes (Z, W, H, and ttbar). The Linac and Damping Ring are situated on the surface, while the Booster and Collider are housed in a 100 km circumference underground tunnel, strategically accommodating future expansion with provisions for a Super Proton Proton Collider (SPPC). The CEPC primarily serves as a Higgs factory. In its baseline design with synchrotron radiation (SR) power of 30 MW per beam, it can achieve a luminosity of 5e34 /cm^2/s^1, resulting in an integrated luminosity of 13 /ab for two interaction points over a decade, producing 2.6 million Higgs bosons. Increasing the SR power to 50 MW per beam expands the CEPC's capability to generate 4.3 million Higgs bosons, facilitating precise measurements of Higgs coupling at sub-percent levels, exceeding the precision expected from the HL-LHC by an order of magnitude. This Technical Design Report (TDR) follows the Preliminary Conceptual Design Report (Pre-CDR, 2015) and the Conceptual Design Report (CDR, 2018), comprehensively detailing the machine's layout and performance, physical design and analysis, technical systems design, R&D and prototyping efforts, and associated civil engineering aspects. Additionally, it includes a cost estimate and a preliminary construction timeline, establishing a framework for forthcoming engineering design phase and site selection procedures. Construction is anticipated to begin around 2027-2028, pending government approval, with an estimated duration of 8 years. The commencement of experiments could potentially initiate in the mid-2030s

    CEPC Technical Design Report -- Accelerator

    No full text
    International audienceThe Circular Electron Positron Collider (CEPC) is a large scientific project initiated and hosted by China, fostered through extensive collaboration with international partners. The complex comprises four accelerators: a 30 GeV Linac, a 1.1 GeV Damping Ring, a Booster capable of achieving energies up to 180 GeV, and a Collider operating at varying energy modes (Z, W, H, and ttbar). The Linac and Damping Ring are situated on the surface, while the Booster and Collider are housed in a 100 km circumference underground tunnel, strategically accommodating future expansion with provisions for a Super Proton Proton Collider (SPPC). The CEPC primarily serves as a Higgs factory. In its baseline design with synchrotron radiation (SR) power of 30 MW per beam, it can achieve a luminosity of 5e34 /cm^2/s^1, resulting in an integrated luminosity of 13 /ab for two interaction points over a decade, producing 2.6 million Higgs bosons. Increasing the SR power to 50 MW per beam expands the CEPC's capability to generate 4.3 million Higgs bosons, facilitating precise measurements of Higgs coupling at sub-percent levels, exceeding the precision expected from the HL-LHC by an order of magnitude. This Technical Design Report (TDR) follows the Preliminary Conceptual Design Report (Pre-CDR, 2015) and the Conceptual Design Report (CDR, 2018), comprehensively detailing the machine's layout and performance, physical design and analysis, technical systems design, R&D and prototyping efforts, and associated civil engineering aspects. Additionally, it includes a cost estimate and a preliminary construction timeline, establishing a framework for forthcoming engineering design phase and site selection procedures. Construction is anticipated to begin around 2027-2028, pending government approval, with an estimated duration of 8 years. The commencement of experiments could potentially initiate in the mid-2030s

    CEPC Technical Design Report -- Accelerator