1,111 research outputs found

    Limited Testing at the Bob Turbeville Site (41WD382), Wood County, Texas

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    The Bob Turbeville site (41WD382) is an Early to Middle Caddoan period occupation on the upper Sabine River, likely a small farmstead or hamlet containing a trash midden and possible house areas. Previous work at the site had identified a human burial with associated grave goods. Radiocarbon analysis suggests that the occupation of the site dates to around A.D. 1165 to 1290. Work at the Turbeville site was conducted in October 1995 by Paul Price Associates, Inc. under the auspices of the Antiquities Code of Texas in association with a proposed expansion of the existing wastewater treatment facilities at Mineola, Texas. The site is located just south of Mineola, along the slope and valley margin of a dissected landform that projects out above extensive Pleistocene terrace deposits of the Sabine River. Two unnamed tributaries bisect the terrace deposits to the east and west of the site

    An Intensive Cultural Resources Survey of the Proposed Uvalde Memorial Hospital Demolition and Reconstruction Project Uvalde County, Texas

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    The Uvalde County Hospital Authority has applied for a U.S. Department of Agriculture (USDA) Rural Development funding to demolish its existing Uvalde Memorial Hospital complex and construct a new hospital and associated facilities. The new complex will be constructed on an undeveloped 11.5-acre tract immediately south of the existing complex. Those facilities proposed for demolition consist of the original Uvalde Memorial Hospital building, the current main hospital building, a warehouse building, and the central plant building. The original hospital building dates to 1949 while all other buildings to be demolished date to 1971 or later. The Kate Marmion Regional Cancer Medical Center which was built in 2011 will not be demolished according to the current plan. New facilities to be constructed consist of a new hospital building, new warehouse and central plant buildings, and associated parking lots. At the request of the State Historic Preservation Officer (SHPO) at the Texas Historical Commission (THC), Applied Archeological Sciences, Inc. (AASI) conducted an archeological survey of the 11.5 acre undeveloped portion of the Area of Potential Effect (APE) in February 2017. Additionally, at the SHPO\u27s request, AASI photographed the exterior 1949- era hospital building. The purpose of the investigations was to identify and determine the potential impacts to any historic properties that may be eligible for listing on the National Register of Historic Places (NRHP) and/or eligible for formal designation as State Archeological Landmarks (SAL) in accordance with the National Historic Preservation Act as amended, and the Antiquities Code of Texas, respectively. The entire 11.5 acre was surveyed with one new archeological site, 41UV505, being recorded and assessed. This site is a prehistoric open campsite that is situated in the southwestern corner of the survey area. The site also extends southward outside the project area. Cultural materials found within the 40 to 60 cm thick deposits are sparse and are restricted to chert chipping debris, an edge-modified chert flake, a chert core, and small burned rock fragments. No intact prehistoric features or diagnostic artifacts were found. The portion of site 41UV505 within the project area is recommended as not eligible for listing on the NRHP and not eligible for formal designation as a SAL. No additional archeological investigations at 41UV505 are recommended. Photographs of the 1949-era hospital building have been submitted with this draft report for review by the SHPO. Demolition of this building should not move forward until the SHPO has completed review of this building. No artifacts were collected during the project. All records associated with the archeological investigation will be curated at the Center for Archeological Research at the University of Texas at San Antonio

    Mapping the UK Webspace: Fifteen Years of British Universities on the Web

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    This paper maps the national UK web presence on the basis of an analysis of the .uk domain from 1996 to 2010. It reviews previous attempts to use web archives to understand national web domains and describes the dataset. Next, it presents an analysis of the .uk domain, including the overall number of links in the archive and changes in the link density of different second-level domains over time. We then explore changes over time within a particular second-level domain, the academic subdomain .ac.uk, and compare linking practices with variables, including institutional affiliation, league table ranking, and geographic location. We do not detect institutional affiliation affecting linking practices and find only partial evidence of league table ranking affecting network centrality, but find a clear inverse relationship between the density of links and the geographical distance between universities. This echoes prior findings regarding offline academic activity, which allows us to argue that real-world factors like geography continue to shape academic relationships even in the Internet age. We conclude with directions for future uses of web archive resources in this emerging area of research.Comment: To appear in the proceeding of WebSci 201

    Clinical Outcomes After Four-Level Anterior Cervical Discectomy and Fusion.

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    Study Design: Retrospective cohort study. Objectives: Anterior cervical discectomy and fusion (ACDF) demonstrates reliable improvement in neurologic symptoms associated with anterior compression of the cervical spine. There is a paucity of data on outcomes following 4-level ACDFs. The purpose of this study was to evaluate clinical outcomes for patients undergoing 4-level ACDF. Methods: All 4-level ACDFs with at least 1-year clinical follow-up were identified. Clinical outcomes, including fusion rates, neurologic outcomes, and reoperation rates were determined. Results: Retrospective review of our institutional database revealed 25 patients who underwent 4-level ACDF with at least 1-year clinical follow-up. Average age was 57.5 years (range 38.2-75.0 years); 14 (56%) were male, and average body mass index was 30.2 kg/m Conclusions: Review of our institution\u27s experience demonstrated a low rate of revision cervical surgery for any reason of 8% at mean 19 months follow-up, and neurological examinations consistently improved, despite a high rate of radiographic nonunion (31%)

    Mature sperm small-RNA profile in the sparrow: implications for transgenerational effects of age on fitness.

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    Mammalian sperm RNA has recently received a lot of interest due to its involvement in epigenetic germline inheritance. Studies of epigenetic germline inheritance have shown that environmental exposures can induce effects in the offspring without altering the DNA sequence of germ cells. Most mechanistic studies were conducted in laboratory rodents and C.elegans while observational studies confirm the phenotypic phenomenon in wild populations of humans and other species including birds. Prominently, paternal age in house sparrows affects offspring fitness, yet the mechanism is unknown. This study provides a first reference of house sparrow sperm small RNA as an attempt to uncover their role in the transmission of the effects of paternal age on the offspring. In this small-scale pilot, we found no statistically significant differences between miRNA and tRNA fragments in aged and prime sparrow sperm. These results indicate a role of other epigenetic information carriers, such as distinct RNA classes, RNA modifications, DNA methylation and retained histones, and a clear necessity of future studies in wild populations.This work was supported by Cancer Research UK (C13474/A18583, C6946/A14492) and the Wellcome Trust (104640/Z/14/Z, 092096/Z/10/Z) through E.A.M. W.M. was funded by The Nakajima Foundation and St John’s College Benefactors’ Scholarship. K.G. received funding from the Swiss National Science Foundation advanced mobility fellowship. J.S. was supported by Imperial College London

    Observational evidence for the convective transport of dust over the central United States

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    Bulk aerosol composition and aerosol size distributions measured aboard the DC-8 aircraft during the Deep Convective Clouds and Chemistry Experiment mission in May/June 2012 were used to investigate the transport of mineral dust through nine storms encountered over Colorado and Oklahoma. Measurements made at low altitudes (\u3c5‚ÄČkm mean sea level (MSL)) in the storm inflow region were compared to those made in cirrus anvils (altitude‚ÄČ\u3e‚ÄČ9‚ÄČkm MSL). Storm mean outflow Ca2+ mass concentrations and total coarse (1‚ÄȬĶm‚ÄČ\u3c‚ÄČdiameter‚ÄČ\u3c‚ÄČ5‚ÄȬĶm) aerosol volume (Vc) were comparable to mean inflow values as demonstrated by average outflow/inflow ratios greater than 0.5. A positive relationship between Ca2+, Vc, ice water content, and large (diameter‚ÄČ\u3e‚ÄČ50‚ÄȬĶm) ice particle number concentrations was not evident; thus, the influence of ice shatter on these measurements was assumed small. Mean inflow aerosol number concentrations calculated over a diameter range (0.5‚ÄȬĶm‚ÄČ\u3c‚ÄČdiameter‚ÄČ\u3c‚ÄČ5.0‚ÄȬĶm) relevant for proxy ice nuclei (NPIN) were ~15‚Äď300 times higher than ice particle concentrations for all storms. Ratios of predicted interstitial NPIN (calculated as the difference between inflow NPIN and ice particle concentrations) and inflow NPIN were consistent with those calculated for Ca2+ and Vc and indicated that on average less than 10% of the ingested NPIN were activated as ice nuclei during anvil formation. Deep convection may therefore represent an efficient transport mechanism for dust to the upper troposphere where these particles can function as ice nuclei cirrus forming in situ

    The effect of hypothermia on influx of leukocytes in the digital lamellae of horses with oligofructose-induced laminitis

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    Sepsis-related laminitis (SRL) is a common complication in the septic/endotoxemic critically-ill equine patient, in which lamellar injury and failure commonly lead to crippling distal displacement of the distal phalanx. Similar to organ injury in human sepsis, lamellar injury in SRL has been associated with inflammatory events, including the influx of leukocytes into the lamellar tissue and markedly increased expression of a wide array of inflammatory mediators at the onset of Obel grade 1 (OG1) laminitis. The only treatment reported both clinically and experimentally to protect the lamellae in SRL, local hypothermia (‚Äúcryotherapy‚ÄĚ), has been demonstrated to effectively inhibit lamellar expression of multiple inflammatory mediators when initiated at the time of administration of a carbohydrate overload in experimental models of SRL. However, the effect of hypothermia on leukocyte influx into affected tissue has not been assessed. We hypothesized that cryotherapy inhibits leukocyte emigration into the digital lamellae in SRL. Immunohistochemical staining using leukocyte markers MAC387 (marker of neutrophils, activated monocytes) and CD163 (monocyte/macrophage-specific marker) was performed on archived lamellar tissue samples from an experimental model of SRL in which one forelimb was maintained at ambient temperature (AMB) and one forelimb was immersed in ice water (ICE) immediately following enteral oligofructose administration (10\ua0g/kg, n\ua0=\ua014 horses). Lamellae were harvested at 24\ua0h post-oligofructose administration (DEV, n\ua0=\ua07) or at the onset of OG1 laminitis (OG1, n\ua0=\ua07). Both MAC387-positive and CD163-positive cells were counted by a single blinded investigator on images [n\ua0=\ua010 (40√ó fields/digit for MAC387 and 20\ua0x fields/digit for CD163)] obtained using Aperio microscopy imaging analysis software. Data were assessed for normality and analyzed with a paired t-test and one-way ANOVA with significance set at p\ua
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