1,847 research outputs found

    Evolution: A evolução no ensino de surdos

    Get PDF
    Metadados do Trabalho de Conclusão de Curso: Evolution: A evolução no ensino de surdos, pela discente: Raquel Rodrigues Dias, sob Orientação de Arlindo Costa do curso de Especialização em Atendimento Educacional Especializado na perspectiva da Educação Inclusiva (2015-2016) da Universidade Federal da Integração Latino-Americana (UNILA), no Repositório Institucional da UNILA (RI-UNILA)Evolution: A evolução no ensino de surdo

    Novos eléctrodos à base de materiais porosos redox-ativos para baterias mais eficientes

    Get PDF
    Today the energy sector is still the main contributor towards global warming, raising the urgency for a faster transition from fossil fuels to cleaner energy sources. Due to the renewable‚Äôs intermittent availability problem, there is an increased need for better, safer, and more sustainable energy storage solutions. This work focuses on the use of covalent organic frameworks, a type of organic polymers, as electrode materials for lithium-ion batteries. First, the focus was on the synthesis and characterization of redox-active COFs, as well as the design of new COFs with expected increased conductivity. Afterward, the synthesized materials were used as electrodes in coin-cell type lithium batteries. For that purpose, the electrode preparation process was optimized, and the batteries were manufactured and tested. Thus, uncovering relations between covalent organic frameworks and their application as electrode materials for energy storage devices.Atualmente, o setor energ√©tico continua a ser o principal contribuidor para o aquecimento global, tornando cada vez mais urgente a transi√ß√£o energ√©tica de combust√≠veis f√≥sseis para fontes de energia mais limpas. Devido ao problema da disponibilidade intermitente de energia de origem renov√°vel, h√° uma necessidade cada vez maior para solu√ß√Ķes de armazenamento energ√©tico melhores, mais seguras e mais sustent√°veis. Esta disserta√ß√£o foca-se no uso de Estruturas Org√Ęnicas Covalentes (COFs), um tipo de pol√≠mero org√Ęnico, para o uso como material ativo em el√©trodos de baterias i√£o l√≠tio. Numa fase inicial, o trabalho focou-se na s√≠ntese e caracteriza√ß√£o de novos materiais porosos redox-ativos, assim como, no design de novos COFs com condutividade el√©trica mais elevada. Posteriormente, os mat√©rias sintetizados foram usados como el√©trodos em baterias. Para esse fim, o processo de prepara√ß√£o do el√©trodo foi otimizado e as baterias fabricadas e testadas. Assim, foram analisadas as rela√ß√Ķes entre as estruturas org√Ęnicas covalentes e a sua aplica√ß√£o em materiais de armazenamento energ√©tico.Mestrado em Engenharia Qu√≠mic

    The predictors of financial well-being and its impact on overall well-being: the case of Portugal

    Get PDF
    Although overall well-being is a well study phenomenon, financial well-being only recently has taken interest in the research field. Accordingly, the aim of this study is to understand the relation between financial well-being, its predictors (financial status, financial behaviour, financial knowledge and financial attitudes) and overall well-being. Additionally, hypotheses were tested with age, gender, household income and area of residence. It was used the quantitative method to gather the data, and to analyse it, the SPPS through linear regression analysis, mediation analysis, independent t-test and an anova test. Regarding the results, the financial status is the only positive and significant impactor on financial well-being and the latter has a significant positive relation with overall well-being. It was also found that financial well-being was a mediator between financial status and overall well-being. Overall, the other predictors did not show a significant effect. Moreover, higher household incomes contribute to increase the financial well-being. Plus, I found that there were differences in financial wellbeing between groups. For example, the older you get does not necessarily implies a higher financial satisfaction. Overall, men appear to have a higher financial well-being than women. In sum, these results show a multidisciplinary concept of overall well-being and that individuals prioritise financial security over the other components. In terms of practical implications, this research is relevant because it highlights the evidence of financial status‚Äô importance in predicting financial well-being, as well as the role of household income for individual financial satisfaction.Embora o bem-estar geral seja um fen√≥meno bem estudado, o bem-estar financeiro s√≥ recentemente se tornou interessante no campo da investiga√ß√£o. Consequentemente, o objetivo do estudo √© entender a rela√ß√£o entre o bem-estar financeiro, seus antecedentes (status financeiro, comportamento financeiro, conhecimento financeiro e atitudes financeiras) e o bem-estar geral. Adicionalmente, foram testadas hip√≥teses com a idade, g√©nero, rendimento familiar e √°rea de resid√™ncia. Foi utilizado o m√©todo quantitativo para reunir os dados, e para a sua an√°lise, o SPPS atrav√©s da an√°lise de regress√£o linear, an√°lise de media√ß√£o, independente t-teste e o anova teste. Em rela√ß√£o aos resultados, o status financeiro √© o √ļnico e significante fator positivo no bem-estar financeiro e este √ļltimo tem uma rela√ß√£o positiva significativa com o bem-estar geral. Constatou-se tamb√©m que o bem-estar financeiro √© o mediador entre o status financeiro e bem-estar geral. No geral, os outros antecedentes n√£o mostraram um efeito significativo. Al√©m disso, elevado rendimento familiar contribui para aumentar o bem-estar financeiro. Adicionalmente, encontrei diferen√ßas no bem-estar financeiro entre grupos. Por exemplo, ao envelhecer n√£o implica necessariamente numa maior satisfa√ß√£o financeira. No geral, os homens t√™m um maior bem-estar financeiro do que as mulheres. Em suma, estes resultados mostram um conceito multidisciplinar de bem-estar geral e que os indiv√≠duos d√£o primazia √† seguran√ßa financeira sobre os outros componentes. Em termos de implica√ß√Ķes pr√°ticas, esta pesquisa √© relevante porque evidencia a import√Ęncia do status financeiro na previs√£o do bem-estar financeiro, bem como o papel do rendimento familiar para satisfa√ß√£o financeira individual

    Rela√ß√£o existente entre as exporta√ß√Ķes e as restri√ß√Ķes financeiras das empresas industriais do setor t√™xtil

    Get PDF
    Disserta√ß√£o de Mestrado em Finan√ßas EmpresariaisA presente disserta√ß√£o visa verificar qual a rela√ß√£o existente entre Exporta√ß√Ķes e Restri√ß√Ķes Financeiras das Empresas Industriais do Setor T√™xtil portugu√™s. A maioria da literatura te√≥rica e emp√≠rica de finan√ßas internacionais, tende a afirmar que as restri√ß√Ķes financeiras impedem o crescimento e a internacionaliza√ß√£o das empresas; contudo, s√£o poucos os autores que conseguem provar empiricamente e explicar o porqu√™ das exporta√ß√Ķes poderem aumentar o acesso das empresas a fundos financeiros externos e, por conseguinte, poderem vir a diminuir as restri√ß√Ķes financeiras, melhorando a sa√ļde financeira dessas empresas. No presente trabalho, para estudo dos problemas mencionados anteriormente, a an√°lise emp√≠rica ser√° feita atrav√©s do uso conjunto de duas bases de dados microecon√≥micas (no per√≠odo 1996-2003) fornecidas pelo Instituto Nacional de Estat√≠stica (INE) e referentes a dados econ√≥mico-financeiros e a exporta√ß√Ķes. A metodologia escolhida para a medi√ß√£o das restri√ß√Ķes financeiras passa pela cria√ß√£o de um score financeiro, na sequ√™ncia da proposta de Musso e Schiavo, (2008). Com esta disserta√ß√£o, pretendemos averiguar qual o score de restri√ß√Ķes financeiras sentidas pelas empresas da amostra, avaliar at√© que ponto as restri√ß√Ķes financeiras s√£o ou n√£o um entrave ao in√≠cio da atividade e verificar se as exporta√ß√Ķes efetivamente melhoram a sa√ļde financeira das empresas. Dos resultados obtidos, atrav√©s de an√°lise de regress√£o, sugere-se a ideia de que existe de facto a autosele√ß√£o das empresas menos restringidas financeiramente para a futura atividade exportadora e ainda que as novas empresas exportadoras mostram melhorias na sua situa√ß√£o financeira.The purpose of the following dissertation is to verify the existing relationship between Exports and Financial Restrictions of the Industrial Companies of the Portuguese Textile Sector. The majority of the existing theoretical and empirical literature regarding international finances tends to claim that financial restrictions prevent the growth and the internationalization of companies; however, there are few authors that can prove empirically and explain why do exports have the potential to increase the companies‚Äô access to foreign financial funds and, as a consequence, decrease their financial restrictions, increasing the financial health of these companies. In this dissertation, to study the problems previously mentioned, the empirical analysis will be made through the conjoined use of two micro- economical databases (from the 1996-2003 period), provided by the National Statistics Institute (INE) and pertaining to financial-economical data and exports. The chosen methodology for the measurement of the financial restrictions starts with the creation of a financial score, in lieu of the proposal from Musso and Schiavo, (2008). With this dissertation, we seek to discover what is the score of financial restrictions felt by the companies in our sample, to evaluate to what extent are financial restrictions a hindrance to the beginning of activity, and to verify if exports effectively improve the companies‚Äô financial health. From our collected results, through regression analysis, we suggest the idea that there is in fact an auto-selection from the less financially restricted companies towards future exporting activity, and also that the new exporting companies show improvement in their financial situation

    Application of empirical mode decomposition (EMD) to chronological series of active fires from MODIS satellite

    Get PDF
    Mestrado em Engenharia Florestal e dos Recursos Naturais - Instituto Superior de AgronomiaFire is a global phenomenon, acting as an important disturbance process. Africa is one of the continents that has higher fire density, particularly in savanna regions, making it the subject of innumerous studies about fire regime and behavior. Here, a new method of time series analysis called Empirical Mode Decomposition (EMD) was applied to monthly fire counts time series from MODIS Terra/Aqua sensors. The goals were to analyze the differences between the time series from the two instruments (MODIS Terra and Aqua), the differences in the behavior of the active fire time series from the north and south parts of Africa and they‚Äüre relationships with climatic modes (ENSO and IOD). For most of the time series, the application of the EMD resulted in four IMF‚Äüs and a residue. Although there is always an IMF related with seasonality, the physical meaning of the other isn‚Äüt clear. This may be due to various reasons, some related with intrinsic problems of the method, other with the applicability of the method to this type of series

    Representa√ß√Ķes de g√™nero na publicidade televisiva infantil: as perce√ß√Ķes e a literacia para a publicidade das crian√ßas

    Get PDF
    Children are becoming consumers at increasingly younger age and are more influential in consumption decisions within the family. Television still is one of the main ways they are exposed to advertising. Our study focuses on gender stereotypes on TV advertisements for children and combines a content analysis of advertisements and focus groups with children between 7 and 12 years old. Our findings show that, during a period of 3 months, about 75% of TV advertisements for children contain gender stereotypes. In addition, children are able to recognize such stereotypes, and in general do not identify or agree with the way each gender is portrayed. Finally, children display good levels of advertising literacy, as they are able to recognize the intentions of the brands in the commercials.As crian√ßas tornam-se consumidores cada vez mais cedo, e s√£o cada vez mais influentes no consumo da fam√≠lia. A televis√£o ainda √© uma das principais formas atrav√©s das quais s√£o expostas √† publicidade. O nosso estudo, realizado em Portugal, foca-se em estere√≥tipos de g√™nero na publicidade televisiva infantil e combina uma an√°lise de conte√ļdo a an√ļncios com grupos de discuss√£o com crian√ßas entre os 8 e os 12 anos. Os nossos resultados mostram que, em 3 meses, 75% dos an√ļncios televisivos para crian√ßas continham estere√≥tipos de g√™nero. As crian√ßas s√£o capazes de reconhecer esses estere√≥tipos e, em geral, n√£o se identificam ou n√£o concordam com essas representa√ß√Ķes dos g√™neros. Finalmente, as crian√ßas revelaram bons n√≠veis de literacia para a publicidade, sendo capazes de reconhecer a inten√ß√£o persuasiva das marcas.info:eu-repo/semantics/publishedVersio

    Is Canada back? Human security and national unity during the Governments of Jean Chrétien and Justin Trudeau

    Get PDF
    Disserta√ß√£o de mestrado em Ci√™ncia Pol√≠ticaA search for national purpose has always played a central role throughout the several governments of Canada. Particularly after the end of World War II, the Golden Years of Canadian Foreign Policy were inaugurated, a broad slogan which Canadians assume as part of their existence as a political community, thus establishing a parallel between National Unity and Foreign Policy. Such approach brands Canada as a mediatory middle power, remarked by a permanent engagement and cooperative behavior, endorsing universal values through the promotion of a more institutionalized and just international world order: a vision with permanent presence in its processes of agenda setting and execution. Framed within the broad agenda of internationalism, different liberal governments have branded their political program in order to rescue the Golden Age and achieve their political interests may these be internal, external, or both. This thesis starts by analyzing how the Human Security Agenda emerged through the Government of Jean Chr√©tien during the 1990‚Äôs as a response to an internal crisis of national unity in the eve of the Quebec Referendum, calling for a sense of national unity among Canadians by increasing their sense of national pride and belonging, also being remarked as the last internationalist period in Canadian politics. In the eve of the 2015 federal election, Justin Trudeau has brought to discourse the so called Canadian liberal values after a decade of Conservative rule, offering a positive and even nostalgic vision of Canada by enhancing the need to return liberal internationalism to Canadian politics. Once in power, Trudeau announced that ‚ÄúCanada is back‚ÄĚ, opening the door for an innovative, idealistic and very personal styled Foreign Policy agenda that Canadians identified with and even a likely possibility of rebuilding a new Human Security Agenda. However, much of Trudeau‚Äôs rhetoric has lost credibility as its actions and experiences as prime minister did not keep up with the promised idealistic brand for a too turbulent world.A busca por um sentido de unidade nacional desempenhou sempre um papel central nos v√°rios governos do Canad√°. Com o final da Segunda Guerra Mundial foram inaugurados os Anos Dourados da Pol√≠tica Externa Canadiana, um amplo slogan que os canadianos assumem como parte de sua exist√™ncia enquanto comunidade pol√≠tica, estabelecendo um paralelo entre Unidade Nacional e Politica Externa. Tal abordagem demarca o Canad√° como uma pot√™ncia m√©dia moderadora, conhecida por um envolvimento permanente e um comportamento cooperativo na defesa de valores universais na promo√ß√£o de uma ordem mundial internacional mais institucionalizada e justa: uma vis√£o com presen√ßa permanente nos seus processos de defini√ß√£o e execu√ß√£o da agenda politica. Enquadrados na ampla agenda do internacionalismo, diferentes governos liberais rotularam o seu programa pol√≠tico para resgatar a Idade de Ouro e alcan√ßar os seus interesses pol√≠ticos, sejam estes internos, externos ou ambos. Esta tese come√ßa por analisar de que forma a Agenda de Seguran√ßa Humana emerge atrav√©s do governo de Jean Chr√©tien durante os anos 90 enquanto resposta a uma crise interna de unidade nacional na v√©spera do referendo do Qu√©bec que exigiu um novo sentido de unidade nacional entre os canadianos, aumentando o seu sentimento de orgulho e perten√ßa, sendo tamb√©m considerado como o √ļltimo per√≠odo internacionalista na pol√≠tica canadiana. Na v√©spera da elei√ß√£o federal de 2015, Justin Trudeau discursou acerca dos chamados valores liberais canadianos ap√≥s uma d√©cada de governo conservador, oferecendo uma vis√£o positiva e at√© nost√°lgica do Canad√°, aumentando a necessidade de retornar o internacionalismo liberal √† pol√≠tica canadiana. Uma vez no poder, Trudeau anunciou que ‚Äúo Canad√° est√° de volta‚ÄĚ, abrindo as portas para uma agenda de pol√≠tica externa, inovadora, idealista e muito pessoal, com a qual os canadianos se identificaram e at√© mesmo uma possibilidade de reconstruir uma nova agenda de seguran√ßa humana. No entanto, grande parte da ret√≥rica de Trudeau perdeu credibilidade uma vez que as suas a√ß√Ķes e experi√™ncias como Primeiro-Ministro n√£o acompanharam a prometida marca idealista para um mundo demasiado turbulento

    Trypanosoma brucei effect on leukocyte differentiation and activation

    Get PDF
    Tripanossom√≠ase Africana ou doen√ßa do sono √© uma doen√ßa zoon√≥tica causada por Trypanosoma brucei, um protozo√°rio parasita transmitido pela mosca tsetse ou Glossina. A introdu√ß√£o do parasita no hospedeiro vertebrado provoca uma sucess√£o de eventos que envolvem a imunidade inata e adaptativa. Os macr√≥fagos (Mő¶) apresentam um papel fundamental na defesa inata por serem c√©lulas apresentadoras profissionais de antig√©nio (APC) e c√©lulas fagoc√≠ticas, importantes na elimina√ß√£o dos tripanossomas. A imunidade adaptativa √© assegurada pelos linf√≥citos, nomeadamente pelos linf√≥citos T. Contudo, o papel desempenhado por estas c√©lulas imunit√°rias ainda n√£o se encontra completamente clarificado. Assim, este estudo teve como objetivo analisar a atividade dos Mő¶ na infe√ß√£o por T. brucei, avaliando os n√≠veis de ureia e √≥xido n√≠trico (NO) e a express√£o membranar das mol√©culas de classe I (MHCI) e classe II (MHCII) do complexo principal de histocompatibilidade. A diferencia√ß√£o das popula√ß√Ķes linfocit√°rias, T helper (Th), T citot√≥xicas (Tc) e T reguladoras foi tamb√©m avaliada. Mő¶ de murganho foram expostos a tripomastigotas de T. brucei e estimulados com antig√©nio total e exossomas de T. brucei. A caracteriza√ß√£o da ativa√ß√£o macrof√°gica atrav√©s de ensaios colorim√©tricos demonstrou que ambos os fen√≥tipos M1 e M2 foram expressos e foi evidenciada correla√ß√£o positiva entre a produ√ß√£o de ureia e de NO. Adicionalmente, os resultados da citometria de fluxo indicaram que o parasita prejudica a diferencia√ß√£o das subpopula√ß√Ķes de Mő¶MHCI+ e Mő¶MHCII+ mas induz o aumento de mol√©culas MHCI. Contrariamente, os exossomas demonstraram estimular as fun√ß√Ķes APC atrav√©s das mol√©culas MHCI e MHCII. Os r√°cios MHCI/MHCII indicaram que o contacto com o parasita favorece a apresenta√ß√£o antig√©nica √†s c√©lulas TCD4+, enquanto que os exossomas direcionam a apresenta√ß√£o antig√©nica para as subpopula√ß√Ķes de linf√≥citos TCD4+ e TCD8+. A carateriza√ß√£o das popula√ß√Ķes linfocit√°rias atrav√©s da citometria de fluxo demonstrou que T. brucei causa a diminui√ß√£o das popula√ß√Ķes de linf√≥citos Th e Tc. Contrariamente, a estimula√ß√£o com o antig√©nio total ou com os exossomas induziram a expans√£o de ambas as subpopula√ß√Ķes linfocit√°rias. T. brucei parece promover a expans√£o das subpopula√ß√Ķes linfocit√°rias CD8-CD25+FoxP3- e CD8+CD25+FoxP3-. A expans√£o da subpopula√ß√£o celular CD25-FoxP3+ foi observada na fra√ß√£o celular CD8- ap√≥s estimula√ß√£o do antig√©nio e na fra√ß√£o celular CD8+ estimulada por exossomas. Al√©m disso, os exossomas tamb√©m promoveram a expans√£o da subpopula√ß√£o de linf√≥citos T CD8+CD25+FoxP3+. Curiosamente, apesar da contra√ß√£o celular T. brucei induziu o aumento das mol√©culas FoxP3. Em conjunto, os resultados obtidos indicam que o parasita e os exossomas parecem exercer efeitos opostos nas c√©lulas analisadas. Os parasitas parecem minimizar a apresenta√ß√£o antig√©nica e evitam induzir a expans√£o das subpopula√ß√Ķes de linf√≥citos T, facilitando a sua perman√™ncia no hospedeiro. Por outro lado, os exossomas segregados por T. brucei parecem estimular a apresenta√ß√£o antig√©nica e mediar a expans√£o dos linf√≥citos Th, possivelmente deslocando o foco da atividade do sistema imunit√°rio dos parasitas para os exossomas. Estes resultados permitiram clarificar alguns dos princ√≠pios subjacentes √† resposta imunit√°ria inata e adaptativa na fase inicial da infe√ß√£o. A compreens√£o destes mecanismos pode vir a contribuir para o desenvolvimento de novas estrat√©gias de controlo e elimina√ß√£o da Tripanossom√≠ase Africana.African trypanosomiasis or sleeping sickness is a zoonotic disease caused by Trypanosoma brucei, a protozoan parasite transmitted by tsetse fly or Glossina. Parasite introduction into mammal hosts, triggers a succession of events, involving both innate and adaptive immunity. Macrophages (Mő¶) have a key role in innate defense, since they are antigen-presenting cells (APC) and have a phagocytosis function essential for trypanosomes clearance. Adaptive immune defense is carried out by lymphocytes, in particular by T lymphocytes. However, the exact role of these immune cells remains not completely understood. Thus, this study aimed to assess the role of Mő¶ in T. brucei infection by measuring the urea and nitric oxide (NO) levels, and by evaluating membrane expression of class I (MHCI) and class II (MHCII) molecules of major histocompatibility complex. The differentiation of T helper (Th), T cytotoxic (Tc) and T regulatory cell subsets was assessed. Mouse Mő¶ were exposed to T. brucei trypomastigotes and stimulated by T. brucei extract and T. brucei exosomes. Characterization of Mő¶ activation with colorimetric assays have indicated that both M1 and M2 phenotypes were expressed, evidencing a positive correlation between urea and NO levels produced. Additionally, results of flow cytometry indicated that T. brucei impairs the expansion of both MHCI+ and MHCII+ Mő¶ subsets, but enhanced MHCI molecules. On the contrary, T. brucei exosomes stimulated APC functions through MHCI and MHCII molecules. MHCI/MHCII rates indicated that T. brucei shift the antigen presentation to CD4+ T cells, while exosomes directed the antigen presentation to both CD4+ and CD8+ T cells. Characterization of lymphocyte subsets by flow cytometry demonstrated that T. brucei impairs both Th and Tc lymphocytes. On the contrary, cell stimulation by extract and exosomes promote the expansion of both T cell subpopulations. T. brucei seem to promote the expansion of CD8-CD25+FoxP3- and CD8+CD25+FoxP3- T cell subsets. The expansion of CD25-FoxP3+ T cell subset was observed in CD8- cell fraction antigen stimulated and in the CD8+ cell fraction exosome stimulated. Moreover, exosomes also induced the expansion of CD8+ CD25+FoxP3+ T cell subset. Interestingly, despite cell decrease T. brucei seemed to increase FoxP3 molecules. Taken together, these findings indicate that parasite and parasite exosomes seem to have opposite effects on the evaluated cells. Parasites seem to minimize antigen presentation and avoid inducing the expansion of T cell subsets, facilitating its permanence in the host. On the other hand, T. brucei secreted exosomes seems to induce APC functions and mediate the expansion of Th lymphocytes, probably focusing the immune activity on the exosomes and not on the parasites. These findings allowed to understand some underlying principles of the innate and adaptive immune response in the early-stage of infection. Comprehension of these mechanisms can endorse the development of new strategies for control and elimination of African Trypanosomiasis
    • ‚Ķ
    corecore