12 research outputs found

    Extension des méthodes de traitement d'antenne au cas de fronts d'ondes arbitraires

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    La localisation de sources rayonnantes nécessite un modèle de propagation. Le plus communément utilisé est celui de fronts d'ondes plans et d'une antenne rectiligne à capteurs équidistants. Cependant, dans de nombreux cas en pratique, ce modèle est non conforme avec celui observé. Nous traitons dans cet article le cas de fronts d'ondes arbitraires (modules des capteurs inégaux-phases distordues). Nous exposons une technique qui exploite soit les deux sous-espaces source ou bruit, soit un partitionnement de la matrice spectrale et nous présentons des résultats obtenus avec des signaux d'acoustique sous-marine. Le champ d'application des méthodes de traitement d'antenne est alors étendu

    An update on the diagnosis and treatment of canine leishmaniosis caused by Leishmania infantum (syn. L. chagasi)

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    Canine leishmaniosis caused by Leishmania infantum is still a common disease in endemic areas, such as the Mediterranean countries, and has progressively expanded into non-endemic areas like Central and Northern Europe. The aim of this article is to critically review current knowledge on the diagnosis and treatment of this disease. In dogs with typical clinical signs and clinicopathological abnormalities, diagnosis is relatively easy based on the exclusion of major differentials, the demonstration of the parasite (e.g., with lymph node and/or skin cytology) and the presence of Leishmania-specific immunoglobulin G antibodies (quantitative serology). In less typical cases, these criteria together with the exclusion of possible differentials and the demonstration of compatible histological lesions in affected organs and tissues form the basis for a sound diagnosis. In clinically healthy dogs, molecular techniques are the most sensitive means for detecting L. infantum infection. Treatment of canine leishmaniosis should follow clinical staging and is usually based on meglumine antimonate or miltefosine administration for a few weeks in combination with allopurinol for several months. However, allopurinol monotherapy may be used in very mild cases as well as in dogs with end stage kidney disease. Aminosidine administered once daily at a revised dosage shows some promise but additional controlled studies are needed. Close attention to published guidelines regarding treatment and follow-up is necessary to achieve the best possible therapeutic outcome. (C) 2014 Elsevier Ltd. All rights reserved