The sources and interpretation of Olympic Law

In this article, Mark James and Guy Osborn discuss how the relationships between the various members of the Olympic Movement are governed by the Olympic Charter and the legal framework within which an edition of the Olympic Games is organised. The legal status of the Charter and its interpretation by the Court of Arbitration for Sport are examined to identify who is subject to its terms and how challenges to its requirements can be made. Finally, by using the UK legislation that has been enacted to regulate advertising and trading at London 2012, the far-reaching and sometimes unexpected reach of Olympic Law is explored

The Asymptotic Cone of Teichm\"uller Space: Thickness and Divergence

We study the Asymptotic Cone of Teichm\"uller space equipped with the Weil-Petersson metric. In particular, we provide a characterization of the canonical finest pieces in the tree-graded structure of the asymptotic cone of Teichm\"uller space along the same lines as a similar characterization for right angled Artin groups by Behrstock-Charney and for mapping class groups by Behrstock-Kleiner-Minksy-Mosher. As a corollary of the characterization, we complete the thickness classification of Teichm\"uller spaces for all surfaces of finite type, thereby answering questions of Behrstock-Drutu, Behrstock-Drutu-Mosher, and Brock-Masur. In particular, we prove that Teichm\"uller space of the genus two surface with one boundary component (or puncture) can be uniquely characterized in the following two senses: it is thick of order two, and it has superquadratic yet at most cubic divergence. In addition, we characterize strongly contracting quasi-geodesics in Teichm\"uller space, generalizing results of Brock-Masur-Minsky. As a tool, we develop a complex of separating multicurves, which may be of independent interest.Comment: This paper comprises the main portion of the author's doctoral thesis, 54 page

Monte Carlo Studies of the Fundamental Limits of the Intrinsic Hyperpolarizability

The off-resonant hyperpolarizability is calculated using the dipole-free sum-over-stats expression from a randomly chosen set of energies and transition dipole moments that are forced to be consistent with the sum rules. The process is repeated so that the distribution of hyperpolarizabilities can be determined. We find this distribution to be a cycloid-like function. In contrast to variational techniques that when applied to the potential energy function yield an intrinsic hyperpolarizability less than 0.71, our Monte Carlo method yields values that approach unity. While many transition dipole moments are large when the calculated hyperpolarizability is near the fundamental limit, only two excited states dominate the hyperpolarizability - consistent with the three-level ansatz.Comment: 7 pages, 5 figure

Reduced and declining physical function in prevalent dialysis patients – identifying the vulnerable

No abstract available

Stoat trap tunnel location : GIS predictive modelling to identify the best tunnel location : a thesis submitted in fulfillment of the requirements for the degree of Master of Philosophy in Geographic Information Systems in Massey University

Stoats are recognised as one of the biggest threats to New Zealand's threatened species. They are difficult to control because of their biological characteristics. Currently trapping is the most common type of control technique that has a proven success rate. Research studies have shown that some traps catch more stoats than others. However the reason for this is not well documented. The effectiveness of a trap set is difficult to determine because not all trap locations are the same and not all people have the same ability to select the best location for a trap. This study uses GIS to spatially analyse stoat capture data from a control operation on Secretary Island in conjunction with commonly available vegetation, habitat, diet and home range spatial data to see if there are consistent patterns that could be used as variables in a model that would predict the best place to locate a stoat trap tunnel. The model would then be tested against a similar dataset from Resolution Island. The Department of Conservation supplied the stoat capture data from the control operations on both islands. Standard spatial analysis techniques were used to generate surfaces that combined the capture data with the vegetation, habitat, diet and home range surfaces to produce predictive surfaces. The key finding from the research was that it is possible to produce a predictive model, although one was not created because the spatial datasets were not of a high enough resolution to provide conclusive evidence that could be confidently used as a variable in a model. The spatial analysis also indicated that stoats on both islands were caught mainly in the warmer northwestern parts of the islands although the study could not determine why there was a preference for these areas. In rugged terrain like that found on both islands the location of the track network will influence where the majority of stoats will be caught

NMR analysis of synthetic human serum albumin alpha-helix 28 identifies structural distortion upon amadori modification

The non-enzymatic reaction between reducing sugars and long-lived proteins in vivo results in the formation of glycation and advanced glycation end products, which alter the properties of proteins including charge, helicity, and their tendency to aggregate. Such protein modifications are linked with various pathologies associated with the general aging process such as Alzheimer disease and the long-term complications of diabetes. Although it has been suggested that glycation and advanced glycation end products altered protein structure and helicity, little structural data and information currently exist on whether or not glycation does indeed influence or change local protein secondary structure. We have addressed this problem using a model helical peptide system containing a di-lysine motif derived from human serum albumin. We have shown that, in the presence of 50 mM glucose and at 37 degrees C, one of the lysine residues in the di-lysine motif within this peptide is preferentially glycated. Using NMR analysis, we have confirmed that the synthetic peptide constituting this helix does indeed form a alpha-helix in solution in the presence of 30% trifluoroethanol. Glycation of the model peptide resulted in the distortion of the alpha-helix, forcing the region of the helix around the site of glycation to adopt a 3(10) helical structure. This is the first reported evidence that glycation can influence or change local protein secondary structure. The implications and biological significance of such structural changes on protein function are discussed

Quantizing the line element field

A metric with signature (-+++) can be constructed from a metric with signature (++++) and a double-sided vector field called the line element field. Some of the classical and quantum properties of this vector field are studied.Comment: 9 page