218 research outputs found

    Smit/Huizenhandel naar komend recht

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    Optimization of second harmonic generation and nonlinear phase-shifts in the Cerenkov regime

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    We present beam propagation method (BPM) studies of second harmonic generation (SHG) and nonlinear phaseshifts by cascading. The studies concentrate on SHG by means of radiation modes; the Cerenkov regime. The presented modeling does take into account both depletion and nonlinear phase shifts of the fundamental fields. BPM results show that leaky waves play an important role offering possibilities for enhancing the efficiency of SHG by orders of magnitude over general Cerenkov processes. Using a simple model and taking into account symmetry considerations, we identify the leaky modes that are important for the ¿(2)-processes in the structures that we investigate

    A Current Induced Transition in atomic-sized contacts of metallic Alloys

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    We have measured conductance histograms of atomic point contacts made from the noble-transition metal alloys CuNi, AgPd, and AuPt for a concentration ratio of 1:1. For all alloys these histograms at low bias voltage (below 300 mV) resemble those of the noble metals whereas at high bias (above 300 mV) they resemble those of the transition metals. We interpret this effect as a change in the composition of the point contact with bias voltage. We discuss possible explanations in terms of electromigration and differential diffusion induced by current heating.Comment: 5 pages, 6 figure

    Grated waveguide optical cavity for sensing

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    We demonstrate the versatility of a silicon nitride grated waveguide optical cavity as compact integrated optical sensors for (bulk) concentration detection, label-free protein sensing, and – with an integrated cantilever suspended above it – gas sensing

    Deceleration and trapping of heavy diatomic molecules using a ring-decelerator

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    We present an analysis of the deceleration and trapping of heavy diatomic molecules in low-field seeking states by a moving electric potential. This moving potential is created by a 'ring-decelerator', which consists of a series of ring-shaped electrodes to which oscillating high voltages are applied. Particle trajectory simulations have been used to analyze the deceleration and trapping efficiency for a group of molecules that is of special interest for precision measurements of fundamental discrete symmetries. For the typical case of the SrF molecule in the (N,M) = (2, 0) state, the ring-decelerator is shown to outperform traditional and alternate-gradient Stark decelerators by at least an order of magnitude. If further cooled by a stage of laser cooling, the decelerated molecules allow for a sensitivity gain in a parity violation measurement, compared to a cryogenic molecular beam experiment, of almost two orders of magnitude

    Effect of high-dose dexamethasone on perioperative lactate levels and glucose control: A randomized controlled trial

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    Introduction: Blood lactate levels are increasingly used to monitor patients. Steroids are frequently administered to critically ill patients. However, the effect of steroids on lactate levels has not been adequately investigated. We studied the effect of a single intraoperative high dose of dexamethasone on lactate and glucose levels in patients undergoing cardiac surgery. Methods: The Dexamethasone for Cardiac Surgery (DECS) trial was a multicenter randomized trial on the effect of dexamethasone 1 mg/kg versus placebo on clinical outcomes after cardiac surgery in adults. Here we report a pre-planned secondary analysis of data from DECS trial participants included at the University Medical Center Groningen. The use of a computer-assisted glucose regulation protocol-Glucose Regulation for Intensive care Patients (GRIP
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