Review of the development of small- and medium-capacity gas turbines at the Motoren- und Turbinen Union

Small- and medium-capacity gas turbines under development for turboprop aircraft and helicopter, as well as for armored and commercial vehicle propulsion, are discussed. Design problems related to axial turbines, ceramic components, regenerative gas turbines, and the optimal expansion ratios for turbines with capacities from 250 to greater than 800 kW are considered; in addition, combustion chamber technology is mentioned. Prototype gas turbines with capacities of 500 to 600 kW or 800 to 1800 kW are described

Rapid reversion from monomer to dimer regenerates the ultraviolet-B photoreceptor UV RESISTANCE LOCUS8 in intact arabidopsis plants

Arabidopsis (Arabidopsis thaliana) UV RESISTANCE LOCUS8 (UVR8) is a photoreceptor that specifically mediates photomorphogenic responses to ultraviolet (UV)-B in plants. UV-B photoreception induces the conversion of the UVR8 dimer into a monomer that interacts with the CONSTITUTIVELY PHOTOMORPHOGENIC1 (COP1) protein to regulate gene expression. However, it is not known how the dimeric photoreceptor is regenerated in plants. Here, we show, by using inhibitors of protein synthesis and degradation via the proteasome, that the UVR8 dimer is not regenerated by rapid de novo synthesis following destruction of the monomer. Rather, regeneration occurs by reversion from the monomer to the dimer. However, regeneration of dimeric UVR8 in darkness following UV-B exposure occurs much more rapidly in vivo than in vitro with illuminated plant extracts or purified UVR8, indicating that rapid regeneration requires intact cells. Rapid dimer regeneration in vivo requires protein synthesis, the presence of a carboxyl-terminal 27-amino acid region of UVR8, and the presence of COP1, which is known to interact with the carboxyl-terminal region. However, none of these factors can account fully for the difference in regeneration kinetics in vivo and in vitro, indicating that additional proteins or processes are involved in UVR8 dimer regeneration in vivo

Common-reflection-surface imaging of shallow and ultrashallow reflectors

We analyzed the feasibility of the common-reflection-surface (CRS) stack for near-surface surveys as an alternative to the conventional common midpoint (CMP) stacking procedure. The data-driven, less user-interactive CRS method could be more cost efficient for shallow surveys, where the high sensitivity to velocity analysis makes data processing a critical step. We compared the results for two field data sets collected to image shallow and ultrashallow reflectors: an example of shallow Pwave reflection for targets in the first few hundred meters, and an example of SH-wave reflection for targets in the first 10 m. By processing the shallow P-wave records using the CMP method, we imaged several nearly horizontal reflectors with onsets from 60 to about 250 ms. The CRS stack produced a stacked section more suited for a subsurface interpretation, without any preliminary formal and time-consuming velocity analysis, because the imaged reflectors possessed greater coherency and lateral continuity. With CMP processing of the SHwave records, we imaged a dipping bedrock interface below four horizontal reflectors in unconsolidated, very low velocity sediments. The vertical and lateral resolution was very high, despite the very shallow depth: the image showed the pinchout of two layers at less than 10 m depth. The numerous traces used by the CRS stack improved the continuity of the shallowest reflector, but the deepest overburden reflectors appear unresolved, with not well-imaged pinchouts. Using the kinematic wavefield attributes determined for each stacking operation, we retrieved velocity fields fitting the stacking velocities we had estimated in the CMP processing. The use of CRS stack could be a significant step ahead to increase the acceptance of the seismic reflection method as a routine investigation method in shallow and ultrashallow seismics

Multicriticality of the (2+1)-dimensional gonihedric model: A realization of the (d,m)=(3,2) Lifshitz point

Multicriticality of the gonihedric model in 2+1 dimensions is investigated numerically. The gonihedric model is a fully frustrated Ising magnet with the finely tuned plaquette-type (four-body and plaquette-diagonal) interactions, which cancel out the domain-wall surface tension. Because the quantum-mechanical fluctuation along the imaginary-time direction is simply ferromagnetic, the criticality of the (2+1)-dimensional gonihedric model should be an anisotropic one; that is, the respective critical indices of real-space (\perp) and imaginary-time (\parallel) sectors do not coincide. Extending the parameter space to control the domain-wall surface tension, we analyze the criticality in terms of the crossover (multicritical) scaling theory. By means of the numerical diagonalization for the clusters with N\le 28 spins, we obtained the correlation-length critical indices (\nu_\perp,\nu_\parallel)=(0.45(10),1.04(27)), and the crossover exponent \phi=0.7(2). Our results are comparable to (\nu_{\perp},\nu_{\parallel})=(0.482,1.230), and \phi=0.688 obtained by Diehl and Shpot for the (d,m)=(3,2) Lifshitz point with the \epsilon-expansion method up to O(\epsilon^2)

Morphine Metabolism in Human Skin Microsomes

For patients with severe skin wounds, topically applied morphine is an option to induce efficient analgesia due to the presence of opioid receptors in the skin. However, for topical administration it is important to know whether the substance is biotransformed in the skin as this can eventually reduce the concentration of the active agent considerably. We use skin microsomes to elucidate the impact of skin metabolism on the activity of topically applied morphine. We are able to demonstrate that morphine is only glucuronidated in traces, indicating that the biotransformation in the skin can be neglected when morphine is applied topically. Hence, there is no need to take biotransformation into account when setting up the treatment regimen. Copyright (C) 2012 S. Karger AG, Base

Carbocationic cyclisations and rearrangements in the damascone series

A regio- and stereoselective synthesis of the tertiary chloride 7 is described, involving the Lewis acid catalysed addition of the allyl chloride 6 to isobutene as a key step. Acid catalysed cyclisation of 7 yields the damasconoid compounds 12–15