95 research outputs found

    A review of species of the genus Mocyta (Coleoptera, Staphylinidae) in Ukraine

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    A review of the genus Mocyta Mulsant & Rey, 1874, which is represented in Ukraine; a description of the main morphological features and diagnostic features is made, data on ecological features, seasonal activity of adults, the distribution of representatives of the genus in Ukraine and the world and the keys to identify the species are presented. The information on the distribution of species of the genus Mocyta in the territory of Ukraine has been clarified and significantly supplemented by new findings. The results can be used to address a number of theoretical issues of faunistics, zoogeography, and ecology, as well as in compiling the inventory of the fauna of the Ukrainian Carpathians, for comparative faunal research, in the analysis of species distribution, in biogeographic constructions, studies of faunogenesis, ecological monitoring and prediction of consequences of the influence of human activities on natural ecosystems of the region. The genus Mocyta is a widespread genus, which in terms of the combination of morphological and biological features belongs to the tribe Athetini Casey, 1910 of the subfamily Aleocharinae Fleming, 1821 of the family Staphylinidae Latreille, 1802. There are 26 known species in the fauna of Palearctic, 5 of which (Mocyta clientula, M. fungi fungi, M. fussi, M. orbata, M. orphana) are represented in the fauna of Ukraine. However, it is likely that there are two more species (M. amplicollis and M. negligens), identified for the surrounding areas, for which characteristics and comparative diagnoses have also been provided. This paper is a continuation of the initiated series of reviews of genera and species of the tribe Athetini of the fauna of Ukraine. Taking into account the wide geographical distribution and significant individual variability in size, colour and shape of the spermatheca of representatives of the genus, the identification of the latter presents some significant difficulties

    Aseguramiento de protecci贸n contra el fuego en complejos industriales de agrupaciones animales

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    Aqu铆 se presenta el estudio del aseguramiento de la protecci贸n contra el fuego en edificios agrupados de un conjunto de ganader铆a por medio de optimizar las medidas legislativas respectivas y analizar las influencias en la calidad y fiabilidad de los resultados de evaluar riesgos de incendio. Se llevaron a cabo los estudios a trav茅s de hacer valoraci贸n profesional, calcular riesgos de incendio individuales y simular la evacuaci贸n de la gente en el modelo de flujos humanos individual y en cadena. Los aspectos funcionales conceptuales de los edificios del conjunto resultaron en la necesidad de desarrollar soluciones t茅cnicas y estructurales que podr铆an ayudar a reducir gastos ineficientes y armonizar铆an los edificios con las exigencias de la protecci贸n contra el fuego. El riesgo de incendios individual para los trabajadores del objeto de protecci贸n considerado es 2.91x10-7 por a帽o-1 (0.291x10-6 por a帽o), es decir, no sobrepasa el nivel normal establecido por la ley Federal 123-FZ del 22 de Julio de 2008 芦Regulaciones T茅cnicas de las Exigencias a la Protecci贸n contra el Fuego". La adopci贸n en el nivel legislativo del sistema de valorar riesgos de incendio cre贸 para los due帽os de objetos la oportunidad de optimizar los gastos para asegurar la protecci贸n contra el fuego, incluyendo el aseguramiento del nivel exigido de seguridad human

    Aseguramiento de protecci贸n contra el fuego en complejos industriales de agrupaciones animales

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    This study deals with ensuring fire safety in buildings of a cluster animal industrial complex by optimizing legislative measures and analyzing factors that affect the quality and reliability of the results of calculating fire risk. The research involved the following methods: expert assessment; calculating individual fire risk; modeling evacuation of people in the form of an individual flow model of human traffic. The conceptual features of the complex's buildings required developing the design and technical solutions that would reduce inefficient costs on the one hand, and, on the other, would ensure meeting fire safety requirements. The individual fire risk for employees of the asset to be protected is 2.91 脳10-7 per year-1 (0.291 脳10-6 per year). That is, it does not exceed the characteristic value established by Federal law No. 123-FZ dated 22.07.2008 'Technical regulations on fire safety'. After the introduction of the fire risk assessment system at the legislative level, the owners of objects have received the opportunity to optimize the cost of fire safety and the required level of human safety.Aqu铆 se presenta el estudio del aseguramiento de la protecci贸n contra el fuego en edificios agrupados de un conjunto de ganader铆a por medio de optimizar las medidas legislativas respectivas y analizar las influencias en la calidad y fiabilidad de los resultados de evaluar riesgos de incendio. Se llevaron a cabo los estudios a trav茅s de hacer valoraci贸n profesional, calcular riesgos de incendio individuales y simular la evacuaci贸n de la gente en el modelo de flujos humanos individual y en cadena. Los aspectos funcionales conceptuales de los edificios del conjunto resultaron en la necesidad de desarrollar soluciones t茅cnicas y estructurales que podr铆an ayudar a reducir gastos ineficientes y armonizar铆an los edificios con las exigencias de la protecci贸n contra el fuego. El riesgo de incendios indivudual para los trabajadores del objeto de protecci贸n considerado es 2.91x10-7 por a帽o-1 (0.291x10-6 por a帽o), es decir, no sobrepasa el nivel normal establecido por la ley Federal 123-FZ del 22 de Julio de 2008 芦Regulaciones T茅cnicas de las Exigencias a la Protecci贸n contra el Fuego禄. La adopci贸n en el nivel legislativo del sistema de valorar riesgos de incendio cre贸 para los due帽os de objetos la oportunidad de optimizar los gastos para asegurar la protecci贸n contra el fuego, incluyendo el aseguramiento del nivel exigido de seguridad humana

    Fluctuating Asymmetry of Measurable Parameters in Rana arvalis : Methodology

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    72 Fluctuating asymmetry (FA), i.e., undirected deviations from bilateral symmetry, of both measurable and nonmeasurable characteristics reflects ontogenetic instability, which some authors believe increases in response to genomic or environmental stress. This allows FA to be used for estimating the state of anthropogenically affected natural populations (e.g., Rana arvalis young of the year were captured on August 4 and 5, 2003, in the Kalinovskie Razrezy Park Forest in northern Yekaterinburg ( n = 26) and near the Yuzhnaya Bus Terminal ( n = 15), respectively. Ponds existing in the park forest had resulted from flooding desolate quarries. The vegetation was a herb-grass pine forest containing small shrubs. The results of our hydrochemical analyses performed in 2003 indicate that, according to the ecological sanitary classification of the quality of surface waters suggested by We measured the size parameters of the body that are standard for amphibians The results of the measurements shown in the table indicate that storage in the fixative led to a slight decrease in the mean values of most parameters measured in frogs from both populations. This decrease was the largest (and statistically significant) for the lengths of the thigh, crus, and temporal spot, i.e., the measurements at least partly involving soft tissue (F = 11.13-144.32, d.f. = 1/25 or 1/14, P = 0.004-0.0001 for the results of ANOVA with factors individual, body side

    Secretory phospholipase A2: a biomarker of inflammation in autoimmune, bacterial and viral diseases

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    Secretory phospholipases A2 (sPLA2) represent a large superfamily of enzymes with a molecular weight of 14-19 kDa, including 15 groups and more than 30 isoforms belonging to four types: secretory (sPLA2), cytosolic (cPLA2), calcium-independent (iPLA2) and lipoprotein-associated phospholipase A2 (LP-PLA2, PAF-AH). Eleven species of secretory sPLA2s (IB, IIA, IIC, IID, IIE, IIF, III, V, X, XIIA, and XIIB) have been found in mammals, performing versatile functions and participating in the pathogenesis of a wide range of diseases. On the one hand, sPLA2 may promote elimination of damaged, apoptotic cells by hydrolyzing membrane phospholipids, and exerts a strong bactericidal and antiviral properties, including pronounced effects against antibiotic-resistant strains of microorganisms. In this regard, the use of sPLA2 may represent a new strategy for the treatment of bacterial and viral infections. Moreover, due to the action of sPLA2 on its substrates, a number of biologically active molecules (arachidonic, lysophosphatidic acids, lysophospholipids, fatty acids, prostaglandins, leukotrienes, thromboxanes) are formed, which provide strong inflammatory, detergent, coagulating effects and increase vascular permeability. This pro-inflammatory role of sPLA2 may explain its increase levels and activity in cardiovascular, respiratory, autoimmune, metabolic, oncological, bacterial and viral disorders. The review article presents a classification of sPLA2 isoforms, their substrates, regulatory factors, biological significance, and mechanisms of their strong bactericidal, virucidal, and pro-inflammatory activity in the heart and lung disorders, autoimmune, metabolic, bacterial, and viral diseases. In particular, the mechanisms of the selective action of sPLA2 against Gram-positive and Gram-negative microorganisms are discussed. We consider diagnostic and prognostic significance, correlations between elevated levels and activity of sPLA2 and distinct clinical symptoms, severity and outcome in the patients with coronary heart disease (CAD), acute myocardial infarction (AMI), atherosclerosis, acute inflammatory lung injury (ALI), respiratory distress syndrome (ARDS), chronic obstructive pulmonary disease (COPD), rheumatoid arthritis, bronchial asthma, bacterial infections, septicemia and viral (COVID-19) infections. The opportunity of using sPLA2 as a biomarker of the severity and outcome of patients with chronic obstructive pulmonary disease, bacterial infections, sepsis and viral infections, including COVID-19, is also considered

    Surgical Treatment of Stenosis of Spinal Canal and Dural Sac at the Craniovertebral Junction

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    The paper presents the results of surgical treatment of 12 patients with stenosing processes of the vertebral canal at the craniovertebral transition due to chronic, unstable type 2 injuries of the C odontoid process (classification of fractures of odontoid process proposed in 1974 by Anderson and D鈥橝lonzo). Patient examination included clinical-neurologic examination, review spondylograms of the cervical spine in 2 projections, MSCT, MRI. All patients were admitted to the clinic with external fixators (cervical support collar or Philadelphia collar). In the preoperative period, all patients were divided into 2 groups according to indications and contraindications for the application of the HALO-device. The first group consisted of 7 people, with cervical spine still fixed with the cervical support collar or Philadelphia collar, and the second group consisted of 5 patients with CII fracture fixed and corrected in the preoperative period by the HALO-device. All patients underwent surgical intervention 鈥 posterior approach decompression of the spinal canal and dural sack in the craniovertebral passage by CI laminectomy, partial resection of the posterior margin of the occipital aperture followed by the implementation of atlanto-axial occipitospondylodesis (a clamp with shape-memory effect for posterior occipitospondylodesis, OOO 鈥淢ITS SPF鈥, Novokuznetsk, Russia). A comparative analysis of the results of surgical treatment of posttraumatic stenoses of the vertebral canal with and without the use of the HALO-traction device was performed. The results was better in the second group, which makes it possible to consider the second variant of surgical treatment more pathogenetically justified. Thus, HALO-traction restors anatomo-topographic relationships in the craniovertebral zone creating hard external fixation, helping to avoid intraoperative complications

    On the results of the Second Scientific Forum 鈥淕enetic Resources of Russia鈥

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    The Second Scientific Forum 鈥淕enetic Resources of Russia鈥 was held in St. Petersburg, June 26-28, 2023. Th械 Forum comprised nine associated scientific conferences and conference schools dedicated to the establishment, formation, conservation, development, studying and utilization of biological (bioresource) collections as well as to the activities of bioresource centers, and a round table entitled 鈥淪tatutory Legal Regulation and Standards for the Work with Bioresource Collections鈥. More than 700 researchers representing over a hundred scientific institutions and universities from Russia and other countries participated in the Forum. In total, more than 200 oral presentations were made during those events (including 16 talks at the Forum鈥檚 Plenary Session). The participants of the Forum events thoroughly discussed the results of the Federal Scientific and Technical Program for the Development of Genetic Technologies for 2019-2030 associated with the establishment and development of bioresource collections for research in the field of genetic technologies, the prospects for the promotion of this sector, and the regulatory legal framework in the sphere of ensuring conservation and development of biological (bioresource) collections, establishment and functioning of bioresource centers, and their sustainable and rational utilization in scientific research and development activities. The outcome of those discussions is presented in this publication in the form of the Forum鈥檚 Resolution. Upon reviewing the results of the Federal Scientific and Technical Program for the Development of Genetic Technologies for 2019-2030 pertaining to the establishment and development of bioresource collections for research in the field of genetic technologies, the Forum recognized them as successful. The Forum approved the draft of the legal act 鈥淥n Bioresource Centers and Biological (Bioresource) Collections鈥, which is currently under consideration in the State Duma of the Russian Federation and emphasized the need for its soonest adoption

    On the results of the First Scientific Forum 芦Genetic Resources of Russia禄: prospects for development, research and practical potential of bio-collections

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    Nine separate scientific conferences and school-conferences dedicated to the conservation, development, study and practical use of biological collections of various types were held under the auspices of the First Scientific Forum 鈥淕enetic Resources of Russia鈥, which took place in Saint Petersburg on 21-24 June 2022. A total of more than 300 oral presentations were made at these events. The Forum plenary sessions, which included 25 lectures, attracted more than 1,500 participants. The development prospects, research and scientific-practical potential of biological collections were thoroughly discussed at the events of the Forum. The results of these discussions are presented in this publication in the form of a Forum resolution. The strategic role of biological collections for the conservation of genetic diversity, for the scientific and technological development of society and for the provision of educational processes is emphasized. This strategic framework, which should be developed and maintained, also makes it possible to implement practical tasks related to meeting the challenges in the field of food and environmental security, health care and technological independence in the rapidly developing spheres of the economy

    Identification of Novel Candidate Markers of Type 2 Diabetes and Obesity in Russia by Exome Sequencing with a Limited Sample Size

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    Type 2 diabetes (T2D) and obesity are common chronic disorders with multifactorial etiology. In our study, we performed an exome sequencing analysis of 110 patients of Russian ethnicity together with a multi-perspective approach based on biologically meaningful filtering criteria to detect novel candidate variants and loci for T2D and obesity. We have identified several known single nucleotide polymorphisms (SNPs) as markers for obesity (rs11960429), T2D (rs9379084, rs1126930), and body mass index (BMI) (rs11553746, rs1956549 and rs7195386) (p < 0.05). We show that a method based on scoring of case-specific variants together with selection of protein-altering variants can allow for the interrogation of novel and known candidate markers of T2D and obesity in small samples. Using this method, we identified rs328 in LPL (p = 0.023), rs11863726 in HBQ1 (p = 8 × 10−5), rs112984085 in VAV3 (p = 4.8 × 10−4) for T2D and obesity, rs6271 in DBH (p = 0.043), rs62618693 in QSER1 (p = 0.021), rs61758785 in RAD51B (p = 1.7 × 10−4), rs34042554 in PCDHA1 (p = 1 × 10−4), and rs144183813 in PLEKHA5 (p = 1.7 × 10−4) for obesity; and rs9379084 in RREB1 (p = 0.042), rs2233984 in C6orf15 (p = 0.030), rs61737764 in ITGB6 (p = 0.035), rs17801742 in COL2A1 (p = 8.5 × 10−5), and rs685523 in ADAMTS13 (p = 1 × 10−6) for T2D as important susceptibility loci in Russian population. Our results demonstrate the effectiveness of whole exome sequencing (WES) technologies for searching for novel markers of multifactorial diseases in cohorts of limited size in poorly studied populations

    Diagnostic and Treatment Errors in Biliary Cystadenomas and Cystadenocarcinomas: Clinical Cases

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    Background. Biliary cystadenomas and cystadenocarcinomas are rare cystic tumors of the liver. Complicated differential diagnostics for simple cysts often leads to errors in surveillance of patients with these tumors. Cystadenoma and cystadenocarcinoma should be suspected upon detection of single or multilocular cystic neoplasms of the liver with septa and blood flow loci聽 in the cyst wall, especially in middle-aged women. The localization of the tumor is critical. The most common localization is segment IV of the liver. Urgent intraoperative biopsy is required to determine the extent of surgery.Case description. Clinical observations with analysis of the examination and treatment data of two female patients aged 38 and 56 were presented. Both clinical observations illustrate the underestimation of the preoperative examination data that served as a ground for diagnosis of liver cysts with inadequate extent of surgery. In the first case, the resection was incomplete, and, as such, the biliary cystadenoma recurred in the resection area, the capsule of the neoplasm was ruptured and an encysted fluid collection was formed. In the second case, lack of histological examination of the excised neoplasm, due to confidence in its morphological verification as a cyst, resulted in cystadenoma recurrence in the resection zone with metastasis to the contralateral lobe of the liver.Conclusion. Hepatic cystadenomas and cystadenocarcinomas are often misdiagnosed as simple cysts. These tumors should be suspected in central localization of the tumor in the liver, especially in young women. The clinical and instrumental symptomatology and radiological semiotics of the disease require careful evaluation. The recurrence of a cystic lesion in the resection zone in a patient previously operated for a hepatic cyst serves as an additional signal for detecting biliary cystadenoma. Rational strategy for surgical management of cystic liver lesions should include hepatectomy within healthy tissues (both anatomical and atypical) with mandatory intraoperative ultrasound and urgent histological examinations
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