18 research outputs found

    Origin and number of frogs used for mtDNA analysis

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    Populations, geographic coordinates and sample sizes of samples used for mtDNA analysis. The column ‚ÄúMicrosat No.*‚ÄĚ refers to the numbering of populations in Table S1 (new), where only populations used in microsatellite analyses are listed. Types of mtDNA are abbreviated as follows: les = lessonae-type, rid = ridibundus-type, ber = bergeri-type, cf. bed = cf. bedriagae-type

    Genetic structure within the R and L genome

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    Genetic differentiation within the R and L genome of water frogs of the Pelophylax esculentus complex, according to Bayesian analyses implemented in the program STRUCTURE. The proportion of membership (parameter q according to Pritchard et al. 2000) of each individual in each of the two (R genome) and four (L genome) inferred clusters is shown

    Origin and number of frogs used for mtDNA analysis

    No full text
    Populations, geographic coordinates and sample sizes of samples used for mtDNA analysis. The column ‚ÄúMicrosat No.*‚ÄĚ refers to the numbering of populations in Table S1 (new), where only populations used in microsatellite analyses are listed. Types of mtDNA are abbreviated as follows: les = lessonae-type, rid = ridibundus-type, ber = bergeri-type, cf. bed = cf. bedriagae-type

    Treatment of NB cells with R1507 or PIK75 in presence of chemotherapy results in additive effects.

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    <p>NB cells grown in serum-containing medium were incubated with the IGF-1R antibody R1507 (0.1 őľg/ml) (A) or the PI3K inhibitor PIK75 (0.05 őľM) (B+C) in presence or absence of cisplatin (1 őľM), etoposide (1 őľM), or doxorubicin (0.1 őľM). Cell proliferation was assessed using the MTS assay after 48 h. The data represent the mean of 8 replicates with SD from 3 independent experiments. (*p<0.05).</p

    Additive/sensitization effects after combinatorial treatment with R1507 and chemotherapy in MB cells.

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    <p>The MB cell lines PFSK (A), UW228 (B) and DAOY (C) grown in serum-containing medium were incubated with increasing concentrations of cisplatin in presence or absence of the IGF-1R antibody R1507 (25 ¬Ķg/ml or 50 ¬Ķg/ml). Cell proliferation was assessed using the MTS assay after 48 h. The data represent the mean of 6 replicates with SD from 3 independent experiments.</p

    The effect of R1507 on cell proliferation of NB and MB cells.

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    <p>A panel of NB cell lines (A) and MB cell lines (B) were incubated with increasing concentrations of the antibody R1507 inhibiting the IGF-1R in serum-containing medium. Cell viability was assessed using the MTS assay after 2 days. The data represent the mean with SD from at least 6 replicates and 3 independent experiments.</p
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