2,081 research outputs found
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Life in Martian snows – measurements of UV protection under natural Antarctic snows in the UVC (254 nm)
The habitability of the Universe through 13 billion years of cosmic time
The field of astrobiology has made tremendous progress in modelling
galactic-scale habitable zones which offer a stable environment for life to
form and evolve in complexity. Recently, this idea has been extended to
cosmological scales by studies modelling the habitability of the local Universe
in its entirety (e.g. Dayal et al. 2015; Li & Zhang 2015). However, all of
these studies have solely focused on estimating the potentially detrimental
effects of either Type II supernovae (SNII) or Gamma Ray Bursts (GRBs),
ignoring the contributions from Type Ia supernovae (SNIa) and active galactic
nuclei (AGN). In this study we follow two different approaches, based on (i)
the amplitude of deleterious radiation and (ii) the total planet-hosting volume
irradiated by deleterious radiation. We simultaneously track the contributions
from the key astrophysical sources (SNII, SNIa, AGN and GRBs) for the entire
Universe, for both scenarios, to determine its habitability through 13.8
billion years of cosmic time. We find that SNII dominate the total radiation
budget and the volume irradiated by deleterious radiation at any cosmic epoch
closely followed by SNIa (that contribute half as much as SNII), with GRBs and
AGN making up a negligible portion (<1%). Secondly, as a result of the total
mass in stars (or the total number of planets) slowly building-up with time and
the total deleterious radiation density, and volume affected, falling-off after
the first 3 billion years, we find that the Universe has steadily increased in
habitability through cosmic time. We find that, depending on the exact model
assumptions, the Universe is 2.5 to 20 times more habitable today compared to
when life first appeared on the Earth 4 billion years ago. We find that this
increase in habitability will persist until the final stars die out over the
next hundreds of billions of years.Comment: Under refereeing in Ap
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Endolithic colonization of fluid inclusion trails in mineral grains
Many scenarios for the colonization of planetary surfaces by microbial life involve endoliths. This study records microbial mass along fluid inclusion trails (healed microfractures) in quartz grains
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Life in polar impact-shocked rocks — an analog for micro-habitats at the Martian poles
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Gullies on Mars: Origin by snow and ice melting and potential for life based on possible analogs from Devon Island, High Arctic
Gullies on Devon Island, High Arctic, which form by melting of transient surface ice and snow covers and offer morphologic and contextual analogs for gullies reported on Mars are reported to display enhancements in biological activity in contrast to surrounding polar desert terrain
Deep sequencing approaches for the analysis of prokaryotic transcriptional boundaries and dynamics
The identification of the protein-coding regions of a genome is straightforward due to the universality of start and stop codons. However, the boundaries of the transcribed regions, conditional operon structures, non-coding RNAs and the dynamics of transcription, such as pausing of elongation, are non-trivial to identify, even in the comparatively simple genomes of prokaryotes. Traditional methods for the study of these areas, such as tiling arrays, are noisy, labour-intensive and lack the resolution required for densely-packed bacterial genomes. Recently, deep sequencing has become increasingly popular for the study of the transcriptome due to its lower costs, higher accuracy and single nucleotide resolution. These methods have revolutionised our understanding of prokaryotic transcriptional dynamics. Here, we review the deep sequencing and data analysis techniques that are available for the study of transcription in prokaryotes, and discuss the bioinformatic considerations of these analyses
Misincorporation by RNA polymerase is a major source of transcription pausingin vivo
The transcription error rate estimated from mistakes in end product RNAs is 10−3–10−5. We analyzed the fidelity of nascent RNAs from all actively transcribing elongation complexes (ECs) in Escherichia coli and Saccharomyces cerevisiae and found that 1–3% of all ECs in wild-type cells, and 5–7% of all ECs in cells lacking proofreading factors are, in fact, misincorporated complexes. With the exception of a number of sequence-dependent hotspots, most misincorporations are distributed relatively randomly. Misincorporation at hotspots does not appear to be stimulated by pausing. Since misincorporation leads to a strong pause of transcription due to backtracking, our findings indicate that misincorporation could be a major source of transcriptional pausing and lead to conflicts with other RNA polymerases and replication in bacteria and eukaryotes. This observation implies that physical resolution of misincorporated complexes may be the main function of the proofreading factors Gre and TFIIS. Although misincorporation mechanisms between bacteria and eukaryotes appear to be conserved, the results suggest the existence of a bacteria-specific mechanism(s) for reducing misincorporation in protein-coding regions. The links between transcription fidelity, human disease, and phenotypic variability in genetically-identical cells can be explained by the accumulation of misincorporated complexes, rather than mistakes in mature RNA
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Microbial preservation in sulfates in the Haughton impact structure suggests target in search for life on Mars
Microbes occur within transparent gypsum crystals in the Haughton crater. The crystals transmit light for photosynthesis, but protect from dehydration and wind. Sulfates on the Martian surface should be a priority target in the search for life
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Ultraviolet protection on a snowball Earth
Habitats in the Antarctic provide an insight into habitats available on snowball earth. Physical UV protection on snowball earth would have been dominated by the manifestations of ice and snow in different habitats. The snowball period was a golden age of UV protection
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