4 research outputs found

    Relationship between appetite and symptoms of depression and anxiety in patients on chronic hemodialysis

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    We aimed at evaluating the association between appetite and symptoms of depression and anxiety, cognitive dysfunction, fatigue, and comorbidities in patients on hemodialysis (HD)

    Mini Mental State Examination over time in chronic hemodialysis patients

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    Cognitive impairment is relatively common in end-stage renal disease patients on chronic hemodialysis, but the course of cognitive function deterioration in hemodialysis patients is essentially unknown. The present study aimed to evaluate if changes in Mini Mental State Examination (MMSE) over time in hemodialysis (HDP) and elderly (EP) patients differ significantly and determine the variables associated with such possible changes

    Symptoms of depression and anxiety over time in chronic hemodialysis patients

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    Background: Little is known about the course of the symptoms of depression/anxiety and the factors predictive of such courses in hemodialysis (HD) patients. This study aimed at evaluating the possible changes of Beck Depression Inventory (BDI) and Hamilton Anxiety Rating Scale (HARS) over time, and factors associated with such changes in HD patients. Methods: We screened 110 patients for study participation. Of these, 30 were excluded because of dialytic vintage 14 and 38 patients <=14. In patients with BDI <=14, the BDI decreased/remained stable in 19 and increased in 19. Patients with increased BDI had lower baseline MMSE (22.6 \ub1 2.6 vs. 25.9 \ub1 2.7, p=0.004) and higher baseline serum CRP (6.07 \ub1 4.2 vs. 1.64 \ub1 1.59, p=0.003). At multivariate analysis the relationship between BDI changes and MMSE and serum CRP was statistically significant. In 25 patients, the HARS decreased/remained stable, while in 13 it increased. Characteristics of the 2 groups of patients did not differ significantly. Conclusions: In a meaningful proportion of HD patients, symptoms of depression worsen over time, and CRP and MMSE are independent predictors of such change
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