One- Pot synthesis and reactions of Novel 5-(4-fluoro-phenyl)-3-(8-hydroxyquinolin-5- yl)-7-phenyl-5H-thiazolo[3,2-a]pyrimidine-6- carbonitrile as antimicrobial agents

The synthesis of 5-(4-fluoro-phenyl)-3-(8-hydroxyquinolin-5-yl)-7-phenyl-5H-thiazolo[3,2-a]pyrimidine-6-carbonitrile 4 was achieved by one-potthree-component synthesis using p-TSA (10 mol %) in refluxing CH3CN. Compound 4 was utilized tosynthesize a new series of thiazolo[3,2-a]pyrimidines6-8, [1,2,4]triazolo[3,4-b][1,3,4]thiadiazoles 10, 11a-c and 12a-c. Also, derivatives of Schiff bases 13a-c of compound 9 were obtained by the treatment with some aromatic aldehydes. The latter compounds under went Mannich reaction with morpholin to afford the N-morpholinomethyl- amino derivatives 14a-c. The structures of the new compounds are supported by FT IR, 1H NMR, 13 CNMR, Mass spectroscopy and elemental analysis. All newly synthesized compounds were screened for their antimicrobial activity

Perceptions on the usefulness of published financial information to the Egyptian capital marker

The main objective of this study is to investigate empirically users' perceptions of the usefulness of financial information that could be provided in corporate annual reports presented by listed companies in Egypt. This investigation is carried out, in the light of the requirements of the Egyptian Accounting Standards (EASs) issued in 1997, the new listing rules of the Cairo and Alexandria Stock Exchange (CASE) adopted in 2000 and the Capital Market Law (CML) No. 95/1992, using a set of eleven qualitative characteristics of accounting information (QCOAI) in a hierarchy, which should be possessed by financial information if it is to be useful to its users. Those characteristics are: understandability, relevance, reliability, comparability, predictive value, timeliness, faithful representation, neutrality, verifiability, consistency and materiality. A survey was carried out, based on a questionnaire, which was designed and pre-tested in two stages, as a basic data collection instrument supported by some semi-structured personal interviews. 320 questionnaires were personally distributed, and a total of 232 questionnaires were collected. Of them 222 were usable and analysable, representing about 69.38%. The survey was conducted to examine the perceptions of five groups of users of corporate annual reports, namely, financial analysts, decision makers, academics, stock brokers, and staff of the regulatory and observatory bodies, regarding the importance they attach to corporate annual reports and different sources of financial information, sections of corporate annual reports, each of the QCOAI selected earlier in the study, and some financial information items. The collected data were largely quantifiable and based on a five-point scale. The Statistical Package for Social Sciences — SPSS was used in analysing the collected data and the analysis was carried out for the overall sample and for the various sub-groups using the descriptive statistics and the statistical analysis (the non-parametric tests such as the Chi-square Test, the Kruskal-Wallis H Test and the Mann-Whitney U Test). A major finding is that "corporate annual reports" were perceived as the most important source of financial information by users in Egypt, followed by "newspapers and magazines" and "the direct contact with the company management". Also, there was a clear finding that "income statement" was considered as the most important section among the various sections of corporate annual reports followed by "balance sheet" and "cash flow statement". It was found that users as a whole, and as occupation, education and experience groups, considered the selected set of QCOAI to be suitable for use in the evaluation of the usefulness of financial information provided in corporate annual reports. All selected characteristics were perceived to be important or very important characteristics, to slightly different degrees. Furthermore, the study found that "timeliness" was considered as the most important characteristic. Lastly, the majority of financial information items that were perceived as the most important items, whether or not mandatorily required, are not disclosed by listed companies

The Impact of organizational Learning Culture's on Job Satisfaction, Organizational Commitment, and Turnover Intention among Privet sector in Saudi Arabia

Organizational learning culture has positive impact with job satisfaction on the productivity of the organization, this study showed that there is a negative relationship between the organizational learning culture and turnover intention which the employees in the organizations they are not linked ;earning with their intention to leave, we figure out in this study the job satisfaction positively influence organizational commitment this is refer for the employees will have the commitment for their organizations when they have job satisfaction first and organizational commitment has negative relationship with turnover intention, the studies shown that there are employees that could stay in the organization even of they do not have commitment for their organizations. Keywords: Organizational learning culture, job satisfaction, organizational commitment, turnover intention, privet sector and Saudi Arabia DOI: 10.7176/EJBM/13-8-17 Publication date: April 30th 202

Mining Genomes of Three Marine Sponge-Associated Actinobacterial Isolates for Secondary Metabolism

Here, we report the draft genome sequences of three actinobacterial isolates, Micromonospora sp. RV43, Rubrobacter sp. RV113, and Nocardiopsis sp. RV163 that had previously been isolated from Mediterranean sponges. The draft genomes were analyzed for the presence of gene clusters indicative of secondary metabolism using antiSMASH 3.0 and NapDos pipelines. Our findings demonstrated the chemical richness of sponge-associated actinomycetes and the efficacy of genome mining in exploring the genomic potential of sponge-derived actinomycetes