THERAPEUTIC BENEFITS OF TAKRA (BUTTERMILK) FOR HUMAN HEALTH

In Ayurveda it is considered that the basis of both the health and the diseases is Ahara (food). Ahara is considered as Prana (basis of life). Acharya Kashyap had clearly stated that Ahara is the best medicine. Takra (buttermilk) is one of the Aharadravya described in Ayurved with lots of medicinal properties. Use of Takra is indicated as single drug or Anupan (vehicle) or as Pathya (wholesome) in various diseases like Grahni (sprue), piles, diarrhea etc.. Presence of MFGM, sphingolipids, casiens, lactoferrins, various vitamins etc. has been detected in buttermilk. These constituents somewhat explain the mechanism of action of buttermilk. In Bhavprakash Nighantu, it is clearly stated that a person who consumes Takra never suffers from any disease and where Takra (buttermilk) is used as medicine for a disease then there is never relapse of that disease. Takra is easily palatable and can be used both for prevention and treatment of diseases

GO-MUTRA : BOON TO HUMAN BEINGS

Cow is considered as mother in Indian tradition. Go-mutra (cow urine) is one of the ingredient of Panchgawya, extensively used in Ayurved for treatment of many diseases. Go-mutra (cow urine) is used in treatment since time immemorial as cited in Atharvaveda, Carak Samhita, Sushrut Samhita, Vagbhatt, Bhavprakash etc. Go-mutra (cow urine) is a divine medicine considered as Medhya (intellect promoting) and is used for treatment of various diseases. Go-mutra (cow urine) as a single medicine is capable of curing diseases like Kandu (pruritis), Kilas (skin disorder), Shool (pain), Gulm, Atisar (diarrhea), Vaatrog, Kaas (cough), Kusth (skin disorders), Krimi (worm infestation), Pandu (anaemia) and Udarrog (abdominal distention). Go-mutra (cow urine) is extensively used in various Ayurvedic preparations like Go-mutra Haritaki, Sanjeevani Vati etc.Recent studies has proved efficacy of Go-mutra (cow urine) in diseases like diabetes, blood pressure, cancer etc. Various chemical substances like Aurum hydroxide etc. and vitamins present in cow urine explain its medicinal properties. Due to such vast utility of Go-mutra (cow urine), its synonym is Brahmambu & thus, it is considered as elixir of life by Acharays of Ayurveda. Go-mutra (cow urine) is the most effective natural remedy & safest method of treatment bestowed upon us by mother-nature. This paper will put forward the constituents of Go-mutra and its medicinal importance

RATIONALITY BEHIND AYURVEDA COMPOUND FORMULATIONS- A BIRDS EYE VIEW

Ayurveda is Indian heritage system of medicine gifted by ancient Acharya. It provides scientific approach for dealing human health issues with tools of nature like herbs, minerals, metals etc. It states that every substance in the universe can be applied as medicine with the help of Yukti or logical approach of physicians. In present era, whole world is looking towards Ayurveda for its novel natural healing modalities to get relief from their ailments whether physical or mental. Hence here is the need for development of more numbers of Ayurveda formulations to overcome the different health hazard. Moreover invention of more formulations for newly developed diseases like cancer, AIDs, dengue etc. is also needed. But these herbal preparations also face problems like adulteration, non-availability in a particular area or extinction of herbs due to excessive use of a particular herb. On this background present study was undertaken to analyse the fundamental rationality behind Ayurveda formulations mentioned in various ancient transcripts. Literary data regarding evolving a formulation was scrutinized with examples of important formulations mentioned in various texts. This study results out that for developing a particular formulation, factors like availability, palatability, potency, safety, efficacy etc. should be considered.

An inclusive approach to designing a multi-epitope chimeric vaccine for Taenia infections by integrating proteomics and reverse vaccinology

BackgroundSoil- and water-transmitted helminths are a major concern in the developing world due to their high prevalence. More than a quarter of the population were estimated to be infected with helminths in these endemic zones.Research designAn in silico approach was used to design a vaccine construct against the Taenia genus utilizing the proteomic information and evaluation of the construct using immune-informatics.ResultsOur study identified 451 conserved proteins in Taenia spp. using the existing proteome; out of these, 141 were found to be expressed in cysticerci. These proteins were screened for antigenic epitopes and a multi-subunit vaccine was constructed. The constructed vaccine was assessed for its efficacy in mounting the appropriate immune response. Our constructed vaccine showed stability and optimal performance against the TLR 4 receptor, which is reported to be upregulated in Taenia infections in hosts.ConclusionImmune-informatics tools help design vaccines for neglected diseases such as those attributed to helminths, which are known to cause widespread morbidity. Our vaccine construct holds tremendous potential in conferring protection against all Taenia spp. of clinical relevance to human

Heating and lighting: understanding overlooked energy-consumption activities in the Indian residential sector

Understanding the climate impact of residential emissions starts with determining the fuel consumption of various household activities. While cooking emissions have been widely studied, non-cooking energy-consumption activities in the residential sector such as heating and lighting, have been overlooked owing to the unavailability of data at national levels. The present study uses data from the Carbonaceous Aerosol Emissions, Source Apportionment and Climate Impacts (COALESCE) project, which consists of residential surveys over 6000 households across 49 districts of India, to understand the energy consumed by non-cooking residential activities. Regression models are developed to estimate information in non-surveyed districts using demographic, housing, and meteorological data as predictors. Energy demand is further quantified and distributed nationally at a 4 × 4 km resolution. Results show that the annual energy consumption from non-cooking activities is 1106 [201] PJ, which is equal to one-fourth of the cooking energy demand. Freely available biomass is widely used to heat water on traditional stoves, even in the warmer regions of western and southern India across all seasons. Space heating (51%) and water heating (42%) dominate non-cooking energy consumption. In comparison, nighttime heating for security personnel (5%), partly-residential personal heating by guards, dominant in urban centers and kerosene lighting (2%) utilize minimal energy. Biomass fuels account for over 90% of the non-cooking consumption, while charcoal and kerosene make up the rest. Half of the energy consumption occurs during winter months (DJF), while 10% of the consumption occurs during monsoon, when kerosene lighting is the highest. Firewood is the most heavily used fuel source in western India, charcoal in the northern hilly regions, agricultural residues and dung cake in the Indo-Gangetic plains, and kerosene in eastern India. The study shows that ∼20% of residential energy consumption is on account of biomass-based heating and kerosene lighting activities

Evaluation of the safety, immunogenicity and efficacy of a new live-attenuated lumpy skin disease vaccine in India

ABSTRACTLumpy skin disease (LSD) was reported for the first time in India in 2019 and since then, it has become endemic. Since a homologous (LSD-virus based) vaccine was not available in the country, goatpox virus (GPV)-based heterologous vaccine was authorized for mass immunization to induce protection against LSD in cattle. This study describes the evaluation of safety, immunogenicity and efficacy of a new live-attenuated LSD vaccine developed by using an Indian field strain, isolated in 2019 from cattle. The virus was attenuated by continuous passage (P = 50) in Vero cells. The vaccine (50th LSDV passage in Vero cells, named as Lumpi-ProVacInd) did not induce any local or systemic reaction upon its experimental inoculation in calves (n = 10). At day 30 post-vaccination (pv), the vaccinated animals were shown to develop antibody- and cell-mediated immune responses and exhibited complete protection upon virulent LSDV challenge. A minimum Neethling response (0.018% animals; 5 out of 26,940 animals) of the vaccine was observed in the field trials conducted in 26,940 animals. There was no significant reduction in the milk yield in lactating animals (n = 10108), besides there was no abortion or any other reproductive disorder in the pregnant animals (n = 2889). Sero-conversion was observed in 85.18% animals in the field by day 30 pv

Abstracts of International Conference on Innovations in Business Management

This book contains abstracts of the various research ideas of the academic community and practitioners of management presented at the International Conference on Innovations in Business Management (ICIBM 2020). The researchers have contributed toward various themes of the conference such as sustainable economy, supply chain, women-empowerment, export-import, microfinance, government policies, etc. We strongly believe that it will open up further scope for in-depth research in various disciplines of business management. Best wishes to the participants to have detailed discussions on the above-said wide range of areas. Conference Title: International Conference on Innovations in Business ManagementConference Acronym: ICIBM 2020Conference Date: 16-17 January 2020Conference Location: ICFAI University, Dehradun, IndiaConference Organizers: ICFAI Business School, ICFAI University, Dehradun, India & University of Derby, United Kingdo