18 research outputs found

    Globalization of Services in Practice. (Analysis of Success on Polish Example in the Years 2003-2011)

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    The globalised world is looking for savings and actually finds it in Poland. Global economy is a system of connected vessels, functioning in close relations, with increasing role of Poland. The text demonstrates the developmental perspectives of outsourcing and offshoring in the largest Polish metropolies and the possibilities of the development of smaller cities

    Guidelines from the Polish Surgical Society and Polish Society of Oncological Surgery Concerning Quality Assurance for Centres Performing Cytoreductive Procedures and HIPEC Procedures in the Treatment of Primary and Secondary Peritoneal Tumours

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    Surgical treatment of patients with peritoneal metastases in combination with Hyperthermic intraperitoneal Chemotherapy (HIPEC) and systemic treatments is applied with increasing frequency and, with correct patient qualification, allows for obtaining 5-year survival at a level of 32–52%. The conditions necessary for positive results of such treatment include the high experience of a given centre, its appropriate infrastructure, and appropriate patient qualification for the procedure. As a result of the debate connected with the need to evaluate treatment quality and results, at the request of the Peritoneal Cancer Section of the Polish Society of Oncological Surgery, the conditions for quality assurance were worked out and a Quality Assurance Commission was set up for the centres performing cytoreductive procedures and HIPEC procedures in the treatment of primary and secondary peritoneal tumours

    Polish consensus on gastric cancer diagnosis and treatment – update 2022

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    This document – “Polish consensus on gastric cancer diagnosis and treatment – update 2022” – represents an expert consensus following a year’s worth of dedicated effort by a team of specialists throughout 2021, put forward in a con­ference in December 2021 in Krakow, and finalized below for publication in 2022. The effective date of this document is June 14th 2022. The work that went into updating this consensus was made under auspices of the Polish Society of Surgical Oncology and the Association of Polish Surgeons

    "Stare" i "nowe" media w kontekście kampanii politycznych i sprawowania władzy

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    Praca recenzowana / peer-reviewed paperPublikacja składa się z piętnastu tekstów autorów reprezentujących ważne ośrodki akademickie kraju. Podzielona została na dwie części. Pierwszą stanowią teksty ukazujące wieloaspektowość funkcjonowania mediów w przestrzeni publicznej. Druga część publikacji to zróżnicowane przykłady zastosowania nowoczesnych mediów w funkcjonowaniu współczesnej polityki światowej i krajowej

    Polski konsensus diagnostyki i leczenia raka żołądka – aktualizacja 2022

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    This document – “Polish consensus on gastric cancer diagnosis and treatment – update 2022” – represents an expert consensus following a year’s worth of dedicated effort by a team of specialists throughout 2021, put forward in a con­ference in December 2021 in Krakow, and finalized below for publication in 2022. The effective date of this document is June 14th 2022. The work that went into updating this consensus was made under auspices of the Polish Society of Surgical Oncology and the Association of Polish Surgeons.Końcowy kształt niniejszego dokumentu – „Polski konsensus diagnostyki i leczenia raka żołądka – aktualizacja 2022” – jest wynikiem prac zespołu ekspertów, które prowadzone były w 2021 r., zwieńczone konferencją w grudniu 2021 r. w Krakowie i przygotowane w ostatecznej wersji do publikacji w roku 2022. Pracom nad aktualizacją konsensusu patronowały równorzędnie dwa towarzystwa naukowe: Polskie Towarzystwo Chirurgii Onkologicznej i Towarzystwo Chirurgów Polskich

    Liberal capitalism in crisis

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    Praca recenzowana / Peer-reviewed paperWychodząc więc z założenia, że konieczne jest stworzenie nowej społecznie pożądanej rzeczywistości oraz mając nadzieję, że państwa będą zdolne uwolnić się od liberalnych złudzeń, w niniejszej monografii przedstawiono nie tylko przyczyny, źródła i ekonomiczne skutki obecnego fundamentalnego kryzysu kapitalizmu, ale i współczesne systemy gospodarcze nieoparte na doktrynie liberalizmu rynkowego

    Gene expression alterations induced by low molecular weight heparin during bowel anastomosis healing in rats

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    Colon anastomosis is therapeutically challenging because multiple, usually undetectable factors influence a spectrum of repair mechanisms. We hypothesized that low molecular weight heparins, routinely administered perioperatively, may differentially affect gene expression related to colon healing. Twenty pairs of untreated and enoxaparin-treated rats underwent left-side hemicolectomy with a primary end-to-end anastomosis. Normal colon and anastomotic bowel segments were resected on day 0 and on days 1, 3, 5, and 7 after surgery, respectively. Serial anastomosis transverse cross-sections were evaluated microscopically and by microarray (Rat Genome 230 2.0, Affymetrix). Differentially expressed probe sets were annotated with Gene Ontology. We also examined the influence of enoxaparin on fibroblast proliferation and viability in vitro. Among the 5476 probe sets, we identified differential expression at each healing time point, yielding 79 subcategories. Most indicated genes were involved in wound healing, including multicellular organismal development, locomotory behavior, immune response, cell adhesion, inflammatory response, cell-cell signaling, blood vessel development, and tissue remodeling. Although we found no intensity differences in histological features of healing between enoxaparin-treated and control rats, treatment did induce significant expression changes during early healing. Of these changes, 83 probe sets exhibited at least twofold changes and represented different functional annotations, including inflammatory response, regulation of transcription, regulation of apoptosis, and angiogenesis. Fibroblast culture confirmed an anti-viability effect of enoxaparin. Enoxaparin affects colon wound-related gene expression profiles, but further studies will resolve whether heparin treatment is a risk factor after intestinal surgery, at least in some patients
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