The Mechanics of Intelligent Design — Good Enough to Teach?

Considerable debate has taken place in the last two years over whether or not Intelligent Design (ID) should be taught to high school students. This paper examines some of the basic features of ID as set out by its major proponents. It also outlines the arguments of detractors who would argue that ID is not science, but religion or creationism in disguise. These suggest that ID is a type of ‘god of the gaps’ argument which then languishes when mechanisms accounting for the appearance of complex objects or systems having the hallmarks of design are elucidated by further scientific research. It is also noted that while the complexity, functionality and apparent purpose of biological systems may have the appearance of being designed, other explanations exist. Further, it is noted that design theory is unable to speculate on the mechanism(s) leading to their formation. It is also observed that the design discussion has some general concepts which go beyond the specific ID framework and with which many more Christians in science resonate. Internationally, ID has not featured in school science curricula and attempts to integrate it into Australian school curricula should be very carefully evaluated with respect to the experiences of the global educational and scientific community

Intelligent Design: The Biochemical Challenge to Darwinian Evolution?

The idea that nature shows evidence of intelligent design has been argued by theologians and scientists for centuries. The most famous of the design arguments is Paley’s watchmaker illustration from his writings of the early 19th century. Interest in the concept of design in nature has recently had a resurgence and is often termed the Intelligent Design movement. Significant is the work of Michael Behe on biochemical systems. In his book, Darwin’s Black Box, Behe develops the idea that many biochemical systems are irreducibly complex in the sense that each component of these systems is essential for their functioning and cannot be removed or altered without compromising the system of which they are a part. Thus traditional Darwinian evolutionary theory has difficulty in explaining their development. When applied to the question of life’s origin on this planet, design arguments raise serious questions about traditional views of chemical evolution. To be considered a scientific alternative to Darwinian evolution, intelligent design needs to be empirically detectable. The development of a three-stage explanatory filter by William Dembski is arguably a fully scientific method that can, on the basis of observational data, reliably distinguish intelligent design in biological systems from undirected natural causes. However, at this stage, detection of intelligent design does not necessitate speculation on the nature of the designer, but does infer an intelligence behind the design

Automated precision alignment of optical components for hydroxide catalysis bonding

We describe an interferometric system that can measure the alignment and separation of a polished face of a optical component and an adjacent polished surface. Accuracies achieved are ∼ 1μrad for the relative angles in two orthogonal directions and ∼ 30μm in separation. We describe the use of this readout system to automate the process of hydroxide catalysis bonding of a fused-silica component to a fused-silica baseplate. The complete alignment and bonding sequence was typically achieved in a timescale of a few minutes, followed by an initial cure of 10 minutes. A series of bonds were performed using two fluids - a simple sodium hydroxide solution and a sodium hydroxide solution with some sodium silicate solution added. In each case we achieved final bonded component angular alignment within 10 μrad and position in the critical direction within 4 μm of the planned targets. The small movements of the component during the initial bonding and curing phases were monitored. The bonds made using the sodium silicate mixture achieved their final bonded alignment over a period of ∼ 15 hours. Bonds using the simple sodium hydroxide solution achieved their final alignment in a much shorter time of a few minutes. The automated system promises to speed the manufacture of precision-aligned assemblies using hydroxide catalysis bonding by more than an order of magnitude over the more manual approach used to build the optical interferometer at the heart of the recent ESA LISA Pathfinder technology demonstrator mission. This novel approach will be key to the time-efficient and low-risk manufacture of the complex optical systems needed for the forthcoming ESA spaceborne gravitational waves observatory mission, provisionally named LISA

Digestion of Repair Sites in Rat Liver DNA by Endogenous Nucleases

The proportion of sheared rat liver DNA recovered from benzoylated DEAE-cellulose in the final stage following stepwise elution with NaCl and caffeine solutions was dependent upon the DNA isolation procedure. An increase in the proportion of DNA containing single stranded regions, consequent upon delay or addition of Mg2+ prior to phenol extraction, suggested nuclease mediated degradation. Administration of methyl methanesulphonate to rats resulted in a consistent proportional increase in the caffeine-eluted fraction. The results of caffeine gradient elution of control and alkylated DNA from benzoylated DEAE-cellulose were consistent with repair-associated single stranded regions being substrates for endogenous single strand-specific exonucleases

Construction of rugged, ultrastable optical assemblies with optical component alignment at the few microradian level

A method for constructing quasimonolithic, precision-aligned optical assemblies is presented. Hydroxide-catalysis bonding is used, adapted to allow optimization of component fine alignment prior to the bond setting. We demonstrate the technique by bonding a fused silica mirror substrate to a fused silica baseplate. In-plane component placement at the submicrometer level is achieved, resulting in angular control of a reflected laser beam at the sub-10-μrad level. Within the context of the LISA Pathfinder mission, the technique has been demonstrated as suitable for use in space-flight applications. It is expected that there will also be applications in a wide range of areas where accuracy, stability, and strength of optical assemblies are important

The Biochemical and Pathophysiological Effects of Alcohol Consumption

While the stance of some conservative Christian (and other) groups advocating abstinence from alcohol intake may not be popular, contemporary research into alcohol and its effects on the body may lend weight to such a position. The consumption of alcohol, coupled with its addictive properties, can lead to a wide not only costly in medical terms but also in terms of domestic violence, accidents and antisocial behaviour. Alcohol is metabolised by the liver and this organ may be consequently damaged resulting in serious impairment of normal hepatic structure and function. Nearly all the physiological systems of the body are adversely affected by alcohol to varying degrees and the behavioural effects observed with intoxication are associated with compromised neurotransmitter functions in the brain and altered brain structure in the long term. Adverse consequences of alcohol intake may be evident in other systems including the cardiovascular, gastrointestinal, reproductive and immunological systems. There is an increased risk of atherosclerosis, cancers of the oral cavity, pancreatitis and immune system disturbances associated with prolonged alcohol intake. In pregnant women alcohol metabolism is reduced and as the developing foetus has lowered ability to metabolise blood alcohol compared to an adult there is an elevated risk of serious consequences associated with foetal alcohol syndrome. Despite the nearly overwhelming negative consequences of alcohol intake, the beneficial effects of drinking red wine linked to lowered heart disease despite a high fat diet (the ‘French Paradox’) may be associated with the antioxidants and other polyphenols also found in non-alcoholic red grape juice. Serious consideration of the effects of alcohol on the body should inform decisions on the intake of alcohol

The Effect of a Low-Fat, Plant-Based Lifestyle Intervention (CHIP) on Serum HDL Subfraction Levels - A Cohort Study

This conference abstract discusses a low-fat plant-based diet and the effect it has on HDL level

HDL Subfraction Changes with a Low-fat, Plant-based Complete Health Improvement Program (CHIP)

Background and Objectives: Low HDL concentrations are considered an important risk factor for cardiovascular disease. Interventions promoting a low-fat, plant-based eating pattern appear to reduce CVD risk while paradoxically also reducing HDL concentrations. Recent studies show HDL to comprise a range of subfractions, but the role these play in ameliorating the risk of CVD is unclear. The purpose of this study was to characterise changes in HDL subfractions in participants where HDL decreased following the CHIP intervention which promotes a low-fat, plant-based diet, with physical activity. Methods and Study Design: Individuals (n=22; mean age=55.4±16.3 years; 45.5% men, 54.5% women) participating in a CHIP intervention were assessed at baseline and 30 days for changes in BMI, blood pressure, lipid profile, (including large-, intermediate- and small-HDL subfractions) and fasting glucose. Results: HDL significantly decreased (10.6%, pConclusions: This paper discusses specific changes in HDL subfractions when overall-HDL decreases as a response to low fat, whole-food, plant-based eating and exercise. Additional research is required to elucidate the reasons through which behavioural therapies remodel the HDL particle and how this impacts the functional properties of HDL and CVD risk