16 research outputs found

    Telemedicine across the globe-position paper from the COVID-19 pandemic health system resilience PROGRAM (REPROGRAM) international consortium (Part 1)

    Get PDF
    Coronavirus disease 2019 (COVID-19) has accelerated the adoption of telemedicine globally. The current consortium critically examines the telemedicine frameworks, identifies gaps in its implementation and investigates the changes in telemedicine framework/s during COVID-19 across the globe. Streamlining of global public health preparedness framework that is interoperable and allow for collaboration and sharing of resources, in which telemedicine is an integral part of the public health response during outbreaks such as COVID-19, should be pursued. With adequate reinforcement, telemedicine has the potential to act as the “safety-net” of our public health response to an outbreak. Our focus on telemedicine must shift to the developing and under-developing nations, which carry a disproportionate burden of vulnerable communities who are at risk due to COVID-19

    HLA-DQA1*05 carriage associated with development of anti-drug antibodies to infliximab and adalimumab in patients with Crohn's Disease

    Get PDF
    Anti-tumor necrosis factor (anti-TNF) therapies are the most widely used biologic drugs for treating immune-mediated diseases, but repeated administration can induce the formation of anti-drug antibodies. The ability to identify patients at increased risk for development of anti-drug antibodies would facilitate selection of therapy and use of preventative strategies.This article is freely available via Open Access. Click on Publisher URL to access the full-text

    Analysis of Obstetric Fistula in Ethiopia

    No full text
    Objective: To study the association between social, demographic, cultural and maternal care practice variables and obstetric fistula status in Ethiopia. Materials and Methods: The most recent Ethiopia Demographic and Health Survey conducted in 2005 is used to study the association between social, demographic, cultural and maternal care practice and obstetric fistula. We use both univariate and bivariate analyses to describe the association between the selected variables on obstetric fistula status. Results: A number of social, demographic and maternal care practice variables are found to be significantly (p<0.05) associated with obstetric fistula status. These include level of education, age at first birth, place of residence, antenatal services and place of delivery. Conclusion: The study results emphasize the significance of both treatment and prevention activities in eradicating this highly preventable health condition of women in Ethiopia

    The Fast Food and Obesity Link: An Investigation of Consumption Patterns and Severity of Obesity in Pre-Bariatric Surgery Patients

    Get PDF
    We examined selected behavioral factors associated with severity of obesity among pre-operative bariatric surgery patients in the San Antonio area; focusing specifically on the effects of fast food consumption. We used ordered logistic regression to model the effects of behavioral and attitudinal variables on obesity outcomes. Our results indicated that among the behavioral factors, fast food consumption exerted the largest influence on higher levels of obesity. After controlling for several social and demographic characteristics, the effects of fast food consumption remained significant in the model. In fact, for each increase in fast food consumption there was a 26% increase in the odds of being super-morbidly obese versus the combined obese and morbidly obese designations, all else equal. This suggests that fast food plays a pivotal role in predicting severe obese outcomes

    Are some women more at risk of obstetric fistula in Uganda? Evidence from the Uganda demographic and health survey

    No full text
    With only four years left for the Millennium Development Goal’s 2015 deadline for reducing poor maternal health outcomes, developing countries are still bearing a huge burden of maternal morbidity worldwide. Estimates show that over 2 million women worldwide are suffering from obstetric fistula, the majority of which live in sub-Saharan Africa, Southeast Asia, and the Arab region. The purpose of this study is to shed a light on obstetric fistula by examining risk factors associated with this morbidity in Uganda. Descriptive and multivariate analyses were conducted using data from the 2006 Uganda Demographic and Health Survey. Older age at first sexual intercourse was significantly associated with a lower risk of obstetric fistula (OR=0.302) compared to younger age at first intercourse (7-14 years). Lack of autonomy was negatively associated with the risk of obstetric fistula; women who have problems securing permission from their husband to go seek care (OR=1.658) were more likely to suffer from this morbidity. Significant differentials in obstetric fistula have also been observed based on the region of residence: women living in Central (OR=4.923), East Central (OR=3.603), West Nile (OR=2.049), and Southwest (1.846) more likely to suffer from obstetric fistula than women living in North Central. Findings demonstrate the importance of improving geographical accessibility to maternal health care services, and emphasize the need to reinforce intervention programs, which seek to address gender inequalities

    Towards Improving Transparency of Count Data Regression Models for Health Impacts of Air Pollution

    No full text
    In studies on the health impacts of air pollution, regression analysis continues to advance far beyond classical linear regression, which many scientists may have become familiar with in an introductory statistics course. With each new level of complexity, regression analysis may become less transparent, even to the analyst working with the data. This may be especially true in count data regression models, where the response variable (typically given the symbol y) is count data (i.e., takes on values of 0, 1, 2, …). In such models, the normal distribution (the familiar bell-shaped curve) for the residuals (i.e., the differences between the observed values and the values predicted by the regression model) no longer applies. Unless care is taken to correctly specify just how those residuals are distributed, the tendency to accept untrue hypotheses may be greatly increased. The aim of this paper is to present a simple histogram of predicted and observed count values (POCH), which, while rarely found in the environmental literature but presented in authoritative statistical texts, can dramatically reduce the risk of accepting untrue hypotheses. POCH can also increase the transparency of count data regression models to analysts themselves and to the scientific community in general

    Perceived Social Norms About Oral PrEP Use: Differences Between African-American, Latino and White Gay, Bisexual and Other Men Who Have Sex with Men in Texas.

    No full text
    Correct and consistent condom use has been the primary method of HIV prevention until the FDA approve the use of PrEP in 2012. While strong evidence existing regarding the efficacy of PrEP, uptake has remained slower than anticipated. While work is underway to better understand the factors impacting uptake, the majority of this work as been focused on white gay, bisexual, and other men who have sex with men (GBMSM) living in metropolitan regions of the coastal U.S. The current study used a community-based framework to assess perceived social norms through a elicitation survey. A total of 104 GBMSM met inclusion criteria for the study. Several analytic categories emerged across questions and a number of differences were found across race and ethnicity such as who would approve or disapprove off PrEP and who would be likely to use PrEP. Further, we found differences between injunctive and descriptive norms. These findings suggest that there are unique factors contributing to PrEP uptake among racial and ethnic minority GBMSM and that to fully understand uptake a more robust measure of perceived norms may be needed
    corecore