28 research outputs found
Comparative analysis of anxiety assessment methods in athletes
Objective: to identify the most effective method for anxiety assessment in athletes. Materials and methods: the selective criteria were formulated and comparative analysis of 9 most commonly used methods of assessing the level of anxiety was made. 79 athletes of combat sports were tested (34 men, 45 women) in the preparative period of training with Lusher's color test and the integrative anxiety test by A.P. Bizyuk, L.I. Wasserman, B.V. Iovlev. Results: among nine methods most frequently mentioned in the literature, Lusher's color test with the calculation of diagnostic coefficients and the integrative anxiety test by A.P. Bizyuk, L.I. Wasserman, B.V. Iovlev were most consistent with the stated criteria. There were significant correlations between the calculated indices of Luscher's color test, which have physiological explanation: the correlation between the vegetative coefficient and the total deviation from the autogenic norm, mental working capacity, situational anxiety, and between total deviation from the autogenic norm and mental performance, sex (increase in the deviation from the autologous norm corresponds to a decrease in mental performance, an increase in the level of anxiety, parasympathetic tone, and need for rest and energy accumulation). The athletes have the low level of situational anxiety and an average level of personal anxiety if compared with average population values. Conclusions: the findings complement the results of other researchers who also confirmed the validity of use of color test and integrative anxiety test in professional sports to identify the threatening breakdown of mental adaptation and psycho-correction work among athletes
Forecasting morbidity with temporary disability of nurses in the regoional hospital according to their medical and social risk factors
Morbidity with temporary disability (MTD) of nurses in the Regional Hospital is analyzed in the Medical and biological article reference of this contingent is introduced here. The most significant medical and social risk factors are determined and forecasting models valuing health and morbidity among MTD nurses according to the cases and the amount of calendar days are worked out. The results of verification of the worked out models are open in the article.Π¦Π΅Π»Ρ ΡΠ°Π±ΠΎΡΡ - ΠΏΡΠΎΠ°Π½Π°Π»ΠΈΠ·ΠΈΡΠΎΠ²Π°ΡΡ Π·Π°Π±ΠΎΠ»Π΅Π²Π°Π΅ΠΌΠΎΡΡΡ Ρ Π²ΡΠ΅ΠΌΠ΅Π½Π½ΠΎΠΉ ΡΡΡΠ°ΡΠΎΠΉ ΡΡΡΠ΄ΠΎΡΠΏΠΎΡΠΎΠ±Π½ΠΎΡΡΠΈ (ΠΠΠ£Π’) ΠΌΠ΅Π΄ΠΈΡΠΈΠ½ΡΠΊΠΈΡ
ΡΠ΅ΡΡΠ΅Ρ ΠΎΠ±Π»Π°ΡΡΠ½ΠΎΠΉ ΠΊΠ»ΠΈΠ½ΠΈΡΠ΅ΡΠΊΠΎΠΉ Π±ΠΎΠ»ΡΠ½ΠΈΡΡ. ΠΡΠ΅Π΄ΡΡΠ°Π²Π»Π΅Π½Π° ΠΌΠ΅Π΄ΠΈΠΊΠΎ-Π±ΠΈΠΎΠ»ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠ°Ρ Ρ
Π°ΡΠ°ΠΊΡΠ΅ΡΠΈΡΡΠΈΠΊΠ° Π΄Π°Π½Π½ΠΎΠ³ΠΎ ΠΊΠΎΠ½ΡΠΈΠ½Π³Π΅Π½ΡΠ°. ΠΠΏΡΠ΅Π΄Π΅Π»Π΅Π½Ρ Π½Π°ΠΈΠ±ΠΎΠ»Π΅Π΅ Π·Π½Π°ΡΠΈΠΌΡΠ΅ ΠΌΠ΅Π΄ΠΈΠΊΠΎ-ΡΠΎΡΠΈΠ°Π»ΡΠ½ΡΠ΅ ΡΠ°ΠΊΡΠΎΡΡ ΡΠΈΡΠΊΠ° ΠΈ Π½Π° ΠΈΡ
ΠΎΡΠ½ΠΎΠ²Π΅ ΡΠ°Π·ΡΠ°Π±ΠΎΡΠ°Π½Ρ ΠΏΡΠΎΠ³Π½ΠΎΡΡΠΈΡΠ΅ΡΠΊΠΈΠ΅ ΠΌΠΎΠ΄Π΅Π»ΠΈ ΠΎΡΠ΅Π½ΠΊΠΈ ΡΠΎΡΡΠΎΡΠ½ΠΈΡ Π·Π΄ΠΎΡΠΎΠ²ΡΡ ΠΈ Π·Π°Π±ΠΎΠ»Π΅Π²Π°Π΅ΠΌΠΎΡΡΠΈ Ρ ΠΠ£Π’ ΠΌΠ΅Π΄ΠΈΡΠΈΠ½ΡΠΊΠΈΡ
ΡΠ΅ΡΡΠ΅Ρ ΠΏΠΎ ΡΠΈΡΠ»Ρ ΡΠ»ΡΡΠ°Π΅Π² ΠΈ ΡΠΈΡΠ»Ρ ΠΊΠ°Π»Π΅Π½Π΄Π°ΡΠ½ΡΡ
Π΄Π½Π΅ΠΉ. ΠΡΠΈΠ²Π΅Π΄Π΅Π½Ρ ΡΠ΅Π·ΡΠ»ΡΡΠ°ΡΡ Π²Π΅ΡΠΈΡΠΈΠΊΠ°ΡΠΈΠΈ ΡΠ°Π·ΡΠ°Π±ΠΎΡΠ°Π½Π½ΡΡ
ΠΌΠΎΠ΄Π΅Π»Π΅ΠΉ
The study of the structure of anxiety in athletes
Objective: to study the structure of disorders caused by anxiety in athletes. Materials and methods: the objects of the first task of the research were different terminological definitions and classifications of anxiety disorders. Comparative analysis of the definitions and concepts used in psychology, physiology, sports medicine, theory and methodology of physical education has been carried out. The second task was to determine the leading factors characterizing the psychological status of athletes, and to give them the descriptive characteristics. A factor analysis was conducted on the results of testing 79 athletes of combat sports (34 men, 45 women) using the M Luscher color test and the integrative anxiety test by AP Bizyuk, LI Wasserman, BV Iovlev. Results: Luscher's test scores (total deviation from the autogenous rate, mental performance, vegetative coefficient) explained only 14.5% of the total variance. Simultaneously, the indicator of situational anxiety from Luscher's test was not included in any factor. The informativeness of more detailed integrative anxiety test was significantly higher: its indicators were included in 3 factors, explaining totally 49.5% of the total variance, as well as in the general factor, which explains 33% of the total variance. Conclusions: the emotional component (emotions which cause situational anxiety) contributes largely to the total anxiety level, some smaller contribution accounts for the social components (fear of condemnation, dependence on the opinions of others), finally, the personal anxiety contributes to it even less
Durvalumab, with or without tremelimumab, plus platinum-etoposide in first-line treatment of extensive-stage small-cell lung cancer: 3-year overall survival update from CASPIAN
Background: In the phase III CASPIAN study, first-line durvalumab in combination with etoposide plus either cisplatin or
carboplatin (EP) significantly improved overall survival (OS) versus EP alone in extensive-stage small-cell lung cancer
(ES-SCLC). Durvalumab plus tremelimumab plus EP numerically improved OS versus EP, but did not reach statistical
significance. Here we report updated OS in censored patients after median follow-up of >3 years.
Patients and methods: 805 patients with treatment-naΓ―ve ES-SCLC were randomized 1 : 1 : 1 to durvalumab plus
EP, durvalumab plus tremelimumab plus EP, or EP. The two primary endpoints were OS for durvalumab plus EP
versus EP and for durvalumab plus tremelimumab plus EP versus EP.
Results: As of 22 March 2021 (median follow-up 39.4 months, 86% maturity), durvalumab plus EP continued to
demonstrate improved OS versus EP: hazard ratio (HR) 0.71 [95% confidence interval (CI) 0.60-0.86; nominal
P ΒΌ 0.0003]; median OS was 12.9 versus 10.5 months, and 36-month OS rate was 17.6% versus 5.8%. Durvalumab
plus tremelimumab plus EP continued to numerically improve OS versus EP: HR 0.81 (95% CI: 0.67-0.97; nominal
P ΒΌ 0.0200); median OS was 10.4 months, and 36-month OS rate was 15.3%. Twenty-seven and nineteen patients
in the durvalumab plus EP and durvalumab plus tremelimumab plus EP arms, respectively, remained on durvalumab
treatment at data cut-off.
Conclusions: Three times more patients were estimated to be alive at 3 years when treated with durvalumab plus EP
versus EP, with the majority still receiving durvalumab at data cut-off, further establishing durvalumab plus EP as
first-line standard of care for ES-SCLC
Prognostication of Recovery from Acute Stroke (PRAS Dataset)
The file titled "Stroke_ICH_Data" contains a table which is labeled the PRAS dataset after the project title βPrognostication of Recovery from Acute Strokeβ (6,7). The table holds records for 2016-2019 years from the stroke registry of Al Ain Hospital which serves as a tertiary level of care clinic. The dataset consists of de-identified patients data and weather parameters. We retrieved information on the following clinicodemographic risk factors of hemorrhagic stroke from medical histories: age, sex, body mass index, smoking status, history of cardiovascular diseases, and ethnicity. From the website National Oceanic and Atmospheric Administration for Al Ain city we requested the weather parameters for seven days before the stroke onset.THIS DATASET IS ARCHIVED AT DANS/EASY, BUT NOT ACCESSIBLE HERE. TO VIEW A LIST OF FILES AND ACCESS THE FILES IN THIS DATASET CLICK ON THE DOI-LINK ABOV
Prognostication of Recovery from Acute Stroke: R and Python Codes.
1. The file titled "ich_plots_dlnm.Rmd" contains the code in R for calculating Spearman and Pearson's correlation coefficients as well as designing distributed lag non-linear models (DLNMs). 2. ich_prediction_nn notebook contains data analysis, feature importance estimation and prediction on stroke severity and outcomes (NHSS and MRS scores). Different models were used for prediction (namely, logistic regression, random forest, extra treees, ADAboost, SVC, and dense neural network).THIS DATASET IS ARCHIVED AT DANS/EASY, BUT NOT ACCESSIBLE HERE. TO VIEW A LIST OF FILES AND ACCESS THE FILES IN THIS DATASET CLICK ON THE DOI-LINK ABOV
Structural aspects of an aluminium-based composite material strengthened with SiC particles
Translated from Russian (Report of the E.O. Paton Electric Welding Inst., Kiev, 1996)Available from British Library Document Supply Centre-DSC:9023.190(VR-Trans--9050)T / BLDSC - British Library Document Supply CentreSIGLEGBUnited Kingdo
NUTRITIONAL AND ENTERIC INEFFICIENCY AT COMPLICATED TRAUMA OF CERVICAL REGION OF VERTEBRAL COLUMN
The aim of research was the analysis of nutritional and enteric inefficiency at complicated trauma of cervical region of vertebral column. Material and Methods. The retrospective observational investigation has been carried out. Medical records of 29 patients with complicated trauma of cervical region of vertebral column for 2017-2016 years have been analyzed. Results. Disorder of motor-evacuation function of digestive tract was revealed in 37 % of cases on the first day after accident. Maximal intensity of enteroparesis and minimal level of total protein were registered on 7-10 days. The albumin level has been progressively decreased till 15 days. The erosion of gastric and duodenum mucosa was revealed by esophagogastroduodenoscopy in 50 % of patients on the first day. The basal metabolism value detected by indirect calorimetry was 30-50 % higher than value calculated by formula
Reappraisal of the Concept of Accelerated Aging in Neurodegeneration and Beyond
Background: Genetic and epigenetic changes, oxidative stress and inflammation influence the rate of aging, which diseases, lifestyle and environmental factors can further accelerate. In accelerated aging (AA), the biological age exceeds the chronological age. Objective: The objective of this study is to reappraise the AA concept critically, considering its weaknesses and limitations. Methods: We reviewed more than 300 recent articles dealing with the physiology of brain aging and neurodegeneration pathophysiology. Results: (1) Application of the AA concept to individual organs outside the brain is challenging as organs of different systems age at different rates. (2) There is a need to consider the deceleration of aging due to the potential use of the individual structureβfunctional reserves. The latter can be restored by pharmacological and/or cognitive therapy, environment, etc. (3) The AA concept lacks both standardised terminology and methodology. (4) Changes in specific molecular biomarkers (MBM) reflect aging-related processes; however, numerous MBM candidates should be validated to consolidate the AA theory. (5) The exact nature of many potential causal factors, biological outcomes and interactions between the former and the latter remain largely unclear. Conclusions: Although AA is commonly recognised as a perspective theory, it still suffers from a number of gaps and limitations that assume the necessity for an updated AA concept