Risk behaviors in youth from Mexico City: a retrospective study

In the transition from adolescence to adulthood, an increase in several risk behaviors endangers the well-being of future life. It is in this period when there are changes in the relationships of adolescents with their family environment; therefore, retrospective studies are valuable to understand how these changes occur. This research describes the changes in risk behaviors associated with sexual activity and the consumption of tobacco, alcohol and illegal drugs, from youth to adulthood. A sample of 5780 students, men and women, from Mexico City was used. The selection of participants was retrospective and they were evaluated in three stages during years (2003, 2006 and 2010) in a period of seven years. Eleven indicators of and Automated Medical Examination (EMA) were used to evaluate the four risk behaviors. The results showed significant relationships (p <0.001) between the risk behaviors and the gender of the students, also indicated that men had a greater number of risk behaviors than women. Likewise, significant differences were found in the risk behaviors (p <0.001) over time. The findings allowed us to observe an increase in risk behaviors in the transition from adolescence to adulthood, both in men and women

Evaluación de las condiciones acústicas en un Centro de Día relacionadas con un modelo gerontológico y el cuidado centrado en las personas mayores con demencia

9 páginas.Los factores ambientales afectan los niveles de ruido y el ruido aceptable entre las personas es subjetivo en diferentes contextos. El cuidado de la salud en personas mayores con demencia requiere de un medio físico-espacial de apoyo con características auditivas específicas, por ello el control acústico debe ser regulado. El objetivo de este estudio fue evaluar el diseño acústico de un centro de día para establecer si el modelo de atención centrada en la persona satisfacía el confort acústico en las personas mayores con demencia. La metodología consistió en determinar tiempo de reverberación de un espacio utilizado para la estimulación cognitiva, posteriormente se definió una propuesta de remodelación en materia de diseño, además de considerar sistemas constructivos que favorecieran el acondicionamiento acústico. Los resultados indicaron que para el aislamiento fue importante integrar muros masivos y flexibles, así como plafones acústicos. Nótese que este acondicionamiento dependió en gran medida de la función y diseño del espacio arquitectónico, el cual se basó en el modelo gerontológico. Las recomendaciones de diseño acústico se pueden aplicar para mejorar el modelo de atención centrada en la persona.Coordinación de Posgrado de Ciencias y Artes para el Diseñ

Accuracy of transrectal ultrasonography for evaluation of corpora lutea in hair sheep

Current study assessed the reliability of transrectal ultrasonography (US; Aloka SSD 500) for assessment of presence and size of corpus luteum (CL), evaluated by non-skilled operator in ovaries (n = 58) from 29 hair sheep and compared with subsequent macroscopic (or postmortem; PM) evaluation. The sensitivity, specificity and positive and negative predictive value of the US technique to detect presence of luteal tissue in an ovary were 83.3, 97.1, 95.2 and 89.2%, respectively; and to determine the number of CL in ovaries (n = 21) with single ovulation were 85.7, 97.1, 94.7 and 89.2%, respectively. Sensitivity, dropped to 33.3%, in ovaries (n = 3) bearing more than one CL. There were not significant differences between mean diameters of CL, measured by US and PM. The number of CL with differences between US and PM measures, the range of error, varying between 0-20%, &gt;20- 30% and &gt;30%, were 14 (77%), 2 (6%) and 4 (17%), respectively. These results indicate that US technique is an effective tool for determining both presence and size of luteal tissue in hair sheep with unknown stage of the reproductive cycle

Values, preferences and burden of treatment for the initiation of GLP-1 receptor agonists and SGLT-2 inhibitors in adult patients with type 2 diabetes: a systematic review

Objectives Assess values, preferences and burden of treatment that patients with type 2 diabetes consider when initiating glucagon-like peptide-1 receptor agonists (GLP-1 RA) or sodium-glucose cotransporter-2 inhibitors (SGLT-2i) compared with other glucose-lowering options.Methods Paired reviewers independently included studies reporting quantitative or qualitative methods to assess values, preferences and burden of treatment reported by patients with type 2 diabetes regarding the initiation of GLP-1 RA or SGLT-2i over other alternatives. A systematic search in MEDLINE, Scopus, EMBASE, Web of Science and Cochrane Central Register of Controlled Trials from inception until May 2020 was performed by an experienced librarian. Risk of bias was assessed with a specifically designed tool for values and preferences studies.Results 17 studies (7296 patients) proved eligible. Studies fulfilling criteria for SGLT-2i were not identified. Five studies (2662 patients) evaluated preferences for GLP-1 RA compared with other glucose-lowering medications. 12 studies (4634 patients) evaluated preferences between, at least, two kinds of GLP-1 RA or their injection devices based on the following attributes: efficacy, dose, application frequency, device characteristics. Among studies comparing GLP-1 RA to other glucose-lowering medications, some preferences were observed for dypeptil peptidase-4 inhibitors compared with once daily liraglutide. Comparing different attributes of GLP-1 RA drugs and devices, cardiovascular risk reduction, glucose lowering potential, once weekly and simple administered regimens were the most preferred.Conclusions As no evidence for preferences on SGLT-2i was available, only preferences for GLP-1 RA were assessed; however, evidence is still limited for the latter. Studies comparing preferences for GLP1-RA to other glucose-lowering alternatives only included twice daily or once daily injection regimens of GLP-1 RA drugs. According to our findings, once weekly alternatives are widely preferred than the formers. The extent to which patients with type 2 diabetes value reduced adverse cardiovascular and kidney outcomes, weighed benefits against harms and burden of treatment is limited and with very low certainty

Socioeconomic Inequalities and Toothbrushing Frequency among Schoolchildren Aged 6 to 12 Years in a Multi-Site Study of Mexican Cities: A Cross-Sectional Study

Periodic toothbrushing is the most common, effective, and reliable way to mechanically remove biofilm from oral tissues. The objective of the present study was to determine the association between toothbrushing frequency and socioeconomic position for schoolchildren between 6 and 12 years of age in four cities in Mexico. A cross-sectional study was conducted on 500 Mexican schoolchildren between 6 and 12 years of age from public schools in four Mexican cities. Questionnaires were administered to the parents/guardians of the schoolchildren to obtain the variables included in the study. The dependent variable was toothbrushing frequency, dichotomized as: 0 = less than twice a day and 1 = at least twice a day. The analysis was performed in Stata. The average age of the schoolchildren was 8.9 1.9 years; 50.4% were female. The prevalence of toothbrushing was 52.8% (at least twice a day) (95% CI = 48.457.1). In the multivariate model, the variables associated (p < 0.05) with toothbrushing frequency were older age of the schoolchild (OR = 1.14); younger age of the mother (OR = 0.93); being a girl (OR = 1.70); being enrolled in Seguro Popular (OR = 0.69); being in a household that was owned (OR = 2.43); and being a schoolchild who lived in a home that owned a car (OR = 1.31). The prevalence of toothbrushing at least twice a day was just over 50% in these Mexican children. We found demographic and socioeconomic variables to be associated with toothbrushing. Based on socioeconomic variables that were associated with toothbrushing frequency—such as health insurance, home ownership and the household owning a car—the results of the present study confirm the existence of health inequalities in toothbrushing frequency

Síntesis de los fotocatalizadores binarios SnO2/TiO2y ternarios SnO2/TiO2/nanohojas de g-C3N4 para la degradación de naranja de metilo y ciprofloxacino en presencia de luz ultravioleta

When emergent pollutantsare in wastewater they need oxidation advanced processes for their degradation, such Heterogeneous Photocatalysis. Nowadays more efficient photocatalysts than titanium dioxide (TiO2) are being sought to degrade complex molecules. Nanoparticles and Quantum Dots (QDs) of Tin Oxide (SnO2) were synthesized by different methods, binary SnO2/TiO2and ternary SnO2/TiO2/g-C3N4nanosheets heterojunctions were synthetized by wet impregnation method to Methyl Orange (MO) as model pollutant and Ciprofloxacin (CIP) degradation. The most efficient photocatalysts for MO degradation were SnO2-SG300/P25 andP25. The SnO2-QDs/P25 junction showed a great MO adsorption capacity. The binary heterojunctions SnO2-npAldrich/P25 and SnO2-SG300/P25 showed higher degradation percentages than TiO2and P25.Los contaminantes emergentes,al encontrarse en aguas residuales, requieren procesos avanzados de oxidación para su degradación, como la fotocatálisis heterogénea. Actualmente se buscan fotocatalizadores más eficientes que el dióxido de titanio (TiO2) para degradar moléculas complejas. Se sintetizó dióxido de estaño (SnO2) nanométrico y puntos cuánticos (QDs) por distintos métodos;se sintetizaron juntas binarias de SnO2/TiO2y juntas ternarias de SnO2/TiO2/nanohojas de g-C3N4por impregnación húmeda, para la degradación de Naranja de Metilo (NM) como contaminante modelo y Ciprofloxacino (CIP). Los fotocatalizadores más eficientes para la degradación de NM fueron SnO2-SG300/P25 y P25. La junta SnO2-QDs/P25 mostró una gran capacidad de adsorción del NM. Para la degradación de CIP las juntas SnO2-npA/P25 y SnO2-SG300/P25 mostraron porcentajes de degradación superiores al TiO2y P2

-NC-ND 4.0

Abstract The geographic distribution of Ophioblenna antillensis Lütken, 1859 is extended inside the Gulf of Mexico. This species is otherwise known in the Caribbean region as the &quot;slimy snake of the Antilles&quot;, and is recognizable by soft skin covering the entire body, arms 5 times the disc diameter with big dorsal arm plates, and 7 completely naked, pointed and thin arm spines. All Rights Reserve

miniBELEN: a modular neutron counter for (a, n) reactions

miniBELEN is a modular and transportable neutron moderated counter with a nearly flat neutron detection efficiency up to 10 MeV. Modularity implies that the moderator can be reassembled in different ways in order to obtain different types of response. The detector has been developed in the context of the Measurement of Alpha Neutron Yields (MANY) collaboration, which is a scientific effort aiming to carry out measurements of (a, n) production yields, reaction cross-sections and neutron energy spectra. In this work we present and discuss several configurations of the miniBELEN detector. The experimental validation of the efficiency calculations using 252Cf sources and the measurement of the 27Al(a, n) 30P reaction is also presented.This work has been supported by the Spanish Ministerio de Economía y Competitividad under grants FPA2017-83946- C2-1 & C2-2 and PID2019-104714GB-C21 & C22, the Generalitat Valenciana Grant PROMETEO/2019/007, both cofounded by FEDER (EU), and the SANDA project funded under H2020-EURATOM-1.1 Grant No. 847552. The authors acknowledge the support from Centro de Microanálisis de Materiales (CMAM) - Universidad Autónoma de Madrid, for the beam time proposal (Comissioning of neutron detector systems for (a,݊n) reaction measurements) with code P01156, and its technical staff for their contribution to the operation of the accelerator.Article signat per 41 autors/es: N. Mont-Geli, A. Tarifeño-Saldivia, L.M. Fraile, S. Viñals, A. Perea, M. Pallàs, G. Cortés, E. Nácher, J.L. Tain, V. Alcayne, A. Algora, J. Balibrea-Correa, J. Benito, M.J.G. Borge, J.A. Briz, F. Calviño, D. Cano-Ott, A. De Blas, C. Domingo-Pardo, B. Fernández, R. Garcia, G. García, J. Gómez-Camacho, E.M. González-Romero, C. Guerrero, J. Lerendegui-Marco, M. Llanos, T. Martínez, E. Mendoza, J.R. Murias, S.E.A. Orrigo, A. Pérez de Rada, V. Pesudo, J. Plaza, J.M. Quesada, A. Sánchez, V. Sánchez-Tembleque, R. Santorelli, O. Tengblad, J.M. Udías and D. Villamarín.Postprint (published version

Mujeres que inspiran…Grandes historias de guerreras

Recopilación de historias propias o contadas por terceros de mujeres que han superado retos, dificultades, competencias y cómo han conseguido lograr hazañas inspiradoras.Collection of own or told stories by third parties of women who have overcome challenges, difficulties, competencies and how they have managed to achieve inspiring feats.Yamel Rodríguez -- Iber James Quiñones -- Diana Yamileth Velasquez Maldonado -- Nidia Karina Mora Londoño -- Aura María Rosero -- Catherine Caicedo -- David Alejandro Mera Benavides -- Elizabeth Cárdenas Berrío -- Jhon Jairo Leal F. -- Miguel Ángel Solís -- Milton Cesar Mera Osorio -- Elizabeth González Londoño -- Lorena Villegas -- Ana María Cortés Rosero -- Jhonathan Paul Obando Vera -- María Elena Realpe Delgado -- Carolina Medina Alcalde -- Yaneth Ariasna34 página

Phage-Derived and Aberrant HaloTag Peptides Immobilized on Magnetic Microbeads for Amperometric Biosensing of Serum Autoantibodies and Alzheimer's Disease Diagnosis

An electrochemical biosensing platform for serum autoantibodies (AAbs) detection is reported in this work, exploiting for the first time six Alzheimer's disease (AD)-specific phage-derived and frameshift aberrant HaloTag peptides as receptors, immobilized on magnetic microbeads (MBs) surface and captured on disposable electrodes to perform amperometric detection. Operational analytical characteristics and clinical diagnostic ability of the bioplatform were probed in optimized key experimental conditions by analysing serum AAbs of AD patients and healthy subjects. The value of 100% obtained for AUC, sensitivity, and selectivity from the all peptides combined ROC curve, indicate full AD-diagnostic capability of the methodology, which was further implemented, as proof of concept, in a POC multiplexing platform to detect the signature in a single test over clinically actionable times (1 h 15 min), opening great promise for the type of diagnosis and AD patients’ monitoring follow-up currently pursued