3,425 research outputs found
Amorphous Systems in Athermal, Quasistatic Shear
We present results on a series of 2D atomistic computer simulations of
amorphous systems subjected to simple shear in the athermal, quasistatic limit.
The athermal quasistatic trajectories are shown to separate into smooth,
reversible elastic branches which are intermittently broken by discrete
catastrophic plastic events. The onset of a typical plastic event is studied
with precision, and it is shown that the mode of the system which is
responsible for the loss of stability has structure in real space which is
consistent with a quadrupolar source acting on an elastic matrix. The plastic
events themselves are shown to be composed of localized shear transformations
which organize into lines of slip which span the length of the simulation cell,
and a mechanism for the organization is discussed. Although within a single
event there are strong spatial correlations in the deformation, we find little
correlation from one event to the next, and these transient lines of slip are
not to be confounded with the persistent regions of localized shear --
so-called "shear bands" -- found in related studies. The slip lines gives rise
to particular scalings with system length of various measures of event size.
Strikingly, data obtained using three differing interaction potentials can be
brought into quantitative agreement after a simple rescaling, emphasizing the
insensitivity of the emergent plastic behavior in these disordered systems to
the precise details of the underlying interactions. The results should be
relevant to understanding plastic deformation in systems such as metallic
glasses well below their glass temperature, soft glassy systems (such as dense
emulsions), or compressed granular materials.Comment: 21 pages, 18 figure
The Group of 20 transnational policy community: governance networks, policy analysis and think tanks
Civil society and financial markets : what is not happening and why
Why have commercial financial flows â as a major force in contemporary society with a number of significant problematic consequences â attracted relatively little effective public-interest response from civil society? Change-oriented NGOs, labour unions, faith-based organisations and other social movements have mostly remained in the shadows vis-Ă -vis private financial markets. Impacts from these citizen associations have not gone beyond promoting modest rises in public awareness, certain limited policy shifts, and minor institutional reforms of a few public governance agencies. The reasons for these scant achievements are partly related to capacities and practices in civil society groups, relevant governance agencies, and financial firms. Also important in constraining civil society impacts to reform and transform contemporary financial markets are deeper structural circumstances such as embedded social hierarchies (among countries, classes, etc.), the pivotal role of finance capital in accumulation processes today, and the entrenchment of prevailing neoliberal policy discourses
Patenting and licensing of university research: promoting innovation or undermining academic values?
Since the 1980s in the US and the 1990s in Europe, patenting and licensing activities by universities have massively increased. This is strongly encouraged by governments throughout the Western world. Many regard academic patenting as essential to achieve 'knowledge transfer' from academia to industry. This trend has far-reaching consequences for access to the fruits of academic research and so the question arises whether the current policies are indeed promoting innovation or whether they are instead a symptom of a pro-intellectual property (IP) culture which is blind to adverse effects. Addressing this question requires both empirical analysis (how real is the link between academic patenting and licensing and 'development' of academic research by industry?) and normative assessment (which justifications are given for the current policies and to what extent do they threaten important academic values?). After illustrating the major rise of academic patenting and licensing in the US and Europe and commenting on the increasing trend of 'upstream' patenting and the focus on exclusive as opposed to non-exclusive licences, this paper will discuss five negative effects of these trends. Subsequently, the question as to why policymakers seem to ignore these adverse effects will be addressed. Finally, a number of proposals for improving university policies will be made
Driving calmodulin protein towards conformational shift by changing ionization states of select residues
Proteins are complex systems made up of many conformational sub-states which are mainly determined by the folded structure. External factors such as solvent type, temperature, pH and ionic strength play a very important role in the conformations sampled by proteins. Here we study the conformational multiplicity of calmodulin (CaM) which is a protein that plays an important role in calcium signaling pathways in the eukaryotic cells. CaM can bind to a variety of other proteins or small organic compounds, and mediates different physiological processes by activating various enzymes. Binding of calcium ions and proteins or small organic molecules to CaM induces large conformational changes that are distinct to each interacting partner. In particular, we discuss the effect of pH variation on the conformations of CaM. By using the pKa values of the charged residues as a basis to assign protonation states, the conformational changes induced in CaM by reducing the pH are studied by molecular dynamics simulations. Our current view suggests that at high pH, barrier crossing to the compact form is prevented by repulsive electrostatic interactions between the two lobes. At reduced pH, not only is barrier crossing facilitated by protonation of residues, but also conformations which are on average more compact are attained. The latter are in accordance with the fluorescence resonance energy transfer experiment results of other workers. The key events leading to the conformational change from the open to the compact conformation are (i) formation of a salt bridge between the N-lobe and the linker, stabilizing their relative motions, (ii) bending of the C-lobe towards the N-lobe, leading to a lowering of the interaction energy between the two-lobes, (iii) formation of a hydrophobic patch between the two lobes, further stabilizing the bent conformation by reducing the entropic cost of the compact form, (iv) sharing of a Ca+2 ion between the two lobes
The impact of marketisation on postgraduate career preparedness in a high skills economy
This study focuses on the consequences for high skills development of the erosion of the once clear demarcation between higher education and business. It contributes to the broader debate about the relevance of higher education for thewell-being of the society of the future. The research explores the effects of marketisation on the postgraduate curriculum and studentsâ preparedness for careers in public relations and marketing communications. Interviews with lecturers and students in two universities in the UK and Australia indicate that a tension exists between academic rigour and corporate relevancy. The consequences are a diminution of academic attachment to critique and wider social/cultural engagement, with a resulting impoverishment of studentsâ creative abilities and critical consciences. Subsequently, graduates of public relations and marketing communications, and to some extent those from other profession-related disciplines, are insufficiently prepared for careers as knowledge workers in a future high-skills economy
Transforming teacher education, an activity theory analysis
This paper explores the work of teacher education in England and Scotland. It seeks to locate this work within conflicting socio-cultural views of professional practice and academic work. Drawing on an activity theory framework that integrates the analysis of these contradictory discourses with a study of teacher educatorsâ practical activities, including the material artefacts that mediate the work, the paper offers a critical perspective on the social organisation of university-based teacher education. Informed by Engeströmâs activity theory concept of transformation, the paper extends the discussion of contradictions in teacher education to consider the wider socio-cultural relations of the work. The findings raise important questions about the way in which teacher education work within universities is organised and the division of labour between schools and universities
Mass dependence of light nucleus production in ultrarelativistic heavy ion collisions
Light nuclei can be produced in the central reaction zone via coalescence in
relativistic heavy ion collisions. E864 at BNL has measured the production of
ten light nuclei with nuclear number of A=1 to A=7 at rapidity and
. Data were taken with a Au beam of momentum of 11.5 A
on a Pb or Pt target with different experimental settings. The
invariant yields show a striking exponential dependence on nuclear number with
a penalty factor of about 50 per additional nucleon. Detailed analysis reveals
that the production may depend on the spin factor of the nucleus and the
nuclear binding energy as well.Comment: (6 pages, 3 figures), some changes on text, references and figures'
lettering. To be published in PRL (13Dec1999
Influences on academics' approaches to development: voices from below
The purpose of this qualitative case study research was to explore faculty-based academicsâ views on what influences their behaviours and attitudes towards their development. Informed by critical realist ontology, the data collection was carried out through narrative interviews with academics in two contrasting English Universities. Findings, or areas for reflection, have emerged about the constraints and enablements academics perceive in respect of their professional development. In particular, themes such as the significance of professional status; misaligned initiatives and priorities; the influence of supportive networks; and emergent personal, individual concerns have surfaced. The conclusion is drawn that the significance of agency raises the importance of responding to the âvoices from belowâ
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