EXCEL through IoT (Exploring Cognitive and Emotional Learning through IOT)

Cognitive Learning is a process that involves learner’s knowledge into consideration. It involves the use of human brain. These days understanding students’s emotional state of mind is one of the research area where student face problems in tackling academic tasks. It has been observed that emotions are a crucial part of students' psychosomatic life, and that they may strongly influence academic motivation, cognitive strategies of learning and achieving the desired results.So, our research is to augment student learning and teacher instruction by giving the real-time reaction of students' state of mind, so that teacher can engage students in the learning processes, help them to learn or use the brain in much and far better way to relate thing with the previous one while learning something new.

GROWTH AND DEVELOPMENTIN CHILDREN- AN AYURVEDA REVIEW

The emotional, social and physical development of young children has a direct effect on their overall development and on the adult, they will become. That is why understanding the need to invest in very young children is so important, so as to maximize their future well-being. From above description it is very clear that, childhood is very crucial time period of life, therefore, Ayurveda Acharyas have very well identified the importance of child growth and development and differentiated the health and diseases of children from adult. Ayurveda has established the independent branch for child rearing practices and treatment of childhood diseases and named as Kaumarabhritya. Acharya Kashyapa has described the care of the child right from the gestational age during pregnancy, during labour and after the birth up to the age of sixteen years of life. If one closely observed the chapters of Kashyapa Samhita keenly, one can find a central theme behind all the principles of Ayurveda practices. That central theme is the growth of baby. All the Samskara mentioned in Ayurveda, are child rearing measures and treatment protocols focusing on the growth of baby, and planned systematically without hampering or altering the growth of the child. Also, growth assessment in children has been very well described by Ayurveda acharyas

A REVIEW ON ANALYTICAL METHOD DEVELOPMENT AND VALIDATION

The top objective of any pharmaceutical industry is to produce products of necessary characteristic and quality reliably, in a cost-effective manner. Development of a method is essential for discovery, development, and evaluation of medicines in the pharmaceutical formulation. The main aim of this review article was to check the development and validation of the procedure employed for the medication from the starting of the formulation to the complete commercial batch of product. At the point when an analytical technique is applied to produce outcomes for the quality of medicine associated samples, it is necessary that the outcomes are reliable. In the pharma industry, validation policy is documented for how to perform validation, types of validation and validation policy are complied with the necessities of good manufacturing practice (GMP) regulations. Validation is very important for the effective running of the pharmaceutical firms. At every stage from raw material to the finished, stability, everywhere validation was performed. The method was developed properly, and validation parameters are explained in terms of accuracy, specificity, precision, limit of detection (LOD), limit of quantitation (LOQ), ruggedness, robustness, and system suitability testing with the example of certain drugs. All validation parameters are used in the routine and stability analysis

MODE OF ACTION OF AMRITADYA GUGGULU IN THE MANAGEMENT OF STHOULYA W.S.R TO OBESITY

Obesity (Sthoulya) is the major and basic cause of lifestyle disorders like Diabetes mellitus (T2DM), Coronary heart disease (CHD), Hypertension. Obesity (Sthaulya) is increasing at an alarming rate in developed industrialized countries which are undergoing rapid nutrition and lifestyle transition. Obesity is one of the most effective diseases which affect someone’s social, physical and mental status. In Ayurveda, Sthoulya (Obesity) is regarded as Medoroga, a disorder of Meda Dhatu, which includes fat tissue and fat metabolism. According to Ayurveda, Sthoulya begins with an imbalance of Doshas (Vata, Pitta and Kapha), Agni (digestive fire), Malas (waste products) or an imbalance of Srotas (microcirculatory channels). This collection of imbalances then interferes with the formation of tissues or Dhatus and leads to a tissue imbalance that we experience as excess weight. Overweight and obesity are linked to more deaths worldwide than underweight. Overall, about 13% of the world adult population (11% of men and 15% of women) was obese in 2016. The worldwide prevalence of obesity nearly tripled between 1975 and 2016. Amritadya Guggulu possesses Rasa- Katu, Tikta, Kashaya, Guna- Laghu, Ruksha and Virya- Ushna, Vipaka- Katu, Dosha Karma- Kapha Vatashamaka is effective in the management of Sthoulya. By virtue of its Rasapanchaka, contents of drug are very well indicated in Kapha predominant pathologies. Due to this property, it breaks the Samprapti of Sthoulya. Hence the present attempt is done to encompass the up to date comprehensive literature to study the mode of action of Amritadya Guggulu in the management of Sthoulya w.s.r. to Ayurvedic properties and modern pharmacology

STUDY OF PANCHVALKAL KASAYA IN VAGINAL DISCHARGE W.S.R TO ANTIMICROBIAL PROPERTIES

Vaginal Discharge is a common complaint of women coming for medical consultation, it is characterized by discharge per vagina, with itching. It is very common in developing countries like India where unhygienic condition are prevalent, Stressful Modern life styles, Food Habits, Social status. It is common problem which affect women during reproductive age. WHO has estimated that there are 333 million new cases of curable Vulvovaginal infections per year. Many formulations have been mentioned in Ayurvedic texts for treatment of Yonigatasrava. Panchvalkal has been explained in Bhavprakash. The main objective of this review article is to discuss the thereupatic uses of Panchvalkal in various diseases and to discuss the different pharmacological properties and thereupatic uses of Panchvalkal. The selected drug is found to be effective in vaginal discharge w.s.r. to its Antimicrobial properties. It helps in eliminating symptoms like Srava, Kandu, Dorgandhya, Vedana etc. it has Kashya and Katu Properties. These Gunas are effective on vitiated Kapha and normalize it. The present attempt to encompass the up to date comprehensive literature to Study the mode of action of Panchvalkal in vaginal discharge w.s.r. to Ayurvedic properties and Modern pharmacology

Experimental Models on Diabetes: A Comprehensive Review

Present world scenario globally, upto 2010, around 285 million people suffering from Type 2 diabetes making up about 90% of the cases. According to statistics, by 2030, this number is estimated to almost double. Diabetes mellitus occurs throughout the world, but is more common (especially Type 2) in the more developed countries. The greatest increase in prevalence is, however, expected to occur in Asia and Africa, where most patients will probably be found by 2030. The aim of this review is to summarize several studies done for the discovery of new drug using different animal models for in vivo studies (chemical, surgical, and genetic models ) & in vitro models (glucose uptake, pancreatic islet cell lines and  insulin secretion)

ROLE OF AHARA AS A PRIME ETIOLOGICAL FACTOR IN THE MANIFESTATION OF DISEASE

Ayurveda considers Ahara (food) as one of the three supporting pillars. Food has been given prime importance since Vedic Period. It is considered as Brahma in Upanishad. Acharaya Kashyapa gives it the name Mahabhaisajya. This is responsible for the growth, development and enhancement of Ojas. The body as well as diseases; both psychological and lifestyle disorders like Heart disease, Obesity, Diabetes, Hypertension and Cancer being the major health problems are formed by food, wholesome and unwholesome food are responsible for happiness and misery respectively. The disease can be cured without any medication by just following wholesome regimen, whereas even hundreds of medicines cannot be cure a disease in absence of wholesome regimen. Ahara rasa which is formed from ingested diet nourished not only our body but also nourished mind and sensory organs. Ayurveda describes that Deha is made up of Ahara and the Vyadhi also. According to Laulimbaraja Pathya is the secret of healthiness likewise Apathya is the root cause of all diseases. Ayurvedic Acharayas describes importance of Ahara differently especially in Brihatrayee, a special chapter has been described for Annapana Vidhi. The principle of dietetics and nutrition in Ayurvedic system of medicine include different classes of Ahara i.e. eating and drinking items, principle of Pathyapathya (wholesome and unwholesome diet), discipline of eating (Ashta Ahara Vidhi Visheshayatan, Dvadasha Asana Vidhi etc.), Viruddha Ahara (incompatible diet). Ashta Ahara Vidhi Visheshayatan includes eight discipline of eating and Dvadasha Asana Vidhi includes the twelve discipline of eating as described by Acharya Charaka and Sushruta respectively and is very important in daily life for promotion of positive health

Skin Cancer Detection using Deep Neural Networks

Cancer is the most dangerous and stubborn disease known to mankind. It accounts for the most deaths caused by any disease. However, if detected early this medical condition is not very difficult to defeat. Tumors which are cancerous grow very rapidly and spread into different parts of the body and this process continues until that tumor spreads in the entire body and ultimately our organs stop functioning. If any tumor is developed in any part of our body it requires immediate medical attention to verify that the tumor is malignant(cancerous) or Benign(non-cancerous). Until now if any tumor has to be tested for malignancy a sample of tumor should be extracted out and then tested in the laboratory. But using the computational logic of Deep Neural Networks we can predict that the tumor is malignant or Benign by only a photograph of that tumor. If cancer is detected in early stage chances are very high that it can be cured completely. In this work, we detect Melanoma(Skin cancer) in tumors by processing images of those tumors

ROLE OF DIET AND LIFESTYLE IN THE PREVENTION OF MADHUMEHA

Ayurveda is a natural health care system that originated in India since the beginning of civilization. It is described by Acharaya Charak that to achieve Purushartha Chatushtaya, Arogya is necessary. Ayurveda strongly emphasize on preventive and promotive aspects of health rather than curative. The concepts of Dincharya, Ritucharya, Sadvritta, and Achara Rasayana along with guidelines for healthy diet and lifestyle is well established in Ayurveda, but in current scenario, hardly anyone aptly follow it. As a result, there is tremendous rise in lifestyle disorders as pandemics, Diabetes being most menacing among them. Diabetes is the fourth leading cause of global death by disease. Type 2 DM is responsible for approximately 90% of cases. In Ayurveda, Madhumeha one of the types of Vataja Prameha is compared to Diabetes Mellitus because of having similarities of disease in respect to etiopathogenesis, clinical features and prognosis. The main causes of Madhumeha are lack of exercise, improper food habits, excessive intake of food having Snigdha and Guru Guna and food which causes vitiation of Kapha Dosha. Modern therapeutics has many limitations but Ayurvedic principles of management can help the patient to control blood glucose level and have better routine life. So Ayurvedic lifestyle guidelines of adopting a healthy dietary pattern together with physical activity are valuable tools in the prevention of Madhumeha

Osteochondroma of talus and coalition of talocrural and intercuneiform joints - surgical management

Osteochondroma of talus is rare benign tumour. Tarsal coalition is a condition in which two or more tarsal bones are joined by non-osseous bridges of cartilage or fibrocartilage or by osseous bridges. Association of Talus osteochondroma with coalition of tarsal bones is extremely rare and has not been reported in the literature before. We are herewith reporting a case of osteochondroma of the talus with coalition of intercuneiform and talocrural joint in an 11-year-old male patient. Patient noticed swelling around ankle and pain on strenuous activities. CT scan confirmed the diagnosis. We did complete extraperiosteal excision of the osteochondroma and resection of tarsal coalition. Histopathological examination confirmed the diagnosis of osteochondroma. At one-year follow-up there is no recurrence of the tumour and patient had full range of motion. Complete extraperiosteal excision of the osteochondroma along with resection of tarsal coalition is important for complete eradication and preventing a recurrence