Estimation of flooded area in the Bahr El-Jebel basin using remote sensing techniques

International audienceIn spite of the importance of Sudd (swamp) area estimation for any hydrological project in the southern Sudan, yet, no abroad agreement on its size, due to the inaccessibility and civil war. In this study, remote sensing techniques are used to estimate the Bahr El-Jebel flooded area. MODIS-Terra (Moderate Resolution Imaging Spectroradiometer) level 1B satellite images are analyzed on basis of the unsupervised classification method. The annual mean of Bahr El-Jebel flooded area has been estimated at 20 400 km2, which is 96% of Sutcliffe and Park (1999) estimation on basis of water balance model prediction. And only, 53% of SEBAL (Surface Energy Balance Algorithm for Land) model estimation. The accuracy of the classification is 71%. The study also found the swelling and shrinkage pattern of Sudd area throughout the year is following the trends of Lake Victoria outflow patterns. The study has used two evaporation methods (open water evaporation and SEBAL model) to estimate the annual storage volume of Bahr El-Jebel River by using a water balance model. Also the storage changes due time is generated throughout the study years

A high resolution LC-MS targeted method for the concomitant analysis of 11 contraceptive progestins and 4 steroids.

In the context of hormonal contraception and hormone replacement therapy (HRT), many women are exposed to exogenous hormones. Current use of hormonal contraception with combined ethinyl estradiol and different progestins bestows a breast cancer relative risk (RR) of 1.2- while combined HRT has a RR of 2. Although these exposures present an important public health issue, little is known about the effects of individual progestins on the breast and other tissues. Increasing availability of large scale biobanks, high throughput analyses and data management tools enable ever expanding, sophisticated population studies. In order to address the impact of distinct progestins on various health indicators, it is desirable to accurately quantify progestins in clinical samples. Here we have developed and validated a high resolution liquid chromatography mass spectrometry (LC-MS) targeted method for the simultaneous quantification of 11 synthetic progestins widely used in oral contraceptives, gestodene, levonorgestrel, etonogestrel, chlormadinone acetate, cyproterone acetate, drospirenone, desacetyl norgestimate, medroxyprogesterone acetate, norethindrone, dienogest, nomegestrol acetate, and 4 endogenous steroid hormones, progesterone, testosterone, androstenedione, and cortisol in blood samples. This highly specific quantitative analysis with high resolution Orbitrap technology detects and quantifies 15 compounds using their internal standard counterparts in a single 12 min LC-MS run. Sensitivity is attained by the use of the instrument in targeted selected ion monitoring mode. Lower limit of quantitation ranges from 2.4 pg/ml for drospirenone to 78.1 pg/ml for chlormadinone acetate. The method provides comprehensive progestin panel measurements with as little as 50 μl of murine or human plasma

Deep Eutectic Solvents for Innovative Pharmaceutical Formulations

International audienc