Autofluorescent polarimetry in diagnostics of endometriosis and infertility

A new information about optical technique in diagnostics for the endometrium structure has been proposed. The model of Mueller-matrix description of mechanisms responsible for optical anisotropy of these objects (optical activity, birefringence as well as linear and circular dichroism) has been suggested. The ensemble of informationally topical azimuthally stable Mueller-matrix invariants has been determined. Using the statistical analysis of the distribution parameters, the objective criteria for differentiation of endometrium taken from healthy women and patients with endometriosis were determined. From the viewpoint of probative medicine, the operational characteristics (sensitivity, specificity and accuracy) of the information-optical method applied to Mueller-matrix mapping of endometrium histological section have been found and its efficiency in diagnostics of endometriosis and infertility has been demonstrated

POLARIZATION-CORRELATION MICROSCOPY OF HUMAN LIQUID POLYCRYSTALLINE FILMS IN INFERTILITY DIAGNOSIS

A new azimuthally stable polarimetric method for processing of microscopic images of optically anisotropic structures of different biological layers blood plasma is proposed. A new model of phase anisotropy definition of biological tissues by using superposition of Mueller matrices of linear birefringence and optical activity is proposed. The matrix element M 44 has been chosen as the main information parameter, which value is independent of rotation angle of both sample and probing beam polarization plane