La Investigación Administrativa en la Revista de Gestión y Política Pública, del Centro de Investigación y Docencia Económicas (CIDE).

El presente capítulo se divide en dos partes. En la primera se hace una breve descripción del origen y objetivos del CIDE, así como de los antecedentes y generalidades de Gestión y Políticas Públicas; mientras que en el segundo apartado se procede a desarrollar el análisis de los números que se publicaron entre 2004 y 2014, de acuerdo a los parámetros establecidos en el proyecto “La investigación en Administración Pública en México. Análisis comparativo de tres revistas especializadas en el periodo 2004-2014, con la metodología de Perry y Kraemer”.A fin de continuar con el proceso de análisis del tipo de investigación que se realiza sobre la Administración Pública en México, toca ahora el turno a la revista Gestión y Políticas Públicas, que edita el Centro de Investigación y Docencia Económicas (CIDE), que al cabo de casi 25 años, se ha colocado como una de las principales publicaciones en lengua española que, a nivel internacional, ofrece un espacio para difundir, investigaciones, tanto básicas, como aplicadas, en el campo de la Administración Pública

Reconocimiento de lengua de señas colombiana mediante redes neuronales convolucionales y captura de movimiento

Context: This article presents the design of a computational predictive model that facilitates the recognition of Colombian Sign Language (LSC) in a hotel and tourism environment. Method: Artificial intelligence techniques and deep neural networks were applied in the learning and prediction of gestures in real time, which allowed the construction of a tool to reduce the gap and strengthen communication. Convolutional neural network algorithms were applied to real-time data capture. Movement was captured using mobile device video cameras, thus obtaining the images that make up the data set. The images were used as training data for an optimal computational model that can predict the meaning of a newly presented image. Results: The performance of the model was evaluated using categorical measures and comparing different configurations for the neural network. In addition to this, everything is supported with the use of tools such as Tensorflow, OpenCV and MediaPipe. Conclusions: Finally, a model capable of identifying and translating 39 different signs between words, numbers and basic phrases focused on the hotel sector was obtained, where a success rate of 97.6% was obtained in a controlled use environment.  Contexto: Este articulo presenta el diseño de un modelo predictivo computacional que facilita el reconocimiento de la lengua de señas colombiana (LSC) en un entorno hotelero y turístico. Método: Se aplicaron técnicas de inteligencia artificial y redes neuronales profundas en el aprendizaje y la predicción de gestos en tiempo real, los cuales permitieron construir una herramienta para disminuir la brecha y fortalecer la comunicación. Se implementaron algoritmos de redes neuronales convolucionales sobre captura de datos en tiempo real. Se capturó movimiento mediante cámaras de video de dispositivos móviles; así, se obtuvieron las imágenes que forman el conjunto de datos. Las imágenes se utilizaron como datos de entrenamiento para un modelo computacional óptimo que puede predecir el significado de una imagen recién presentada. Resultados: Se evaluó el rendimiento del modelo usando medidas categóricas y comparando diferentes configuraciones para la red neuronal. Adicional a esto, todo está soportado con el uso de herramientas como Tensorflow, OpenCV y MediaPipe. Conclusiones: Se obtuvo un modelo capaz de identificar y traducir 39 señas diferentes entre palabras, números y frases básicas enfocadas al sector hotelero, donde se logró una tasa de éxito del 97,6 % en un ambiente de uso controlado

Recursos docentes audiovisuales aplicados a la conservación del patrimonio

El uso de la tecnología como recurso didáctico nos permite abordar aspectos relativos a la conservación y restauración del patrimonio cultural de una forma novedosa, accesible, ágil y dinámica. Tras el desarrollo, edición y publicación de cuatro experiencias basadas en la realidad aumentada, las imágenes superdimensionables, el modelado 3D o la realidad virtual, así como su uso y aplicación en el entorno universitario, exponemos una valoración de los resultados obtenidos y de las aplicaciones prácticas que estas herramientas tecnológicas ofrecen a los estudiantes del grado en conservación- restauración, de otras titulaciones aines; así como, para el especialista en patrimonio o el público en general.The use of technology as a teaching resource allows us to address aspects related to the conservation and restoration of cultural heritage in a new, accessible, agile and dynamic way. After the development, editing and publication of four experiences based on augmented reality, super-dimensional images, 3D modeling or virtual reality, as well as their use and application in the university environment, we present an assessment of the results obtained and the applications practices that these technological tools ofer to students of the degree in conservation-restoration, of other related degrees; as well as, for the heritage specialist or the general public

The Toronto Mindfulness Scale and the State Mindfulness Scale: psychometric properties of the Spanish versions

Objectives The Toronto Mindfulness Scale (TMS) and the State Mindfulness Scale (SMS) are two relevant self-report measures of state mindfulness. The purpose of this study was to examine the internal structure and to offer evidence of the reliability and validity of the Spanish versions of the TMS and SMS.MethodsData from six distinct non-clinical samples in Spain were obtained. They responded to the TMS (n = 119), SMS (n = 223), and measures of trait mindfulness, decentering, non-attachment, depression, anxiety, stress, positive and negative affect, self-criticism, and self-reassurance. The internal structure of the TMS and SMS was analyzed through confirmatory factor analysis. Reliability, construct validity, and sensitivity to change analyses were performed.ResultsThe correlated two-factor structure (curiosity and decentering) was the best-fitting model for the TMS (CFI = 0.932; TLI = 0.913; RMSEA = 0.100 [0.077–0.123]; WRMR = 0.908). The bifactor structure (general factor, mindfulness of body, and mindfulness of mind) was the best-fitting model for the SMS (CFI = 0.961; TLI = 0.950; RMSEA = 0.096 [0.086–0.106]; WRMR = 0.993). Adequate reliability was found for both measures. The reliability of the SMS specific factors was very poor when controlling for the general factor. The patterns of correlations were mainly as expected and according to previous literature. The TMS and SMS have been able to detect state mindfulness changes after different meditation practices.ConclusionValidity evidence is provided to support the use of the TMS and SMS in Spanish populations, though the reliability of the SMS specific factors merit revision

Boletín MOMENTO ECONÓMICO, año 2, núms. 23-24, Julio-Agosto 2012.

Las campañas realizadas para las elecciones federales del pasado 1 de julio, pusieron en evidencia la necesidad de un amplio debate sobre cuál debe ser la estrategia a seguir para construir en México un proceso económico de desarrollo incluyente, sustentable y con equidad social. Fueron diversas variables las que pusieron de manifiesto la urgencia de avanzar en esta dirección: la ausencia de reflexión sobre el tema, la parcialidad de los enfoques y la falta de objetividad en la evaluación de los resultados del modelo aplicado en las tres últimas décadas, entre otras. Culminado el proceso electoral, a dos semanas de que el Tribunal Electoral del Poder Judicial de la Federación lo califique y a escasos tres meses de que dé inicio un nuevo mandato presidencial, el entorno económico nacional y mundial nos exigen, una vez más, reflexionar sobre la validez de la estrategia económica aplicada para promover el desarrollo y enfrentar la profunda crisis por la que atraviesa el sistema económico en su conjunto

Evaluation of diagnostic and prognostic candidate biomarkers in drug-induced liver injury vs. other forms of acute liver damage

Aims Detection and characterization of idiosyncratic drug-induced liver injury (DILI) currently rely on standard liver tests, which are suboptimal in terms of specificity, sensitivity and prognosis. Therefore, DILI diagnosis can be delayed, with important consequences for the patient. In this study, we aimed to evaluate the potential of osteopontin, cytokeratin-18 (caspase-cleaved: ccK18 and total: K18), α-glutathione-S-transferase and microRNA-122 as new DILI biomarkers. Methods Serial blood samples were collected from 32 DILI and 34 non-DILI acute liver injury (ALI) cases and a single sample from 43 population controls without liver injury (HLC) and analysed using enzyme-linked immunosorbent assay (ELISA) or single-molecule arrays. Results All biomarkers differentiated DILI and ALI from HLC with an area under receiver operator characteristic curve (AUC) value of >0.75 but were less efficient in distinguishing DILI from ALI, with ccK18 (0.79) and K18 (0.76) demonstrating highest potential. However, the AUC improved considerably (0.98) for ccK18 when comparing DILI and a subgroup of autoimmune hepatitis cases. Cytokeratin-18, microRNA-122 and α-glutathione-S-transferase correlated well with traditional transaminases, while osteopontin correlated most strongly with the international normalized ratio (INR). Conclusions ccK18 appears promising in distinguishing DILI from autoimmune hepatitis but less so from other forms of acute liver injury. Osteopontin demonstrates prognostic potential with higher levels detected in more severe cases regardless of aetiology.Consejería de Salud y Familia de la Junta de Andalucía, Grant/Award Numbers: PI 0274-2016, P18-RT-3364; Instituto de Salud Carlos III (ISCIII) cofounded by Fondo Europeo de Desarrollo Regional - FEDER, Grant/Award Numbers: PI19/00883, PI18/00901, UMA18-FEDERJA-193; Universidad de Málaga/CBUA for open access charge: Universidad de Málaga / CBUA. Funding for open access charge: Universidad de Málaga / CBU

Impact of operatoŕs experience on peri-procedural outcomes with Watchman FLX: Insights from the FLX-SPA registry

Background: The Watchman FLX is a device upgrade of the Watchman 2.5 that incorporates several design enhancements intended to simplify left atrial appendage occlusion (LAAO) and improve procedural outcomes. This study compares peri-procedural results of LAAO with Watchman FLX (Boston Scientific, Marlborough, Massachusetts) in centers with varying degrees of experience with the Watchman 2.5 and Watchman FLX. Methods: Prospective, multicenter, 'real-world' registry including consecutive patients undergoing LAAO with the Watchman FLX at 26 Spanish sites (FLX-SPA registry). Implanting centers were classified according to the center's prior experience with the Watchman 2.5. A further division of centers according to whether or not they had performed ≤ 10 or > 10Watchman FLX implants was prespecified at the beginning of the study. Procedural outcomes of institutions stratified according to their experience with the Watchman 2.5 and FLX devices were compared. Results: 359 patients [mean age 75.5 (SD8.1), CHA2DS2-VASc 4.4 (SD1.4), HAS-BLED 3.8(SD0.9)] were included. Global success rate was 98.6%, successful LAAO with the first selected device size was achieved in 95.5% patients and the device was implanted at first attempt in 78.6% cases. There were only 9(2.5%) major peri-procedural complications. No differences in efficacy or safety results according to the centeŕs previous experience with Watchman 2.5 and procedural volume with Watchman FLX existed. Conclusions: The Watchman FLX attains high procedural success rates with complete LAA sealing in unselected, real-world patients, along with a low incidence of peri-procedural complications, regardless of operatoŕs experience with its previous device iteration or the number of Watchman FLX devices implanted

Bosque de niebla. Gestión y educación ambiental como herramientas didácticas para su conservación

La investigación en estrategias de gestión en sistemas socioecológicos busca aportes al conocimiento para la protección de ecosistemas estratégicos como son los bosques de niebla y la comunicación que estos ejercen con la ciudad-región, como es el caso de bosque de niebla en el sector del Salto del Tequendama. Para ello se plantean diferentes miradas investigativas de diferentes profesionales que participaron en calidad de coinvestigadores, cuyos aportes significativos en las diferentes temáticas a los procesos investigativos, a través de diferentes aristas epistemológicas, se articulan alrededor de los siguientes ejes: ecología, ecopedagogía y recursos naturales, aulas ambientales, modelos pedagógicos en educación ambiental, didácticas ambientales y elementos de TIC. Todas estas son herramientas para desarrollar la educación ambiental y las experiencias pedagógicas por parte de algunos docentes en colegios del departamento de Cundinamarca, quienes dinamizaron proyectos Praes y experiencias educativas para la conservación de los recursos naturales. El elemento común en esto es conseguir que los actores de las comunidades educativas generaran procesos en los que la educación ambiental facilite y genere espacios participativos para el fomento de la protección y conservación de los recursos naturales, en especial de los bosques de niebla

Clonal chromosomal mosaicism and loss of chromosome Y in elderly men increase vulnerability for SARS-CoV-2

The pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2, COVID-19) had an estimated overall case fatality ratio of 1.38% (pre-vaccination), being 53% higher in males and increasing exponentially with age. Among 9578 individuals diagnosed with COVID-19 in the SCOURGE study, we found 133 cases (1.42%) with detectable clonal mosaicism for chromosome alterations (mCA) and 226 males (5.08%) with acquired loss of chromosome Y (LOY). Individuals with clonal mosaic events (mCA and/or LOY) showed a 54% increase in the risk of COVID-19 lethality. LOY is associated with transcriptomic biomarkers of immune dysfunction, pro-coagulation activity and cardiovascular risk. Interferon-induced genes involved in the initial immune response to SARS-CoV-2 are also down-regulated in LOY. Thus, mCA and LOY underlie at least part of the sex-biased severity and mortality of COVID-19 in aging patients. Given its potential therapeutic and prognostic relevance, evaluation of clonal mosaicism should be implemented as biomarker of COVID-19 severity in elderly people. Among 9578 individuals diagnosed with COVID-19 in the SCOURGE study, individuals with clonal mosaic events (clonal mosaicism for chromosome alterations and/or loss of chromosome Y) showed an increased risk of COVID-19 lethality