Supported accommodation evaluation framework (SAEF) guide

High hopes for the NDIS are that people with disability will be able to live as independently as they choose, with the housing of their choice, and with the paid support that suits their preferences and life goals. Research conducted by the Social Policy Research Centre for the NSW government about disability housing support that is like the NDIS found that most people did achieve some positive outcomes. Least change was evident in people’s interpersonal relationships and employment, and some people did not live in housing that met their needs.&nbsp

Is investment in Indigenous land and sea management going to the right places to provide multiple co-benefits?

Indigenous land and sea management (ILSM) has been the focus of large government investment in Australia and globally. Beyond environmental benefits, such investments can deliver a suite of social, cultural and economic co-benefits, aligning with the objectives of Indigenous communities and of governments for culturally appropriate socio-economic development. Nevertheless, there have been very few studies done on the spatial distribution of this investment and the extent to which its associated co-benefits address socio-economic disadvantage, which is unevenly distributed across Australia. This study draws on Australian ILSM programmes to examine the spatial and temporal distribution of investment for ILSM between 2002–2012 and considers implications for the distribution of associated co-benefits. Mapping and analysis of 2600 conservation projects revealed that at least $462M of investment in ILSM projects had occurred at 750 discrete sites throughout Australia. More than half of this investment in ILSM has been concentrated in northern Australia, in disadvantaged remote and very remote areas where a high percentage of the population is Indigenous, and Indigenous land ownership extensive. Our research has shown that ILSM investment has successfully been spatially distributed to areas with high needs for multiple social, economic, environmental and health and well-being co-benefit outcomes

Self-Esteem in Second Life: An inWorld Group Intervention for Women with Disabilities

We are developing and investigating the feasibility of a self-esteem enhancement intervention in Second Life for women with physical disabilities. We adapted the curriculum of a previously tested workshop intervention to include features unique to this environment. Results of the beta test were very positive. Everyone involved showed considerable enthusiasm for exploring the new world of SL. The group leaders were challenged to resolve technical problems on every occasion, but these diminished and were perceived as manageable as the intervention progressed. Beta testers gave positive ratings to the information presented, organization, and usefulness of the intervention and found it very enjoyable although fatigue and stress limited the participation of some. They appreciated the use of Internet technology as an accommodation to their disability, in place of requiring transportation and additional energy expenditure to attend face-to-face meetings. Research issues related to engagement, measurement, and participant safety, as well as future research directions, are discussed. We conclude that SL has great potential for delivering health promotion interventions to women with physical disabilities

Guidelines for OLAC Video Game Genre Terms (olacvggt)

A thesaurus of video game genre terms with a corresponding MARC authority record

The Grizzly, February 7, 2013

Trustees Plan the Future of Ursinus • Forum Changes Time, Place • Graduation Speakers Selected • Writing Center to Expand Resources • New Exhibit at Berman Museum of Art • Summer Internship Profile • Students Set to Perform Noises Off on February 20 • Students Discuss Queer Life on Liberal Arts Campus • Opinion: U.S. Gun Legislation Needs to be Amended; Our Reliance on Technology is Changing the Way we Think • February 1 Banner Day for Spring Athletes • Swimming Sweeps WAChttps://digitalcommons.ursinus.edu/grizzlynews/1874/thumbnail.jp

Threonine 149 Phosphorylation Enhances ΔFosB Transcriptional Activity to Control Psychomotor Responses to Cocaine

Stable changes in neuronal gene expression have been studied as mediators of addicted states. Of particular interest is the transcription factor ΔFosB, a truncated and stable FosB gene product whose expression in nucleus accumbens (NAc), a key reward region, is induced by chronic exposure to virtually all drugs of abuse and regulates their psychomotor and rewarding effects. Phosphorylation at Ser[superscript 27] contributes to ΔFosB's stability and accumulation following repeated exposure to drugs, and our recent work demonstrates that the protein kinase CaMKIIα phosphorylates ΔFosB at Ser[superscript 27] and regulates its stability in vivo. Here, we identify two additional sites on ΔFosB that are phosphorylated in vitro by CaMKIIα, Thr[superscript 149] and Thr[superscript 180], and demonstrate their regulation in vivo by chronic cocaine. We show that phosphomimetic mutation of Thr[superscript 149] (T149D) dramatically increases AP-1 transcriptional activity while alanine mutation does not affect transcriptional activity when compared with wild-type (WT) ΔFosB. Using in vivo viral-mediated gene transfer of ΔFosB-T149D or ΔFosB-T149A in mouse NAc, we determined that overexpression of ΔFosB-T149D in NAc leads to greater locomotor activity in response to an initial low dose of cocaine than does WT ΔFosB, while overexpression of ΔFosB-T149A does not produce the psychomotor sensitization to chronic low-dose cocaine seen after overexpression of WT ΔFosB and abrogates the sensitization seen in control animals at higher cocaine doses. We further demonstrate that mutation of Thr[superscript 149] does not affect the stability of ΔFosB overexpressed in mouse NAc, suggesting that the behavioral effects of these mutations are driven by their altered transcriptional properties