Simulations of Melting of Encapsulated CaCl2·6H2O for Thermal Energy Storage Technologies

We present in this work simulations using the finite difference approximation in 2D for the melting of an encapsulated phase-change material suitable for heat storage applications; in particular, we study CaCl2·6H2O in a cylindrical encapsulation of internal radius 8 mm. We choose this particular salt hydrate due to its availability and economic feasibility in high thermal mass building walls or storage. Considering only heat conduction, a thermostat is placed far from the capsule, providing heat for the melting of the phase-change material (PCM), which is initially frozen in a water bath. The difference in density between the solid and liquid phases is taken into account by considering a void in the solid PCM. A simple theoretical model is also presented, based on solving the heat equation in the steady state. The kinetics of melting is monitored by the total solid fraction and temperatures in the inner and outer surfaces of the capsule. The effect of different parameters is presented (thermostat temperature, capsule thickness, capsule conductivity and natural convection in the bath), showing the potential application of the method to select materials or geometries of the capsule

Phytochemical-Based Nanomaterials against Antibiotic-Resistant Bacteria: An Updated Review

Antibiotic-resistant bacteria (ARB) is a growing global health threat, leading to the search for alternative strategies to combat bacterial infections. Phytochemicals, which are naturally occurring compounds found in plants, have shown potential as antimicrobial agents; however, therapy with these agents has certain limitations. The use of nanotechnology combined with antibacterial phytochemicals could help achieve greater antibacterial capacity against ARB by providing improved mechanical, physicochemical, biopharmaceutical, bioavailability, morphological or release properties. This review aims to provide an updated overview of the current state of research on the use of phytochemical-based nanomaterials for the treatment against ARB, with a special focus on polymeric nanofibers and nanoparticles. The review discusses the various types of phytochemicals that have been incorporated into different nanomaterials, the methods used to synthesize these materials, and the results of studies evaluating their antimicrobial activity. The challenges and limitations of using phytochemical-based nanomaterials, as well as future directions for research in this field, are also considered here. Overall, this review highlights the potential of phytochemical-based nanomaterials as a promising strategy for the treatment against ARB, but also stresses the need for further studies to fully understand their mechanisms of action and optimize their use in clinical setting

Validation of a Device for the Ambulatory Monitoring of Sleep Patterns: A Pilot Study on Parkinson's Disease

The development of wearable devices has increase interest in the use of ambulatory methods to detect sleep disorders more objectively than those permitted by subjective scales evaluating sleep quality, while subjects maintain their usual lifestyle. This study aims to validate an ambulatory circadian monitoring (ACM) device for the detection of sleep and wake states and apply it to the evaluation of sleep quality in patients with Parkinson disease (PD). A polysomnographic validation study was conducted on a group of patients with different sleep disorders in a preliminary phase, followed by a pilot study to apply this methodology to PD patients. The ACM device makes it possible to estimate the main sleep parameters very accurately, as demonstrated by: (a) the lack of significant differences between the mean values detected by PSG and ACM in time in bed (TIB), total sleep time (TST), sleep efficiency (SE), and time awake after sleep onset (WASO); (b) the slope of the correlation lines between the parameters estimated by the two procedures, very close to 1, which demonstrates the linearity of the predictions; (c) the low bias value in the estimates obtained through ACM. Sleep in PD is associated with lower distal skin temperature, efficiency and overall sleep time; greater WASO, activity during sleep and duration of naps and a worse circadian function index. In summary, the ACM device has proven to be clinically useful to evaluate sleep in an objective manner, thanks to the integrated management of different complementary variables, having advantages over conventional actigraphy

Tree Cover Estimation in Global Drylands from Space Using Deep Learning

We are grateful to Javier Montes for providing help with the Python scripts to access Google Maps’ API.Accurate tree cover mapping is of paramount importance in many fields, from biodiversity conservation to carbon stock estimation, ecohydrology, erosion control, or Earth system modelling. Despite this importance, there is still uncertainty about global forest cover, particularly in drylands. Recently, the Food and Agriculture Organization of the United Nations (FAO) conducted a costly global assessment of dryland forest cover through the visual interpretation of orthoimages using the Collect Earth software, involving hundreds of operators from around the world. Our study proposes a new automatic method for estimating tree cover using artificial intelligence and free orthoimages. Our results show that our tree cover classification model, based on convolutional neural networks (CNN), is 23% more accurate than the manual visual interpretation used by FAO, reaching up to 79% overall accuracy. The smallest differences between the two methods occurred in the driest regions, but disagreement increased with the percentage of tree cover. The application of CNNs could be used to improve and reduce the cost of tree cover maps from the local to the global scale, with broad implications for research and management.S.T., E.G., D.A.-S., and F.H. were supported by the project DeepSCOP-Ayudas Fundación BBVA a Equipos de Investigación Científica en Big Data 2018. E.G. is supported by the European Research Council grant agreement 647038 (BIODESERT). S.T. is supported by the Ramón y Cajal Program of the Spanish Government (RYC-2015-18136). S.T., E.G., and F.H. were supported by the Spanish Ministry of Science under the project TIN2017-89517-P. D.A.-S., E.G., and J.C. received support from project ECOPOTENTIAL, funded by European Union Horizon 2020 Research and Innovation Program, under grant agreement No. 641762, and from European LIFE Project ADAPTAMED LIFE14 CCA/ES/000612. D.A-S, S.T. and E.G. received support from Programa Operativo FEDER-Andalucía 2014-2020 under project DETECTOR A-RNM-256-UGR18. D.A-S. received support from NASA’s Work Program on Group on Earth Observations—Biodiversity Observation Network (GEOBON) under grant 80NSSC18K0446

Medical Physics in Expertia Program

[EN] Dosimetry and Radiation Protection, and Nuclear Physics and Technology are among the optional subjects in the degree in Physics of the University of Zaragoza.  Both of them are taught by the Atomic, Molecular and Nuclear Area in the Faculty of Science. Since 2010, teaching staff on these subjects started to collaborate with a medical physics expert. The collaboration consisted of a seminar on Medical Physics and a guided tour to the clinical facilities. In these activities, the main tasks of a Medical Physicist and the way to access to the specialized training were explained. In 2015 University of Zaragoza launched the first call of the Expertia Program.  This educational program adds professional experience to the academic programs.  Since then, the teaching staff on Dosimetry and Radiation Protection, and Nuclear Physics and Technology have applied for the Educational Expertia (Expertia Docente) Program in all the editions and the collaboration has been enlarged to include several Radiation Oncologists’ experiences in the activities.http://ocs.editorial.upv.es/index.php/HEAD/HEAD18Jiménez, FJ.; García, E.; Ponce, JM.; Gascón, M.; Puertas, MDM.; Méndez, A. (2018). Medical Physics in Expertia Program. Editorial Universitat Politècnica de València. 287-294. https://doi.org/10.4995/HEAD18.2018.7980OCS28729

Interaction between interconnected and isolated grounding systems: a case study of transferred potentials

The effect caused by ground fault current in a complex system of interacting electrodes is theoretically studied. The calculation applies to a specific case in which a set of interconnected electrodes, which are part of a grounding facility network, are activated by a ground fault current. Transferred potentials to adjacent passive electrodes are calculated and the most relevant parameters of the electrode system are evaluated. Finally, the convenience of connecting the grounding electrodes is discussed

Diffusive and Arrestedlike Dynamics in Currency Exchange Markets

This work studies the symmetry between colloidal dynamics and the dynamics of the Euro–U.S. dollar currency exchange market (EURUSD). We consider the EURUSD price in the time range between 2001 and 2015, where we find significant qualitative symmetry between fluctuation distributions from this market and the ones belonging to colloidal particles in supercooled or arrested states. In particular, we find that models used for arrested physical systems are suitable for describing the EURUSD fluctuation distributions. Whereas the corresponding mean-squared price displacement (MSPD) to the EURUSD is diffusive for all years, when focusing in selected time frames within a day, we find a two-step MSPD when the New York Stock Exchange market closes, comparable to the dynamics in supercooled systems. This is corroborated by looking at the price correlation functions and non-Gaussian parameters and can be described by the theoretical model. We discuss the origin and implications of this analogy

El sueño como factor de riesgo en el avance de la miopía

Peer ReviewedPostprint (published version

Effect of Maraviroc Intensification on HIV-1-Specific T Cell Immunity in Recently HIV-1-Infected Individuals

Background The effect of maraviroc on the maintenance and the function of HIV-1-specific T cell responses remains unknown. Methods Subjects recently infected with HIV-1 were randomized to receive anti-retroviral treatment with or without maraviroc intensification for 48 weeks, and were monitored up to week 60. PBMC and in vitro-expanded T cells were tested for responses to the entire HIV proteome by ELISpot analyses. Intracellular cytokine staining assays were conducted to monitor the (poly)-functionality of HIV-1-specific T cells. Analyses were performed at baseline and week 24 after treatment start, and at week 60 (3 months after maraviroc discontinuation). Results Maraviroc intensification was associated with a slower decay of virus-specific T cell responses over time compared to the non-intensified regimen in both direct ex-vivo as well as in in-vitro expanded cells. The effector function profiles of virus-specific CD8+ T cells were indistinguishable between the two arms and did not change over time between the groups. Conclusions Maraviroc did not negatively impact any of the measured parameters, but was rather associated with a prolonged maintenance of HIV-1-specific T cell responses. Maraviroc, in addition to its original effect as viral entry inhibitor, may provide an additional benefit on the maintenance of virus-specific T cells which may be especially important for future viral eradication strategies