233 research outputs found
Charakterisierung einer horizontal transferierten Region im Escherichia coli Stamm ECOR31
Im Escherichia coli Stamm ECOR31 konnte erstmals eine atypische Insertionsstelle der weit verbreiteten Pathogenitätsinsel Yersinia-HPI beschrieben werden. Statt dem asnT-tRNA-Gen findet sich am Integrase-Ende der HPI eine weitere, offenbar horizontal transferierte Region, die RegX genannt wurde. Diese besitzt eine Größe von 24196 Basenpaaren und unterscheidet sich mit einem G+C-Gehalt von 47,9% vom E. coli-Kerngenom. Weder auf DNA noch auf Protein-Ebene existieren höhere Homologien zu E. coli-DNA.
Nach Anfertigung einer Cosmid-Bank wurde die gesamte Region sequenziert und annotiert. RegX weist eine mosaikartige Struktur auf, mit Punktmutationen, Deletionen und Insertionen. Sie besteht aus 22 offenen Leserastern und alle potentiellen Gene und deren Translationsprodukte wurden durch Vergleiche mit der NCBI-Datenbank charakterisiert. Die Transkription verschiedener Gen-Cluster und deren Operonstruktur wurde mittels RT-PCR nachgewiesen. Die DNA-Region enthält eine interessante Anhäufung von putativen Aufnahme-Systemen für divalente Metallionen, wie Eisen, Zink, Mangan. Zudem beheimatet die Region X Regulatorgene ähnlich zu Fur und Zur und Zink-abhängige Enzyme.
Im Gesamtvergleich der Region X ergeben sich die höchsten Homologien zu Teilen des Plasmids pLVPK von Klebsiella pneumoniae CG43 30. Anhand der strukturellen Unterschiede der Sequenzen mit Punktmutationen und Rekombinations-Ereignissen kann der anhaltende Wandel bakterieller Genome nachvollzogen werden.
Des Weiteren wurde die Verbreitung dieser Region unter klinisch relevanten Enterobacteriaceae und Pseudomonaceae untersucht. Von 530 gescreenten Bakterien konnte ein Klebsiella pneumoniae Stamm isoliert werden, der in der groben Struktur identisch zu der untersuchten Region von ECOR31 ist. In diesem Isolat, das aus der Blutkultur eines Patienten mit Sepsis stammt, konnte sowohl die gesamte Region X, als auch die benachbarte Yersinia-HPI und die atypische Insertionsstelle der HPI nachgewiesen werden. Es ist davon auszugehen, dass die untersuchte Region auf einem konjugativen Klebsiella-Plasmid lokalisiert ist und so zusammen mit der HPI horizontal zwischen verschiedenen Spezies ĂĽbertragen werden kann
On the symmetry of a Preisach map
At the very heart of the successful phenomenological model of magnetic
hysteresis there is the so called Preisach distribution. In the existing
literature it is implicitly assumed, that this distribution has a mirror
symmetry. We show, by simple and convincing example, that this common
assumption is plainly wrong. Dropping it, we gain the ability to model not only
the usual hysteresis loops (major and minor) more accurately than ever before,
but also those displaying the exchange bias effect, what is impossible within
the framework of the symmetrical Preisach model. It is hoped, that our
observation paves the way towards the unified description of all the hysteretic
systems, including, but not necessarily limited to, superconductors,
(multi)layered structures, nanocrystalline materials, patterned media, and -
perhaps - the other non-magnetic hysteretic phenomena.Comment: 4 pages, 2 figures. Presented at the European Conference "Physics of
Magnetism'05", Poznan (Poland), June 24-27, 2005. Accepted for publication in
physica status solidi (b) (C) 2005 WILEY-VCH Verlag GmbH & Co. KGaA, Weinhei
Subharmonics and Aperiodicity in Hysteresis Loops
We show that it is possible to have hysteretic behavior for magnets that does
not form simple closed loops in steady state, but must cycle multiple times
before returning to its initial state. We show this by studying the
zero-temperature dynamics of the 3d Edwards Anderson spin glass. The specific
multiple varies from system to system and is often quite large and increases
with system size. The last result suggests that the magnetization could be
aperiodic in the large system limit for some realizations of randomness. It
should be possible to observe this phenomena in low-temperature experiments.Comment: 4 pages, 3 figure
Theory of Thermal Remagnetization of Permanent Magnets
A self-consistent mean-field theory explaining the thermal remagnetization
(TR) of polycrystalline permanent magnets is given. The influence of the
environment of a grain is treated by an inclusion approximation, relating the
field inside the grain to the local field outside by means of an internal
demagnetization factor . For the switching fields and the fluctuations of
the local fields around the mean field Gaussian distributions of widths
\sigmas and \sigmaf resp. are assumed. The isothermal hysteresis curve, the
recoil curves, and the TR in dependence on the model parameters , \sigmas,
and \sigmaf are calculated. Furthermore, the influence of the initial
temperature and the strong dependence of the TR on the demagnetization factor
of the sample are studied, and it is shown that for reasonable parameter sets
TR effects up to 100 % are possible. The theoretical results correspond well
with the experimental situation.Comment: 28 pages, 9 figures, Latex2e, accepted for publication in JMM
Fingerprinting Hysteresis
We test the predictive power of first-oder reversal curve (FORC) diagrams
using simulations of random magnets. In particular, we compute a histogram of
the switching fields of the underlying microscopic switching units along the
major hysteresis loop, and compare to the corresponding FORC diagram. We find
qualitative agreement between the switching-field histogram and the FORC
diagram, yet differences are noticeable. We discuss possible sources for these
differences and present results for frustrated systems where the discrepancies
are more pronounced.Comment: 4 pages, 5 figure
Reversal-Field Memory in the Hysteresis of Spin Glasses
We report a novel singularity in the hysteresis of spin glasses, the
reversal-field memory effect, which creates a non-analyticity in the
magnetization curves at a particular point related to the history of the
sample. The origin of the effect is due to the existence of a macroscopic
number of "symmetric clusters" of spins associated with a local spin-reversal
symmetry of the Hamiltonian. We use First Order Reversal Curve (FORC) diagrams
to characterize the effect and compare to experimental results on thin magnetic
films. We contrast our results on spin glasses to random magnets and show that
the FORC technique is an effective "magnetic fingerprinting" tool.Comment: 4 pages, 6 figure
Stochastic model of hysteresis
The methods of the probability theory have been used in order to build up a
new model of hysteresis. It turns out that the reversal points of the control
parameter (e. g., the magnetic field) are Markov points which determine the
stochastic evolution of the process. It has been shown that the branches of the
hysteresis loop are converging to fixed limit curves when the number of cyclic
back-and-forth variations of the control parameter between two consecutive
reversal points is large enough. This convergence to limit curves gives a clear
explanation of the accommodation process. The accommodated minor loops show the
return-point memory property but this property is obviously absent in the case
of non-accommodated minor loops which are not congruent and generally not
closed. In contrast to the traditional Preisach model the reversal point
susceptibilities are non-zero finite values. The stochastic model can provide a
good approximation of the Raylaigh quadratic law when the external parameter
varies between two sufficiently small values.Comment: 13 pages, 14 figure
Return to return point memory
We describe a new class of systems exhibiting return point memory (RPM) that
are different from those discussed before in the context of ferromagnets. We
show numerically that one dimensional random Ising antiferromagnets have RPM,
when configurations evolve from a large field. However, RPM is violated when
started from some stable configurations at finite field unlike in the
ferromagnetic case. This implies that the standard approach to understanding
ferromagnetic RPM systems will fail for this case. We also demonstrate RPM with
a set of variables that keep track of spin flips at each site. Conventional RPM
for the spin configuration is a projection of this result, suggesting that spin
flip variables might be a more fundamental representation of the dynamics. We
also present a mapping that embeds the antiferromagnetic chain in a two
dimensional ferromagnetic model, and prove RPM for spin exchange dynamics in
the interior of the chain with this mapping
Barkhausen Noise in a Relaxor Ferroelectric
Barkhausen noise, including both periodic and aperiodic components, is found
in and near the relaxor regime of a familiar relaxor ferroelectric,
PbMgNbO, driven by a periodic electric field. The
temperature dependences of both the amplitude and spectral form show that the
size of the coherent dipole moment changes shrink as the relaxor regime is
entered, contrary to expectations based on some simple models.Comment: 4 pages RevTeX4, 5 figures; submitted to Phys Rev Let
Magnetic hysteresis in Ising-like dipole-dipole model
Using zero temperature Monte Carlo simulations we have studied the magnetic
hysteresis in a three-dimensional Ising model with nearest neighbor exchange
and dipolar interaction. The average magnetization of spins located inside a
sphere on a cubic lattice is determined as a function of magnetic field varied
periodically. The simulations have justified the appearance of hysteresis and
allowed us to have a deeper insight into the series of metastable states
developed during this process.Comment: REVTEX, 10 pages including 4 figure
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