Harvest: A Digital Object Search and Discovery System for Distributed Collections with Different File Types and Structures

The Harvest site, http://harvest.mannlib.cornell.edu is implemented using Fedora for data management, SOLR/Lucene for search, and Drupal for the user interface. Its goals are to provide an integrated search interface in which differences in format, structure and location are disguised in favor of treating objects that are conceptually alike as like, parallel objects. This is done by building Fedora content models that keep track of the complexity while providing services normalized to the objects' conceptual types; Lucene search documents that are fully normalized to hide implementation differences; and a Drupal front end that can treat all of the objects as generic objects until and unless specialized front-end services are built

Harvest: A Digital Object Search and Discovery System for Distributed Collections with Different File Types and Structures

The Harvest site, http://harvest.mannlib.cornell.edu is implemented using Fedora for data management, SOLR/Lucene for search, and Drupal for the user interface. Its goals are to provide an integrated search interface in which differences in format, structure and location are disguised in favor of treating objects that are conceptually alike as like, parallel objects. This is done by building Fedora content models that keep track of the complexity while providing services normalized to the objects' conceptual types; Lucene search documents that are fully normalized to hide implementation differences; and a Drupal front end that can treat all of the objects as generic objects until and unless specialized front-end services are built

Planning Information Infrastructure through a New Library Research Partnership: Interim Report, July 2005

This document is an interim report on a Small Grant for Exploratory Research (SGER). This interim report was submitted to the National Science Foundation in July 2005.The Cornell Language Acquisition Laboratory and Albert R. Mann Library are in the midst of developing an innovative collaboration between a research laboratory and an academic library to plan for the data preservation and discovery needs of the twenty-first century. Digital technology and internet communication now provide the opportunity to revolutionize the research process, through the ability to store, preserve, share, discover, and reanalyze vast amounts of data. While some disciplines, such as genomics or astronomy, have already developed sophisticated information technology infrastructure for these tasks, others are only beginning such work. In many, if not most research fields, it is especially difficult for those uninitiated to discover where data are located, what they describe, and how they may be used. This project has begun to tackle these issues by taking advantage of the library's existing expertise in preservation, archiving, and metadata creation, building on the existing ontology-software tools the library has developed, and introducing a new conceptual framework that divides the tasks of data sharing into discrete levels that may be managed and presented in defferent ways not only for different audiences but respecting political divisions and control issues that will always be present throughout the laboratories and institutions of academia.This material is based upon work supported by the National Science Foundation, Grant No. 0437603. Any opinions, findings, and conclusions or recommendations expressed in this material are those of the author(s) and do not necessarily reflect the views of the National Science Foundation

TEEAL and AGORA: Off-and online access to the scientific literature of agriculture for the developing world

TEEAL (The Essential Electronic Agricultural Library) and AGORA (Access to Global Online Research in Agriculture) are digital collections of scientific agricultural literature for the developing world. Through both, the agricultural research cycle in the developing world functions more effectively, including in areas where access to the internet is limited, slow, or unreliable, thanks to TEEAL's offline access. This paper discusses the programs' training, outreach, and usage and barriers to it, and the international partnerships that make them possible. Also profiled is the new AgriKnowledge database, which provides access to key unpublished agricultural content, including reports from the Bill & Melinda Gates Foundation's programs and projects

Living in the Post

30 Jahre nach dem ersten Aufkommen des Begriffes Postsozialismus widmet sich dieser Band den vielfältigen (Re)Konfigurationen, die das Konzept seither durchlaufen hat und fragt nach seinem gegenwärtigen analytischen Gehalt. Anhand unterschiedlicher Kontexte untersuchen die Autor*innen die multiplen Verwendungen von und Perspektiven auf das Konzept. Sie wenden sich verschiedenen Formen von (materiellem) Erbe, künstlerisch-aktivistischen Projekten des Erinnerns oder Ost/West-Machtdynamiken zu und diskutieren das spannungsvolle Verhältnis zu post- und dekolonialen Theorien. Den Rahmen bildet dabei ein Fokus auf Praktiken des Erinnerns, der Vergegenwärtigung von Vergangenem und seinem Wirken in die Zukunft.Thirty years after the emergence of the term postsocialism, this volume is dedicated to the multiple (re)configurations the concept has undergone since then and inquires its current analytical value. Looking at different contexts, the authors examine the multiple uses of and perspectives on the concept. They turn to various forms of (material) heritage, artistic-activist projects of remembering, or East-West power dynamics and discuss the ambivalent relationship to post- and decolonial theories. The articles are framed by a focus on practices of remembering, the presencing of the past and its impact on the future.Peer Reviewe

Over-expression of ST3Gal-I promotes mammary tumorigenesis

Changes in glycosylation are common in malignancy, and as almost all surface proteins are glycosylated, this can dramatically affect the behavior of tumor cells. In breast carcinomas, the O-linked glycans are frequently truncated, often as a result of premature sialylation. The sialyltransferase ST3Gal-I adds sialic acid to the galactose residue of core 1 (Galβ1,3GalNAc) O-glycans and this enzyme is over-expressed in breast cancer resulting in the expression of sialylated core 1 glycans. In order to study the role of ST3Gal-I in mammary tumor development, we developed transgenic mice that over-express the sialyltransferase under the control of the human membrane-bound mucin 1 promoter. These mice were then crossed with PyMT mice that spontaneously develop mammary tumors. As expected, ST3Gal-I transgenic mice showed increased activity and expression of the enzyme in the pregnant and lactating mammary glands, the stomach, lungs and intestine. Although no obvious defects were observed in the fully developed mammary gland, when these mice were crossed with PyMT mice, a highly significant decrease in tumor latency was observed compared to the PyMT mice on an identical background. These results indicate that ST3Gal-I is acting as a tumor promoter in this model of breast cancer. This, we believe, is the first demonstration that over-expression of a glycosyltransferase involved in mucin-type O-linked glycosylation can promote tumorigenesis

Finishing the euchromatic sequence of the human genome

The sequence of the human genome encodes the genetic instructions for human physiology, as well as rich information about human evolution. In 2001, the International Human Genome Sequencing Consortium reported a draft sequence of the euchromatic portion of the human genome. Since then, the international collaboration has worked to convert this draft into a genome sequence with high accuracy and nearly complete coverage. Here, we report the result of this finishing process. The current genome sequence (Build 35) contains 2.85 billion nucleotides interrupted by only 341 gaps. It covers ∼99% of the euchromatic genome and is accurate to an error rate of ∼1 event per 100,000 bases. Many of the remaining euchromatic gaps are associated with segmental duplications and will require focused work with new methods. The near-complete sequence, the first for a vertebrate, greatly improves the precision of biological analyses of the human genome including studies of gene number, birth and death. Notably, the human enome seems to encode only 20,000-25,000 protein-coding genes. The genome sequence reported here should serve as a firm foundation for biomedical research in the decades ahead

The Core Historical Literature Approach for Selection for Digitial Imaging

Chapter 4 of 8.The Core Historical Literature Approach is based on the principle that effective preservation plans should focus on a specific discipline as a whole rather than on the holdings of an individual library and features the collection of extensive evaluative information from scholars. These users of the literature provide their expert opinions regarding historical publications' relative value and importance. This results in ranked bibliographic lists, addressing the fact that the quantity of materials in many subject areas that is at risk for deterioration is far greater than can be handled by available preservation resources. Mann Library has successfully applied this approach to its digitized collections of agricultural literature, the Core Historical Literature of Agriculture (CHLA) (http://chla.library.cornell.edu/), and home economics literature, the Home Economics Archive: Research, Tradition, and History (HEARTH) (http://hearth.library.cornell.edu/).Cornell University Librar

The Core Historical Literature of Agriculture: Agricultural History Rejuvenated for Today's Users

This article has been accepted for publication by the Journal of Food and Agricultural Information, Haworth Press, 2005