Design of dimensional model for clinical data storage and analysis

Current research in the field of Life and Medical Sciences is generating chunk of data on daily basis. It has thus become a necessity to find solutions for efficient storage of this data, trying to correlate and extract knowledge from it. Clinical data generated in Hospitals, Clinics & Diagnostics centers is falling under a similar paradigm. Patient’s records in various hospitals are increasing at an exponential rate, thus adding to the problem of data management and storage. Major problem being faced corresponding to storage, is the varied dimensionality of the data, ranging from images to numerical form. Therefore there is a need for development of efficient data model which can handle this multi-dimensionality data issue and store the data with historical aspect. For the stated problem lying in façade of clinical informatics we propose a clinical dimensional model design which can be used for development of a clinical data mart. The model has been designed keeping in consideration temporal storage of patient's data with respect to all possible clinical parameters which can include both textual and image based data. Availability of said data for each patient can be then used for application of data mining techniques for finding the correlation of all the parameters at the level of individual and population

Young people's knowledge, attitude, and behaviour on STI/HIV/AIDS in the context of Nepal: a systematic review.

Sexual and reproductive health of young people has become a major health problem in recent decades. Recent and rapidly increasing Human Immune Deficiency Virus (HIV) rates show an urgent need for Sexually Transmitted Infections (STIs) and HIV prevention interventions in Nepal

Water poverty in the northeastern hill region (India): potential alleviation through multiple-use water systems: cross-learnings from Nepal Hills

Water poverty index / Construction / Multiple use / Water storage / Farming systems / Villages / Social aspects / Drip irrigation / India / Nepal / Nagaland / Mon district / Lampong Sheanghah

COMPARATIVE PHYSICOCHEMICAL, PHYTOCHEMICAL AND HIGH PERFORMANCE THIN LAYER CHROMATOGRAPHY EVALUATION OF HEART WOOD AND SMALL BRANCHES OF AQUILARIA AGALLOCHA ROXB.

Aquilaria agallocha Roxb. commonly called as Agaru is a medicinal plant. Heartwood of this tree is widely used in Ayurveda for various diseases. Removal of heart wood from trunk of this tree may make this plant weak and susceptible to damage due to which availability of this plant may be difficult in near future. Present study outlines the concept of plant part substitution. Heart wood and small branches of A. agallocha are compared on the basis of physicochemical analysis, phytochemical analysis, total phenolic contents, total flavonoid contents and high performance thin layer chromatography (HPTLC) to evaluate the possibilities of using small branches instead of heart wood. Physicochemical parameters of heartwood and small branches and phytochemical analysis of n-hexane, ethyl acetate and ethanol extract of both heart wood and small branches were carried out using standard methods. Total phenolics and total flavonoids were estimated spectrophotometrically using Folin-ciocalteu assayand aluminum chloride assaymethods, respectively. CAMAG HPTLC system equipped with semi-automatic applicator was used for HPTLC of n-hexane, ethyl acetate and ethanol extracts of stem bark and small braches using suitable mobile phases. Results of phytochemical analysis and HPTLC of n-hexane, ethyl acetate and ethanol extracts showed many similarities whichsuggest that small branches may have nearly similar active potency like heart wood and may be used as a substitute of heart wood after comparison and confirmation of same for pharmacological activities

Bianchi type-II cosmological model: some remarks

Within the framework of Bianchi type-II (BII) cosmological model the behavior of matter distribution has been considered. It is shown that the non-zero off-diagonal component of Einstein tensor implies some severe restriction on the choice of matter distribution. In particular for a locally rotationally symmetric Bianchi type-II (LRS BII) space-time it is proved that the matter distribution should be strictly isotropic if the corresponding matter field possesses only non-zero diagonal components of the energy-momentum tensor.Comment: 3 page

SUBSTITUTION OF ROOTS WITH SMALL BRANCHES OF RAUWOLFIA SERPENTINA FOR THERAPEUTIC USES - A PHYTOCHEMICAL APPROACH

Rauwolfia serpentina commonly called Sarpagandha is a medicinal plant widely used in Ayurveda. As per the Ayurvedic literature, roots of this plant are used in cardiac disorder, cancer, mental illness and psychiatric disorder. To collect roots for medicinal purpose whole plant is uprooted on a mass scale from their natural habitat which is leading to depletion of resources, due to which plant may be difficult in near future for use in traditional systems of medicine. Present study was carried out to assess possibilities of using small branches of R. serpentina in place of its roots which will help in conservation of this plant and availability of raw material for therapeutic purposes. Roots and small branches of R. serpentina are compared on the basis of physicochemical analysis, phytochemical analysis, total phenolic contents, total flavonoid contents and high performance thin layer chromatography (HPTLC) to evaluate the possibilities of using small branches in place of its roots. Results of phytochemical analysis and HPTLC of n-hexane, ethyl acetate and ethanol extracts showed many similarities whichsuggest that small branches may have nearly similar active constituents like roots and may be used as a substitute of roots after comparison and confirmation of same for pharmacological activities