Preliminary simulations of internal waves and mixing generated by finite amplitude tidal flow over isolated topography

Author Posting. © The Authors, 2005. This is the author's version of the work. It is posted here by permission of Elsevier B.V. for personal use, not for redistribution. The definitive version was published in Deep Sea Research Part II: Topical Studies in Oceanography 53 (2006): 140-156, doi:10.1016/j.dsr2.2005.09.014.Much recent observational evidence suggests that energy from the barotropic tides may be used for mixing in the deep ocean. Here the process of internal tide generation and dissipation by tidal flow over an isolated Gaussian topography is examined, using 2-dimensional numerical simulations employing the MITgcm. Four different topographies are considered, for five different amplitudes of barotropic forcing, thereby allowing a variety of combinations of key nondimensional parameters. While much recent attention has focused on the role of relative topographic steepness and height in modifying the rate of conversion of energy from barotropic to baroclinic modes, here attention is focused on parameters dependent on the flow amplitude. For narrow topography, large amplitude forcing gives rise to baroclinic responses at higher harmonics of the forcing frequency. Tall narrow topographies are found to be the most conducive to mixing. Dissipation rates in these calculations are most efficient for the narrowest topography.KH was supported by a Summer Student Fellowship at Woods Hole Oceanographic Institution. SL was supported by Office of Naval Research grant N00014-03-1-0336

Peripartum depression and anxiety as an integrative cross domain target for psychiatric preventative measures

Exposure to high levels of early life stress has been identified as a potent risk factor for neurodevelopmental delays in infants, behavioral problems and autism in children, but also for several psychiatric illnesses in adulthood, such as depression, anxiety, autism, and posttraumatic stress disorder. Despite having robust adverse effects on both mother and infant, the pathophysiology of peripartum depression and anxiety are poorly understood. The objective of this review is to highlight the advantages of using an integrated approach addressing several behavioral domains in both animal and clinical studies of peripartum depression and anxiety. It is postulated that a greater focus on integrated cross domain studies will lead to advances in treatments and preventative measures for several disorders associated with peripartum depression and anxiety. Exposure to high levels of early life stress has been identified as a potent risk factor for neurodevelopmental delays in infants, behavioral problems and autism in children, but also for several psychiatric illnesses in adulthood, such as depression, anxiety, autism, and posttraumatic stress disorder. Despite having robust adverse effects on both mother and infant, the pathophysiology of peripartum depression and anxiety are poorly understood. The objective of this review is to highlight the advantages of using an integrated approach addressing several behavioral domains in both animal and clinical studies of peripartum depression and anxiety. It is postulated that a greater focus on integrated cross domain studies will lead to advances in treatments and preventative measures for several disorders associated with peripartum depression and anxiety

La prescription de solutés de remplissage à l'Hôpital Bichat (enquête d'opinion et évaluation de la pratique et de la consommation au sein de services choisis)

PARIS7-Xavier Bichat (751182101) / SudocPARIS-BIUM (751062103) / SudocSudocFranceF

Influence of the Nature of the Amino Group in Highly Fluorescent Difluoroborates Exhibiting Intramolecular Charge Transfer

International audienc

Influence of the Nature of the Amino Group in Highly Fluorescent Difluoroborates Exhibiting Intramolecular Charge Transfer

A series of difluoroborates were synthesized from CH acids. All compounds were substituted with dialkylamino groups (NR₂). The lone electron pair of the nitrogen atom of this donor moiety is variably delocalized toward the difluoroborate core that acts as the electron acceptor. This was rationalized in light of the various geometries of the amino group. The degree of charge transfer was quantified on the basis of the results of time-dependent density functional theory calculations

Comparison of free-surface and rigid-lid finite element models of barotropic instabilities

The main goal of this work is to appraise the finite element method in the way it represents barotropic instabilities. To that end, three different formulations are employed. The free-surface formulation solves the primitive shallow-water equations and is of predominant use for ocean modeling. The vorticity-stream function and velocity-pressure formulations resort to the rigid-lid approximation and are presented because theoretical results are based on the same approximation. The growth rates for all three formulations are compared for hyperbolic tangent and piecewise linear shear flows. Structured and unstructured meshes are utilized. The investigation is also extended to time scales that allow for instability meanders to unfold, permitting the formation of eddies. We find that all three finite element formulations accurately represent barotropic instablities. In particular, convergence of growth rates toward theoretical ones is observed in all cases. It is also shown that the use of unstructured meshes allows for decreasing the computational cost while achieving greater accuracy. Overall, we find that the finite element method for free-surface models is effective at representing barotropic instabilities when it is combined with an appropriate advection scheme and, most importantly, adapted meshes