Combined Recording of Mechanically Stimulated Afferent Output and Nerve Terminal Labelling in Mouse Hair Follicle Lanceolate Endings

A novel dissection and recording technique is described for monitoring afferent firing evoked by mechanical displacement of hairs in the mouse pinna. The technique is very cost-effective and easily undertaken with materials commonly found in most electrophysiology laboratories, or easily purchased. The dissection is simple and fast, with the mechanical displacement provided by a generic electroceramic wafer controlled by proprietary software. The same software also records and analyses the electroneurogram output. The recording of the evoked nerve activity is through a commercial differential amplifier connected to fire-polished standard glass microelectrodes. Helpful tips are given for improving the quality of the preparation, the stimulation and the recording conditions to optimize recording quality. The system is suitable for assaying the electrophysiological and optical properties of lanceolate terminals of palisade endings of hair follicles, as well as the outcomes from their pharmacological and/or genetic manipulation. An example of combining electrical recording with mechanical stimulation and labeling with a styryl pyridinium vital dye is given

The Trouble with de Sitter Space

In this paper we assume the de Sitter Space version of Black Hole Complementarity which states that a single causal patch of de Sitter space is described as an isolated finite temperature cavity bounded by a horizon which allows no loss of information. We discuss the how the symmetries of de Sitter space should be implemented. Then we prove a no go theorem for implementing the symmetries if the entropy is finite. Thus we must either give up the finiteness of the de Sitter entropy or the exact symmetry of the classical space. Each has interesting implications for the very long time behavior. We argue that the lifetime of a de Sitter phase can not exceed the Poincare recurrence time. This is supported by recent results of Kachru, Kallosh, Linde and Trivedi.Comment: 15 pages, 1 figure. v2: added fifth section with comments on long time stability of de Sitter space, in which we argue that the lifetime can not exceed the Poincare recurrence time. v3: corrected a minor error in the appendi

The staggered domain wall fermion method

A different lattice fermion method is introduced. Staggered domain wall fermions are defined in 2n+1 dimensions and describe 2^n flavors of light lattice fermions with exact U(1) x U(1) chiral symmetry in 2n dimensions. As the size of the extra dimension becomes large, 2^n chiral flavors with the same chiral charge are expected to be localized on each boundary and the full SU(2^n) x SU(2^n) flavor chiral symmetry is expected to be recovered. SDWF give a different perspective into the inherent flavor mixing of lattice fermions and by design present an advantage for numerical simulations of lattice QCD thermodynamics. The chiral and topological index properties of the SDWF Dirac operator are investigated. And, there is a surprise ending...Comment: revtex4, 7 figures, minor revisions, 2 references adde

Fixing the conformal window in QCD

A physical characterization of Landau singularities is emphasized, which should trace the lower boundary N_f^* of the conformal window in QCD and supersymmetric QCD. A natural way to disentangle ``perturbative'' from ``non-perturbative'' contributions to amplitudes below N_f^* is suggested. Assuming an infrared fixed point persists in the perturbative part of the QCD coupling even below N_f^* leads to the condition \gamma(N_f^*)=1, where \gamma is the critical exponent. Using the Banks-Zaks expansion, one gets 4<N_f^*<6. This result is incompatible with the existence of an analogue of Seiberg duality in QCD. The presence of a negative ultraviolet fixed point is required both in QCD and in supersymmetric QCD to preserve causality within the conformal window. Evidence for the existence of such a fixed point in QCD is provided.Comment: 10 pages, 1 figure, extended version of a talk given at the QCDNET2000 meeting, Paris, September 11-14 2000; main new material added is evidence for negative ultraviolet fixed point in QC

Distributions of flux vacua

We give results for the distribution and number of flux vacua of various types, supersymmetric and nonsupersymmetric, in IIb string theory compactified on Calabi-Yau manifolds. We compare this with related problems such as counting attractor points.Comment: 43 pages, 7 figures. v2: improved discussion of finding vacua with discrete flux, references adde

Spiral Multi-component Structure in Pade - Approximant QCD

We present a graphical method of analyzing the infra-red fixed point structure of Pade approximant QCD. The analysis shows a spiral multi-component couplant structure as well as an infra-red attractor behavior of PQCD couplant for all flavors $0 \le N_{f} \le 16$.Comment: 78 pages, 4 tables, 44 graph

Testing the Gaussian expansion method in exactly solvable matrix models

The Gaussian expansion has been developed since early 80s as a powerful analytical method, which enables nonperturbative studies of various systems using `perturbative' calculations. Recently the method has been used to suggest that 4d space-time is generated dynamically in a matrix model formulation of superstring theory. Here we clarify the nature of the method by applying it to exactly solvable one-matrix models with various kinds of potential including the ones unbounded from below and of the double-well type. We also formulate a prescription to include a linear term in the Gaussian action in a way consistent with the loop expansion, and test it in some concrete examples. We discuss a case where we obtain two distinct plateaus in the parameter space of the Gaussian action, corresponding to different large-N solutions. This clarifies the situation encountered in the dynamical determination of the space-time dimensionality in the previous works.Comment: 30 pages, 15 figures, LaTeX; added references for section

Duality Twists, Orbifolds, and Fluxes

We investigate compactifications with duality twists and their relation to orbifolds and compactifications with fluxes. Inequivalent compactifications are classified by conjugacy classes of the U-duality group and result in gauged supergravities in lower dimensions with nontrivial Scherk-Schwarz potentials on the moduli space. For certain twists, this mechanism is equivalent to introducing internal fluxes but is more general and can be used to stabilize some of the moduli. We show that the potential has stable minima with zero energy precisely at the fixed points of the twist group. In string theory, when the twist belongs to the T-duality group, the theory at the minimum has an exact CFT description as an orbifold. We also discuss more general twists by nonperturbative U-duality transformations.Comment: 30 pages, harvmac, references and brief comments on gauged supergravity adde

Taking off the square root of Nambu-Goto action and obtaining Filippov-Lie algebra gauge theory action

We propose a novel prescription to take off the square root of Nambu-Goto action for a p-brane, which generalizes the Brink-Di Vecchia-Howe-Tucker or also known as Polyakov method. With an arbitrary decomposition as d+n=p+1, our resulting action is a modified d-dimensional Polyakov action which is gauged and possesses a Nambu n-bracket squared potential. We first spell out how the (p+1)-dimensional diffeomorphism is realized in the lower dimensional action. Then we discuss a possible gauge fixing of it to a direct product of $d$-dimensional diffeomorphism and n-dimensional volume preserving diffeomorphism. We show that the latter naturally leads to a novel Filippov-Lie n-algebra based gauge theory action in d-dimensions.Comment: 1+13 pages, No figure; Expanded, published version. Title change

Second and Third Order Observables of the Two-Matrix Model

In this paper we complement our recent result on the explicit formula for the planar limit of the free energy of the two-matrix model by computing the second and third order observables of the model in terms of canonical structures of the underlying genus g spectral curve. In particular we provide explicit formulas for any three-loop correlator of the model. Some explicit examples are worked out.Comment: 22 pages, v2 with added references and minor correction