The Ursinus Weekly, January 11, 1954

MSGA hears second case of cheating • Dr. James Martin is speaker at pre-med meeting • Dr. Garrett reads works of Proust • FTA hears talk by county school official • Alumni Office reports news of past graduates • Campus Chest reports total of $1,037.70 • F. W. Hankins is Bus. Ad. speaker • Baker, Miller debate on communist China in U.N. • Curtain Club schedules two one-act plays • French Club to discuss French art at next meeting • Greek columns • Editorials: Thanks, faculty • Recently announced engagements, pinnings • New Year\u27s congratulations • Examinations open for government positions • Practice teacher recalls woes, joys of high school life • Swami foresees U.C. fifty-four; Tells of strange revolutions • Matmen win thrilling Swarthmore opener: Dawkins, Paolone, Padula, Nunn pin; Briner decisions • Cubs remain undefeated in two league encounters • Cagers down Swarthmore; 77-67, on fast-breaking game • PMC and F&M defeat netmen • Knull illness hinders Bears • Philadelphia art museum exhibiting Van Gogh workshttps://digitalcommons.ursinus.edu/weekly/1486/thumbnail.jp

The Ursinus Weekly, November 16, 1953

Forum hears Norman Palmer talk on India • Honor system is MSGA topic at open discussion • U.C. group visits UN headquarters • Messiah features well-known soloists • Conditions in modern Austria revealed Monday by Thalburg • No easy answer seen by Chi Alpha Society • Faculty join students in show, Friday • Play polished by intense rehearsal • Music Club members attend harp concert • Dr. J. E. Wagner speaks, receives degree, Tuesday • High schools to tour campus • Doctors to appear at pre-med meeting • Dr. Yost presides at English lit reading • Pep talk on FTA affiliation given to campus members • Editorials: Education; Change in policy needed • Song and slogan spur Chest drive • Y sponsored work week commences November 30 • God and the atom to be coming attraction at vespers • Barbershop quartets present fine program • Beardwood Society plans field trip to exposition • Greek columns • Ursinus - F. & M. rivalry ends after fifty years • Variety of speakers highlight programs of past Founders Days • JVs lose second to strong Temple • Hockeyites down Temple in thrilling victory, 1-0 • Juniata defeats Bears for undefeated season • Cagemen initiate season tomorrow • Belles captain All-College teams • LaSalle defeats soccer team; Settles scores for Ursinus • Zartman, Settles, Dawkins score; Bakermen win, 6-2 • Writer satirizes sports jargonhttps://digitalcommons.ursinus.edu/weekly/1483/thumbnail.jp

An integrated spatio-temporal view of riverine biodiversity using environmental DNA metabarcoding 2

Anthropogenically forced changes in global freshwater biodiversity demands better monitoring approaches. Consequently, environmental DNA (eDNA) analysis is enabling ecosystem-scale biodiversity assessment, yet the accurate spatiotemporal resolution at which robust biodiversity information can be detected remains ambiguous. Here, using intensive, annual spatiotemporal eDNA sampling across space (five rivers in the USA and Europe, with an upper range of 20-35 km between samples), time (19 timepoints across 2017 to 2018) and environmental conditions (river flow, pH, conductivity, temperature and rainfall), we characterise the resolution at which information on diversity across the animal kingdom can be gathered from rivers. In space, beta diversity was mainly dictated by turnover, on a scale of tens of kilometres, highlighting that diversity measures are not confounded by eDNA from upstream. Fish communities showed nested assemblages along some rivers, coinciding with habitat use. Across time, seasonal life history events, including salmon and eel migration, were detected. Finally, effects of abiotic factors were taxon-specific, reflecting habitat filtering of communities rather than environmental effects on DNA molecules. We conclude that riverine eDNA metabarcoding can measure biodiversity at spatiotemporal scales relevant to species and community ecology, demonstrating its utility in delivering insights into river ecology during an epoch of environmental change

An integrated spatio-temporal view of riverine biodiversity using environmental DNA metabarcoding

Anthropogenically forced changes in global freshwater biodiversity demand more efficient monitoring approaches. Consequently, environmental DNA (eDNA) analysis is enabling ecosystem-scale biodiversity assessment, yet the appropriate spatio-temporal resolution of robust biodiversity assessment remains ambiguous. Here, using intensive, spatio-temporal eDNA sampling across space (five rivers in Europe and North America, with an upper range of 20–35 km between samples), time (19 timepoints between 2017 and 2018) and environmental conditions (river flow, pH, conductivity, temperature and rainfall), we characterise the resolution at which information on diversity across the animal kingdom can be gathered from rivers using eDNA. In space, beta diversity was mainly dictated by turnover, on a scale of tens of kilometres, highlighting that diversity measures are not confounded by eDNA from upstream. Fish communities showed nested assemblages along some rivers, coinciding with habitat use. Across time, seasonal life history events, including salmon and eel migration, were detected. Finally, effects of environmental conditions were taxon-specific, reflecting habitat filtering of communities rather than effects on DNA molecules. We conclude that riverine eDNA metabarcoding can measure biodiversity at spatio-temporal scales relevant to species and community ecology, demonstrating its utility in delivering insights into river community ecology during a time of environmental change

Long Noncoding RNA-Directed Epigenetic Regulation of Gene Expression Is Associated With Anxiety-like Behavior in Mice

Background RNA-directed regulation of epigenetic processes has recently emerged as an important feature of mammalian differentiation and development. Perturbation of this regulatory system in the brain may contribute to the development of neuropsychiatric disorders. Methods RNA sequencing was used to identify changes in the experience-dependent expression of long noncoding RNAs (lncRNAs) within the medial prefrontal cortex of adult mice. Transcripts were validated by real-time quantitative polymerase chain reaction and a candidate lncRNA, Gomafu, was selected for further investigation. The functional role of this schizophrenia-related lncRNA was explored in vivo by antisense oligonucleotide-mediated gene knockdown in the medial prefrontal cortex, followed by behavioral training and assessment of fear-related anxiety. Long noncoding RNA-directed epigenetic regulation of gene expression was investigated by chromatin and RNA immunoprecipitation assays. Results RNA sequencing analysis revealed changes in the expression of a significant number of genes related to neural plasticity and stress, as well as the dynamic regulation of lncRNAs. In particular, we detected a significant downregulation of Gomafu lncRNA. Our results revealed that Gomafu plays a role in mediating anxiety-like behavior and suggest that this may occur through an interaction with a key member of the polycomb repressive complex 1, BMI1, which regulates the expression of the schizophrenia-related gene beta crystallin (Crybb1). We also demonstrated a novel role for Crybb1 in mediating fear-induced anxiety-like behavior. Conclusions Experience-dependent expression of lncRNAs plays an important role in the epigenetic regulation of adaptive behavior, and the perturbation of Gomafu may be related to anxiety and the development of neuropsychiatric disorders

Performance of the ATLAS Electromagnetic Calorimeter End-cap Module 0

The construction and beam test results of the ATLAS electromagnetic end-cap calorimeter pre-production module 0 are presented. The stochastic term of the energy resolution is between 10% GeV^1/2 and 12.5% GeV^1/2 over the full pseudorapidity range. Position and angular resolutions are found to be in agreement with simulation. A global constant term of 0.6% is obtained in the pseudorapidity range 2.5 < eta < 3.2 (inner wheel)

Performance of the ATLAS electromagnetic calorimeter end-cap module 0

The construction and beam test results of the ATLAS electromagnetic end-cap calorimeter pre-production module 0 are presented. The stochastic term of the energy resolution is between 10% GeV^1/2 and 12.5% GeV^1/2 over the full pseudorapidity range. Position and angular resolutions are found to be in agreement with simulation. A global constant term of 0.6% is obtained in the pseudorapidity range 2.5 eta 3.2 (inner wheel)