1,159 research outputs found
There is an Answer to Bible Problems
Creation Noah\u27s Flood Age of the Earth Jonah and the Whale Joshua\u27s Long Day Virgin Birth Resurrectionhttps://digitalcommons.biola.edu/biola-pubs/1019/thumbnail.jp
Does God heal today?
But there is a true approach to the matter of healing from God. The Bible, which wonderfully answers every question in human life is not silent on the subject of divine healing. The need is to carefully study all related scriptures, asking God to reveal His truth.https://digitalcommons.biola.edu/biola-pubs/1028/thumbnail.jp
What the Bible says about divorce
https://digitalcommons.biola.edu/biola-pubs/1060/thumbnail.jp
'Unlicensed' natural killer cells dominate the response to cytomegalovirus infection.
Natural killer (NK) cells expressing inhibitory receptors that bind to self major histocompatibility complex (MHC) class I are 'licensed', or rendered functionally more responsive to stimulation, whereas 'unlicensed' NK cells lacking receptors for self MHC class I are hyporesponsive. Here we show that contrary to the licensing hypothesis, unlicensed NK cells were the main mediators of NK cell-mediated control of mouse cytomegalovirus infection in vivo. Depletion of unlicensed NK cells impaired control of viral titers, but depletion of licensed NK cells did not. The transfer of unlicensed NK cells was more protective than was the transfer of licensed NK cells. Signaling by the tyrosine phosphatase SHP-1 limited the proliferation of licensed NK cells but not that of unlicensed NK cells during infection. Thus, unlicensed NK cells are critical for protection against viral infection
Florida Audubon Society v. Bentsen: An Improper Application of Lujan to a Procedural Rights Plaintiff
Over the past twenty-five years, courts have applied the doctrine of standing in an increasingly stricter fashion upon environmental organizations. In 1996, the United States Court of Appeals for the District of Columbia issued the Florida Audubon Society v. Bentsen decision which sets virtually impossible standards for environmentalists seeking to bring procedural rights challenges under the National Environmental Policy Act (NEPA). The Bentsen court held that the plaintiffs did not have standing to file suit because they failed to demonstrate injury in fact and causation. This Case Note asserts that demonstrating the nature and likelihood of environmental injury is unduly burdensome to procedural rights plaintiffs who often lack the assistance of environmental impact statements. This Case Note provides background information on standing in general and on procedural rights standing under NEPA, focusing on the injury in fact requirement as applied to procedural rights cases including the hallmark Supreme Court decision in Lujan v. Defenders of Wildlife. The facts, procedural history, holding and reasoning of Bentsen will also be discussed. The analysis section examines the opinion of the Bentsen court with focus on its application of Lujan. This Case Note concludes that the Bentsen court misapplied Lujan and should have retained the circuit\u27s prior standing test for procedural rights plaintiffs. By ignoring the geographical nexus test of Lujan, the Bentsen opinion erodes the effectiveness of one of the most important environmental measures of the past generation
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Counterrealisation: Architectural Ideology from Plan to Project
This thesis constructs a genealogy of contemporary notions of architectural politics, through theoretical and disciplinary premises which have been inherited, consciously and unconsciously, from the 1960s and 1970s. In particular it focuses on currents within Italian political theory and historiography, which have been central to the development of self-reflexive discourses on the political possibilities and cultural agency of architecture over the past fifty years. Despite their prominence, these currents have a highly ambiguous relationship with the discipline to which they became linked. This can be seen clearly in the case of historian and theorist Manfredo Tafuri, whose work established the point of entry by which Western Marxist and Critical Theory perspectives confronted problems unique to the history of architecture. Over time, however, and through complex mediations, Tafuri’s work became internalised, its critical challenge integrated into a new institutional formation.
The significance of this reversal can be difficult to assess, both from within architectural discourse proper and from the above extra-disciplinary perspectives, for it falls within a shadow cast by the unique position “architecture” occupies within the larger field of cultural production and its critique. As the disciplinary agency of the architectural institution changed following the shifting conditions of modern development, the valence of architectural politics has changed as well, moving toward an increasingly negative or “critical” relation to the economic register from the late 1960s onward. The thesis constructs a definition of the resulting ideological notion—the “Project”—by which the architectural institution maintains its disciplinary autonomy, while laying claim to continued, or even increased, political agency. Such shifts of architectural ideology highlight the problematic position of critical and cultural practices within the political history of the twentieth and twenty-first century, demonstrating their ambivalence concerning the transition of Western capital into and then out of social democratic “planning.”
As a contribution to the history and theory of architecture, the thesis hones the critical and theoretical tools by which the ideological character of contemporary architecture can be understood. It constructs a periodisation that places this material within the larger historical trajectory of the architectural discipline, from the historical avant-gardes, through the Modern Movement, the neo-avant-garde, and the “post-critical,” to the present period of re-politicisation. However, it also illustrates the significance of architecture’s modern history to the larger debate concerning the political role of cultural production. A crucial figure in architectural discourse, Manfredo Tafuri’s larger significance to cultural criticism is expounded in the thesis. Conceptual and methodological results demonstrate the limitations of prevailing notions of “immanent critique,” when faced with contradictions revealed by the architectural case. Such contradictions return today with ever greater force when cultural agents, within architecture and without, seek to renew the bases of their agency in the face of political and economic crises without addressing this complex inheritance
I. The energies of ionic dissociation of gaseous salt molecules; II. The rate of diffusion of deuterium oxide in water, with a note on the refractive index of deuterium gas
1. An apparatus suitable for separating heavy
water from mixtures with organic compounds is
described.
2. The refractive index of heavy hydrogen at the
wavelength 5461 Å̱ is found to be appreciably
smaller than that of ordinary hydrogen and to
have the value 1.0001384
Obesity and outcomes of Kawasaki disease and COVID-19-related multisystem inflammatory syndrome in children
IMPORTANCE: Obesity may affect the clinical course of Kawasaki disease (KD) in children and multisystem inflammatory syndrome in children (MIS-C) associated with COVID-19.
OBJECTIVE: To compare the prevalence of obesity and associations with clinical outcomes in patients with KD or MIS-C.
DESIGN, SETTING, AND PARTICIPANTS: In this cohort study, analysis of International Kawasaki Disease Registry (IKDR) data on contemporaneous patients was conducted between January 1, 2020, and July 31, 2022 (42 sites, 8 countries). Patients with MIS-C (defined by Centers for Disease Control and Prevention criteria) and patients with KD (defined by American Heart Association criteria) were included. Patients with KD who had evidence of a recent COVID-19 infection or missing or unknown COVID-19 status were excluded.
MAIN OUTCOMES AND MEASURES: Patient demographic characteristics, clinical features, disease course, and outcome variables were collected from the IKDR data set. Using body mass index (BMI)/weight z score percentile equivalents, patient weight was categorized as normal weight (BMI \u3c85th percentile), overweight (BMI ≥85th to \u3c95th percentile), and obese (BMI ≥95th percentile). The association between adiposity category and clinical features and outcomes was determined separately for KD and MIS-C patient groups.
RESULTS: Of 1767 children, 338 with KD (median age, 2.5 [IQR, 1.2-5.0] years; 60.4% male) and 1429 with MIS-C (median age, 8.7 [IQR, 5.3-12.4] years; 61.4% male) were contemporaneously included in the study. For patients with MIS-C vs KD, the prevalence of overweight (17.1% vs 11.5%) and obesity (23.7% vs 11.5%) was significantly higher (P \u3c .001), with significantly higher adiposity z scores, even after adjustment for age, sex, and race and ethnicity. For patients with KD, apart from intensive care unit admission rate, adiposity category was not associated with laboratory test features or outcomes. For patients with MIS-C, higher adiposity category was associated with worse laboratory test values and outcomes, including a greater likelihood of shock, intensive care unit admission and inotrope requirement, and increased inflammatory markers, creatinine levels, and alanine aminotransferase levels. Adiposity category was not associated with coronary artery abnormalities for either MIS-C or KD.
CONCLUSIONS AND RELEVANCE: In this international cohort study, obesity was more prevalent for patients with MIS-C vs KD, and associated with more severe presentation, laboratory test features, and outcomes. These findings suggest that obesity as a comorbid factor should be considered at the clinical presentation in children with MIS-C
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