Intraocular-Orbital-Cerebral Toxoplasmosis as an Initial Presentation of AIDS (.pdf)

To Demonstrate Clinical Manifestations and Treatment Outcome of Intraocular-Orbital-Cerebral Toxoplasmosis in Newly Diagnosed HIV-Infected Patien

Atypical Central Retinal Artery Occlusion As The First Manifestation Of POEMS Syndrome

POEMS syndrome is a plasma cell disorder, which clinically manifests from paraneoplastic syndrome: polyradiculoneuropathy, organomegaly, endocrinopathy, monoclonal plasma cell disorder, and skin changes. The most common ocular manifestation is optic; disc edema, whereas other ocular manifestations; cystoid macular edema, serous macular detachment, anterior ischemic optic neuropathy, optic disc drusen, peripapillary choroidal neovascularization, uveitis and infiltrative orbitopathy, had also been reported

Health-related quality of life of daily-life-affected benign essential blepharospasm: Multi-center observational study

Purpose To compare Thais’ health-related quality of life (HRQOL) and severity grading, efficacy and safety in daily-life-affected benign essential blepharospasm (BEB) patients at baseline and after Botulinum toxin type A (BTX-A) treatment. Design Prospective-observational study. Participants BEB patients with Jankovic rating scale (JRS) at least 3 in both severity and frequency graded from 14 institutes nationwide were included from August 2020 to June 2021. Methods Demographic data, HRQOL evaluated by the Thai version of EQ-5D-5L and NEI-VFQ-25 questionnaires, and severity grading score evaluated by Jankovic rating scale (JRS) at baseline, 1, and 3 months after the treatment were collected. The impact of the BTX-A injections and their complications were recorded. Results 184 daily-life-affected BEB patients were enrolled; 159 patients (86.4%) had complete data with a mean age of 61.40±10.09 years. About 88.05% were female, and 10.1% were newly diagnosed. Most of the patients had bilateral involvement (96.9%) and 12.6% had history of BEB-related accident. After BTX-A treatment, HRQOL improved significantly in 4 dimensions of EQ-5D-5L, except self-care. The EQ_VAS (mean±SD) was 64.54±19.27, 75.13±15.37, 73.8±15.85 (pConclusion Daily-life-affected BEB impacted HRQOL in most dimensions from both generic and visual-specific questionnaires. BTX-A treatment not only decreased disease severity, but also improved quality of life