339 research outputs found
Spontaneous dog osteoarthritis — a One Medicine vision
Osteoarthritis (OA) is a global disease that, despite extensive research, has limited treatment options. Pet dogs share both an environment and lifestyle attributes with their owners, and a growing awareness is developing in the public and among researchers that One Medicine, the mutual co-study of animals and humans, could be beneficial for both humans and dogs. To that end, this Review highlights research opportunities afforded by studying dogs with spontaneous OA, with a view to sharing this active area of veterinary research with new audiences. Similarities and differences between dog and human OA are examined, and the proposition is made that suitably aligned studies of spontaneous OA in dogs and humans, in particular hip and knee OA, could highlight new avenues of discovery. Developing cross-species collaborations will provide a wealth of research material and knowledge that is relevant to human OA and that cannot currently be obtained from rodent models or experimentally induced dog models of OA. Ultimately, this Review aims to raise awareness of spontaneous dog OA and to stimulate discussion regarding its exploration under the One Medicine initiative to improve the health and well-being of both species
Gout in the UK and Germany: prevalence, comorbidities and management in general practice 2000–2005
Field-angle Dependence of the Zero-Energy Density of States in the Unconventional Heavy-Fermion Superconductor CeCoIn5
Field-angle dependent specific heat measurement has been done on the
heavy-fermion superconductor CeCoIn5 down to ~ 0.29 K, in a magnetic field
rotating in the tetragonal c-plane. A clear fourfold angular oscillation is
observed in the specific heat with the minima (maxima) occurring along the
[100] ([110]) directions. Oscillation persists down to low fields H << Hc2,
thus directly proving the existence of gap nodes. The results indicate that the
superconducting gap symmetry is most probably of dxy type.Comment: 8 pages, 3 figures, to be published in J. Phys. Condens. Matte
Orbital-based Scenario for Magnetic Structure of Neptunium Compounds
In order to understand a crucial role of orbital degree of freedom in the
magnetic structure of recently synthesized neptunium compounds NpTGa_5 (T=Fe,
Co, and Ni), we propose to discuss the magnetic phase of an effective
two-orbital model, which has been constructed based on a j-j coupling scheme to
explain the magnetic structure of uranium compounds UTGa_5. By analyzing the
model with the use of numerical technique such as exact diagonalization, we
obtain the phase diagram including several kinds of magnetic states. An
orbital-based scenario is discussed to understand the change in the magnetic
structure among C-, A-, and G-type antiferromagnetic phases, experimentally
observed in NpFeGa_5, NpCoGa_5, and NpNiGa_5.Comment: 18 pages, 8 figures, to appear in New Journal of Physic
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