470 research outputs found
Distinguishing genuine entangled two-photon-polarization states from independently generated pairs of entangled photons
A scheme to distinguish entangled two-photon-polarization states (ETP) from
two independent entangled one-photon-polarization states (EOP) is proposed.
Using this scheme, the experimental generation of ETP by parametric
down-conversion is confirmed through the anti-correlations between three
orthogonal two-photon-polarization states. The estimated fraction of ETP among
the correlated photon pairs is 37% in the present experimental setup.Comment: 5 pages, 2 figure
Four-photon correction in two-photon Bell experiments
Correlated photons produced by spontaneous parametric down-conversion are an
essential tool for quantum communication, especially suited for long-distance
connections. To have a reasonable count rate after all the losses in the
propagation and the filters needed to improve the coherence, it is convenient
to increase the intensity of the laser that pumps the non-linear crystal. By
doing so, however, the importance of the four-photon component of the
down-converted field increases, thus degrading the quality of two-photon
interferences. In this paper, we present an easy derivation of this nuisance
valid for any form of entanglement generated by down-conversion, followed by a
full study of the problem for time-bin entanglement. We find that the
visibility of two-photon interferences decreases as V=1-2\rho, where \rho is,
in usual situations, the probability per pulse of creating a detectable photon
pair. In particular, the decrease of V is independent of the coherence of the
four-photon term. Thanks to the fact that \rho can be measured independently of
V, the experimental verification of our prediction is provided for two
different configuration of filters.Comment: 16 pages, 4 figures; published versio
Contribution of L-type Ca2+ channels to early afterdepolarizations induced by I-Kr and I-Ks channel suppression in guinea pig ventricular myocytes
ArticleJOURNAL OF MEMBRANE BIOLOGY. 222(3): 151-166(2008)journal articl
Einstein-Podolsky-Rosen-like correlation on a coherent-state basis and inseparability of two-mode Gaussian states
The strange property of the Einstein-Podolsky-Rosen (EPR) correlation between
two remote physical systems is a primitive object on the study of quantum
entanglement. In order to understand the entanglement in canonical
continuous-variable systems, a pair of the EPR-like uncertainties is an
essential tool. Here, we consider a normalized pair of the EPR-like
uncertainties and introduce a state-overlap to a classically correlated mixture
of coherent states. The separable condition associated with this state-overlap
determines the strength of the EPR-like correlation on a coherent-state basis
in order that the state is entangled. We show that the coherent-state-based
condition is capable of detecting the class of two-mode Gaussian entangled
states. We also present an experimental measurement scheme for estimation of
the state-overlap by a heterodyne measurement and a photon detection with a
feedforward operation.Comment: 9 pages, 5 figures. A part of the materials in Sec. VI B of previous
versions was moved into another paper: Journal of Atomic, Molecular, and
Optical Physics, 2012, 854693 (2012).
http://www.hindawi.com/journals/jamop/2012/854693
Administration route-dependent vaccine efficiency of murine dendritic cells pulsed with antigens
Dendritic cells (DCs) loaded with tumour antigens have been successfully used to induce protective tumour immunity in murine models and human trials. However, it is still unclear which DC administration route elicits a superior therapeutic effect. Herein, we investigated the vaccine efficiency of DC2.4 cells, a murine dendritic cell line, pulsed with ovalbumin (OVA) in the murine E.G7-OVA tumour model after immunization via various routes. After a single vaccination using 1 × 106OVA-pulsed DC2.4 cells, tumour was completely rejected in the intradermally (i.d.; three of four mice), subcutaneously (s.c.; three of four mice), and intraperitoneally (i.p.; one of four mice) immunized groups. Double vaccinations enhanced the anti-tumour effect in all groups except the intravenous (i.v.) group, which failed to achieve complete rejection. The anti-tumour efficacy of each immunization route was correlated with the OVA-specific cytotoxic T lymphocyte (CTL) activity evaluated on day 7 post-vaccination. Furthermore, the accumulation of DC2.4 cells in the regional lymph nodes was detected only in the i.d.-and s.c.-injected groups. These results demonstrate that the administration route of antigen-loaded DCs affects the migration of DCs to lymphoid tissues and the magnitude of antigen-specific CTL response. Furthermore, the immunization route affects vaccine efficiency. © 2001 Cancer Research Campaign http://www.bjcancer.co
Empirical comparison of high gradient achievement for different metals in DC and pulsed mode
For the SwissFEL project, an advanced high gradient low emittance gun is
under development. Reliable operation with an electric field, preferably above
125 MV/m at a 4 mm gap, in the presence of an UV laser beam, has to be achieved
in a diode configuration in order to minimize the emittance dilution due to
space charge effects. In the first phase, a DC breakdown test stand was used to
test different metals with different preparation methods at voltages up to 100
kV. In addition high gradient stability tests were also carried out over
several days in order to prove reliable spark-free operation with a minimum
dark current. In the second phase, electrodes with selected materials were
installed in the 250 ns FWHM, 500 kV electron gun and tested for high gradient
breakdown and for quantum efficiency using an ultra-violet laser.Comment: 25 pages, 13 figures, 5 tables. Follow up from FEL 2008 conference
(Geyongju Korea 2008) New Title in JVST A (2010) : Vacuum breakdown limit and
quantum efficiency obtained for various technical metals using DC and pulsed
voltage source
Density of States of Disordered Two-Dimensional Crystals with Half-Filled Band
A diagrammatic method is applied to study the effects of commensurability in
two-dimensional disordered crystalline metals by using the particle-hole
symmetry with respect to the nesting vector P_0={\pm{\pi}/a, {\pi}/a} for a
half-filled electronic band. The density of electronic states (DoS) is shown to
have nontrivial quantum corrections due to both nesting and elastic impurity
scattering processes, as a result the van Hove singularity is preserved in the
center of the band. However, the energy dependence of the DoS is strongly
changed. A small offset from the middle of the band gives rise to disappearence
of quantum corrections to the DoS .Comment: to be published in Physical Review Letter
Pharmacogenetic Modulation of Orexin Neurons Alters Sleep/Wakefulness States in Mice
Hypothalamic neurons expressing neuropeptide orexins are critically involved in the control of sleep and wakefulness. Although the activity of orexin neurons is thought to be influenced by various neuronal input as well as humoral factors, the direct consequences of changes in the activity of these neurons in an intact animal are largely unknown. We therefore examined the effects of orexin neuron-specific pharmacogenetic modulation in vivo by a new method called the Designer Receptors Exclusively Activated by Designer Drugs approach (DREADD). Using this system, we successfully activated and suppressed orexin neurons as measured by Fos staining. EEG and EMG recordings suggested that excitation of orexin neurons significantly increased the amount of time spent in wakefulness and decreased both non-rapid eye movement (NREM) and rapid eye movement (REM) sleep times. Inhibition of orexin neurons decreased wakefulness time and increased NREM sleep time. These findings clearly show that changes in the activity of orexin neurons can alter the behavioral state of animals and also validate this novel approach for manipulating neuronal activity in awake, freely-moving animals
Mapping coherence in measurement via full quantum tomography of a hybrid optical detector
Quantum states and measurements exhibit wave-like --- continuous, or
particle-like --- discrete, character. Hybrid discrete-continuous photonic
systems are key to investigating fundamental quantum phenomena, generating
superpositions of macroscopic states, and form essential resources for
quantum-enhanced applications, e.g. entanglement distillation and quantum
computation, as well as highly efficient optical telecommunications. Realizing
the full potential of these hybrid systems requires quantum-optical
measurements sensitive to complementary observables such as field quadrature
amplitude and photon number. However, a thorough understanding of the practical
performance of an optical detector interpolating between these two regions is
absent. Here, we report the implementation of full quantum detector tomography,
enabling the characterization of the simultaneous wave and photon-number
sensitivities of quantum-optical detectors. This yields the largest
parametrization to-date in quantum tomography experiments, requiring the
development of novel theoretical tools. Our results reveal the role of
coherence in quantum measurements and demonstrate the tunability of hybrid
quantum-optical detectors.Comment: 7 pages, 3 figure
Generation of pressures over 40 GPa using Kawai-type multi-anvil press with tungsten carbide anvils
We have generated over 40 GPa pressures, namely, 43 and 44 GPa, at ambient temperature and 2000 K, respectively, using Kawai-type multi-anvil presses (KMAP) with tungsten carbide anvils for the first time. These high-pressure generations were achieved by combining the following pressure-generation techniques: (1) precisely aligned guide block systems, (2) high hardness of tungsten carbide, (3) tapering of second-stage anvil faces, (4) materials with high bulk modulus in a high-pressure cell, and (5) high heating efficiency
- …