Mezbahalarda kesilen ruminant karaciğerlerinden ve koyun abortuslarından izole edilen campylobacter türlerine karşı antibiyotik dirençliliği

The presence of Campylobacter spp. obtained from clinically healthy 50 sheep, goats and cattle slaughtered in slaughterhouses in Afyonkarahisar and Kutahya provinces and 44 aborted ovine fetuses obtained from the same region was investigated in this study. The subtypes were isolated by culture methods and identified by API Campy (Biomerieux, France) test kits. Campylobacter spp. was isolated from 7 samples (15.91%) out of 44 aborted ovine fetuses. After identification of Campylobacter spp., it was determined that 5 samples (71.43%) out of 7 were C. fetus subsp. fetus (71.43%) and 2 samples were C. jejuni (28.57%). Out of the 50 liver samples, Campylobacter spp. was isolated from 3 ovine livers (6%) and 1 goat liver (2%). Three of the isolates were identified as C. jejuni (75%) and 1 isolate as C. coli (25%). Campylobacter spp. was not isolated from cattle livers. Resistance rates for ciprofloxacin and tetracycline were 45.5% and 27.3% for erythromycin and 9.1% for ampicillin. No resistance was determined against gentamycin, chloramphenicol and streptomycin. The rate of susceptibility to antibiotics used was 72.7% for ampicillin, 54.5% for erythromycin, 90.9% for gentamycin, 100% for chloramphenicol, 72.7% for streptomycin and 27.3 % for ciprofloxacin and tetracycline.Bu çalışmada, Afyonkarahisar ve Kütahya illerinden mezbahalarda sağlıklı olarak kesilen koyun, keçi ve sığırlardan alınan 50’şer adet karaciğer örneği ile yine aynı bölgeden temin edilen 44 aborte koyun fetüsünde, Campylobacter spp. varlığı arandı. Kültür tekniğiyle izole edilen suşlar, API Campy (Biomerieux, France) test kitleriyle identifiye edildi. İncelenen 44 aborte koyun fetüsünden, 7 adet (%15,91) Campylobacter spp. izole edildi. İdentifikasyonları yapıldığında, örneklerin 5’inin C. fetus subsp. fetus (%71,43), 2’sinin C. jejuni (%28,57) olduğu tespit edildi. Ellişer karaciğer örneğinden, 3 koyun karaciğerinde (%6) ve 1 keçi karaciğerinde (%2) Campylobacter spp. izole edildi. İzolatların 3’ünün C. jejuni (%75), 1’inin C. coli (%25) olduğu tespit edildi. Sığır karaciğerlerinden ise Campylobacter spp. izole edilemedi. Elde edilen 11 adet Campylobacter izolatının analizinde siprofloksasin ve tetrasikline %45,5, eritromisine %27,3, ampisiline %9,1 oranında dirençlilik tespit edildi. Gentamisin, kloramfenikol ve streptomisine karşı ise dirençlilik gözlenmedi. Kullanılan antibiyotikler için tespit edilen duyarlılık oranları, ampisiline %72,7, eritromisine %54,5, gentamisine %90,9, kloramfenikole %100, streptomisine %72.7, siprofloksasin ve tetrasikline %27,3 olarak bulundu

Behaviour of a Watertight Anchored Retaining Wall in Soft Soil Conditions

A watertight prestressed anchored retaining wall was used in an excavation in Marmaris, a town located on the Southwest coast of Turkey due to presence of high water level and soft soil conditions. Following a detailed geotechnical investigation an analysis of the retaining system was performed by Plaxis Finite Element Program. The analysis consisted of stage construction simulating the real case. The behaviour of the watertight pile wall was monitored by means of inclinometric measurements. The paper describes the overall stability problems disclosed by Plaxis finite element and Slope-W slope stability programs and their remediation and the problems encountered during construction and inclinometric measurements. The lateral displacements of the retaining wall obtained in the analyses are compared with the inclinometric measurements taken during the excavation program

Para Politikası Belirsizliği Altında Aktarım Mekanizması: Türkiye Örneği

This study analyzes the transmission of monetary policy decisions to financial markets under varying levels of monetary policy uncertainty. We conducted an event study for the period June 2010-January 2015. The uncertainty regarding to monetary policy is measured by the disagreement of expectations in the CBRT Survey of Expectations. Empirical findings indicate that the effectiveness of monetary transmission mechanism is highly affected by policy uncertainty. For example, a positive policy surprise leads to an appreciation of Turkish lira against US dollar under low levels of uncertainty, whereas Turkish lira depreciates when uncertainty is high. Furthermore, an increase in the main policy rate flattens the yield curve for all uncertainty levels. On the other hand, this pattern is more pronounced while uncertainty is low and contrary to expectations, long term rates decreases after a positive policy surprise. During the periods when uncertainty regarding monetary policy is low, positive policy surprise decreases long term rates via anchoring inflation expectations

Modeling the Observed Site Response from Istanbul Strong Motion Network

An extensive site investigation study was carried out in the European side of Istanbul as part of the large-scale microzonation project for the Istanbul Metropolitan Municipality. 2912 borings mostly down to 30m depth with approximately 250m spacing were conducted within an area of 182 sqkm to investigate local site conditions. 55 stations of the Istanbul Rapid Response Network and Ataköy vertical array are located in this area. There have been few small earthquakes in the recent years with local magnitude slightly over M=4. One of these earthquakes took place on 12/3/2008 in Yalova with local magnitude of M=4.8. Vertical array stations at 4 levels (ground surface, at depths of 50m, 75m and 140m) and 23 of the 55 Istanbul Rapid Response Network stations recorded this earthquake. Based on the recorded acceleration time histories on the engineering bedrock at Ataköy vertical array, the remaining recorded acceleration time histories are modeled based on empirical site amplification relationships proposed by Borcherdt (1994) and based on a modified version of Shake91 (Idriss and Sun, 1992). An attempt is also made to model the recorded acceleration time histories during the Mw=7.4, 1999 Kocaeli Earthquake recorded at Ataköy, Fatih and Zeytinburnu stations located in the same area

Para Politikası Belirsizliği Altında Aktarım Mekanizması: Türkiye Örneği

This study analyzes the transmission of monetary policy decisions to financial markets under varying levels of monetary policy uncertainty. We conducted an event study for the period June 2010-January 2015. The uncertainty regarding to monetary policy is measured by the disagreement of expectations in the CBRT Survey of Expectations. Empirical findings indicate that the effectiveness of monetary transmission mechanism is highly affected by policy uncertainty. For example, a positive policy surprise leads to an appreciation of Turkish lira against US dollar under low levels of uncertainty, whereas Turkish lira depreciates when uncertainty is high. Furthermore, an increase in the main policy rate flattens the yield curve for all uncertainty levels. On the other hand, this pattern is more pronounced while uncertainty is low and contrary to expectations, long term rates decreases after a positive policy surprise. During the periods when uncertainty regarding monetary policy is low, positive policy surprise decreases long term rates via anchoring inflation expectations

Ultrafine conducting fibers: metallization of poly(acrylonitrile-co-glycidyl methacrylate) nanofibers

Electrospun poly(glycidylmethacrylate) (PGMA) and poly(acrylonitrile-co-glycidyl methacrylate) (P(AN-GMA)) nanofibers were coated with monodisperse silver nanoparticles by using an electroless plating technique at ambient conditions. Oxirane groups on the surface of nanofibers were replaced with reducing agent, hydrazine. Surface modified nanofibers were allowed to react with ammonia solution of AgNO3. A redox reaction takes place and metallic silver nucleate on fibers surface. Parameters affecting the particle size were determined

What Is Your Diagnosis?

DergiPark: 379011tmsj[Abstract Not Available

İzmi̇r Kalkınma Ajansı tarafından desteklenen projeleri̇n uygulama sonrası değerlendi̇rme çalışması

Araştırma, İzmir Kalkınma Ajansı (İZKA) tarafından 2009 yılında desteklenen projelerin uygulama sonrası değerlendirme çalışmasını ele almaktadır. Bu kapsamda, İZKA’dan destek alan projelerin planlama, yazım, uygulama ve uygulama sonrası aşamaları değerlendirilmiştir. Bu tebliğde, projeye konu olan boyutlardan yalnızca proje öncesi aşaması olan planlama, yazım ve değerlendirme deneyimleri ele alınmıştır. Araştırmanın örneklemi, Turizm ve Çevre Mali Destek Programı kapsamında destek almaya hak kazanan 33 projedir. Proje alan tüm kurumlarla görüşmeler gerçekleştirilerek veriler toplanmıştır. Araştırma ekibi tarafından gerçekleştirilen saha çalışmaları sonucunda, kurumların projelerle ilgili çağrıları İZKA’nın iletişim ve tanıtım çalışmaları ve kurum içi gerçekleştirilen tanıtım faaliyetleri aracılığıyla takip ettikleri ortaya çıkmıştır. Proje planlama aşamasında, kurum içi teşvik ve yönlendirme, proje fikri geliştirme, paydaşlarla işbirliği yapma, proje ekibi ve deneyimi konularının önem taşıdığı görülmektedir. Proje yazım aşamasında ise proje yazımı eğitimlerinin, İZKA desteğinin, danışman firmaların, uzman desteğinin, proje süresinin, başvuru rehberinin, İZKA bilgilendirme toplantılarının ve proje ekiplerinin önemine vurgu yapmaktadır

Evaluating the clinical significance of diazepam binding inhibitor in alzheimer's disease: A comparison with inflammatory, oxidative, and neurodegenerative biomarkers

Introduction: Alzheimer's disease (AD) is one of the pathologies that the scientific world is still desperate for. The aim of this study was the investigation of diazepam binding inhibitor (DBI) as a prognostic factor for AD prognosis. Methods: A total of 120 participants were divided into 3 groups. Forty new diagnosed Alzheimer patients (NDG) who have been diagnosed but have not started AD treatment, 40 patients who diagnosed 5 years ago (D5YG), and 40 healthy control groups (CG) were included in the study. Levels of DBI, oxidative stress, inflammatory, and neurodegenerative biomarkers were compared between 3 groups. Results: Plasma levels of DBI, oligomeric Aβ, total tau, glial fibrillary acidic protein, α-synuclein, interleukin (IL) 1β, IL6, tumor necrosis factor α, oxidative stress index, high-sensitive C-reactive protein, and DNA damage were found higher in D5YG and NDG as compared to CG (p < 0.001). On the contrary, plasma levels of total thiol, native thiol, vitamin D and vitamin B12 were lower in D5YG and NDG as compared to CG (p < 0.001). Discussion: DBI may be a potential plasma biomarker and promising drug target for AD. It could help physicians make a comprehensive evaluation with cognitive and neurodegenerative tests