Sátira e caricatura na poesia herói-cómica setecentista

[PO]O presente trabalho de investigação – com o que pretendemos optar ao título de Doutor em Línguas Modernas pela Universidade de Salamanca – versa sobre uma forma poética complexa e híbrida que, embora tenha as suas raízes na literatura clássica grega, só atingiu o momento álgido da sua produtividade no sistema de géneros muitos séculos mais tarde, concretamente, no caso da literatura portuguesa, durante o amplo movimento literário neoclássico: a poesia herói-cómica. Não foi nosso intuito prioritário, ao prosseguir esta investigação, assentar uma definição exaustiva desta forma poética, mas propormos, de um modo geral, uma descrição essencial e fundamentada, do ponto de vista poetológico, do seu funcionamento: a poesia herói-cómica, como habitualmente consigna a historiografia literária, caracteriza-se por narrar, utilizando a dicção elevada da épica, um conteúdo trivial associado a personagens e acontecimentos da sociedade coetânea do autor. A principal razão que nos levou a escolher a poesia herói-cómica como objecto deste trabalho de investigação prende-se com a consciência, e a evidência, de existir uma carência no estudo deste sub-género poético em língua portuguesa

Regional Spillovers of Transport Infrastructure Investment: A Territorial Cohesion Analysis

Territorial cohesion is a routine part of the job of spatial planners. However, it has not always been measured using a valid and solid methodology. This paper addresses conceptually how regional spillovers of transport investments of the Spanish master plan (‘‘Plan Estratégico de Infraestructuras y Transporte’’ 2005–2020) affect territorial cohesion. Different periods undergo analysis using the ‘‘extraction method’’. We calculate regional spillovers by accessibility gains measured in economic potential units (gravitational method using GDPs for each centroid under analysis). Two different typologies of regional spillovers are given, according to the direction of the effects: upstream and downstream. We conclude that the ‘Plan Estratégico’ favours territorial cohesion of Spain, but the degree of territorial cohesion produced by each region is not uniform. The end of the paper raises a number of suggestions for further research on the interaction of regional spillovers with territorial cohesion

DNA methylation in ciliates: implications in differentiation processes

Much experimental evidence on the role of DNA methylation in gene expression has been reported. Here we review reports on DNA methylation in ciliated protozoa, emphasizing its implications in cell differentiation processes. Both types of methylated bases (adenine and cytosine) can be found in macronuclear DNA. The division cycle and conjugation have been studied with regard to adenine methylation, and several different functions have been assigned to the methylation changes detected in these processes. Cytosine methylation changes were analyzed during stomatogenesis of Paramecium and encystment of Colpoda inflata. A comparative analysis with other similar microbial eukaryotic differentiation processes is carried out

The Moderating Effect of Countries' Development on the Characterization of the Social Entrepreneur: An Empirical Analysis with GEM Data

The objective of this paper is to analyze the moderating effect that the level of development of countries exerts on the factors that define the behavior of social entrepreneurs, distinguishing the effect produced in innovation-driven economies from that in factor/efficiency-driven economies. Our study contributes to the advancement of one of the most relevant problems detected in social entrepreneurship research: the lack of empirical quantitative studies, mainly due to the lack of harmonized and comparable international data. We perform an empirical multivariable analysis using 2015 Global Entrepreneurship Monitor data related to social entrepreneurship. The results show that both the variables that measure the values and skills to start a business and those related to the environment differentiate social from commercial entrepreneurs. In addition, our findings show how the development of the country plays a decisive moderating role, modifying the effect of the values and skills to be a social entrepreneur, the influence of gender, and even the relevance of entrepreneurs'perception of their environment

Heavy metal whole-cell biosensors using eukaryotic microorganisms: An updated critical review

This review analyzes the advantages and disadvantages of using eukaryotic microorganisms to design whole-cell biosensors (WCBs) for monitoring environmental heavy metal pollution in soil or aquatic habitats. Basic considerations for designing a eukaryotic WCB are also shown. A comparative analysis of the promoter genes used to design WCBs is carried out, and the sensitivity and reproducibility of the main reporter genes used is also reviewed. Three main eukaryotic taxonomic groups are considered: yeasts, microalgae, and ciliated protozoa. Models that have been widely analyzed as potential WCBs are the Saccharomyces cerevisiae model among yeasts, the Tetrahymena thermophila model for ciliates and Chlamydomonas model for microalgae. The advantages and disadvantages of each microbial group are discussed, and a ranking of sensitivity to the same type of metal pollutant from reported eukaryotic WCBs is also shown. General conclusions and possible future developments of eukaryotic WCBs are reported

Double fossilization in eukaryotic microorganisms from Lower Cretaceous amber

<p>Abstract</p> <p>Background</p> <p>Microfossils are not only useful for elucidating biological macro- and microevolution but also the biogeochemical history of our planet. Pyritization is the most important and extensive mode of preservation of animals and especially of plants. Entrapping in amber, a fossilized resin, is considered an alternative mode of biological preservation. For the first time, the internal organization of 114-million-year-old microfossils entrapped in Lower Cretaceous amber is described and analyzed, using adapted scanning electron microscopy in backscattered electron mode in association with energy dispersive X-ray spectroscopy microanalysis. Double fossilization of several protists included in diverse taxonomical groups and some vegetal debris is described and analyzed.</p> <p>Results</p> <p>In protists without an exoskeleton or shell (ciliates, naked amoebae, flagellates), determinate structures, including the nuclei, surface envelopes (cortex or cytoplasmic membrane) and hyaloplasm are the main sites of pyritization. In protists with a biomineralized skeleton (diatoms), silicon was replaced by pyrite. Permineralization was the main mode of pyritization. Framboidal, subhedral and microcrystalline are the predominant pyrite textures detected in the cells. Abundant pyritized vegetal debris have also been found inside the amber nuggets and the surrounding sediments. This vegetal debris usually contained numerous pyrite framboids and very densely packed polycrystalline pyrite formations infilled with different elements of the secondary xylem.</p> <p>Conclusion</p> <p>Embedding in amber and pyritization are not always alternative modes of biological preservation during geological times, but double fossilization is possible under certain environmental conditions. Pyritization in protists shows a quite different pattern with regard to plants, due to the different composition and cellular architecture in these microorganisms and organisms. Anaerobic sulphate-reducing bacteria could play a crucial role in this microbial fossilization.</p

Effect of long-chain fatty alcohols from orujo olive oil on nitric oxide and eicosanoid generation

1st International Immunonutrition Workshop, Valencia, 3–5 October 2007, Valencia, SpainOlive pomace oil (‘orujo’ oil) is an olive oil product suitable for human consumption that is traditionally produced in Spain(1). The non-acylglycerol component of this oil is a good source of interesting minor components, e.g. triterpenes(2), or fatty alcohols, derived from waxy materials.This study is part of the project AGL2005–00572/ALI, financially supported by the Comision Interministerial de Ciencia y Tecnologia (CICYT).Peer reviewe

Nonprofit good governance mechanisms: A systematic literature review

There is widespread acknowledgment of the importance of nonprofit good governance with a need for guidance on different effective mechanisms to increase ethical practices for the whole sector to assist professionals and researchers. This study explores two research questions: (1) What are the main reasons that inspire nonprofit organizations (NPOs) to implement good governance mechanisms? (2) What are the good governance mechanisms conducted by NPOs? The purpose is to serve as a reference and an instrument of reflection for interested NPOs exploring good governance mechanisms to make their accountability work more effective. We used a systematic literature review methodology for identification, selection, and analysis of published research on nonprofit good governance. A set of 89 articles published until 2021 was analyzed, and a new classification that identified 3 lines and 13 sublines of research was provided. Our results show that a variety of internal mechanisms and international third-party initiatives are underpinned by the need to adhere to standards of ethics and honesty.Grupo de Investigación “SEJ289: Information and Management Systems in the Andalusian Company” de la Universidad de Jaé

Nucleotide sequence and transfer properties of two novel types of Actinobacillus pleuropneumoniae plasmids carrying the tetracycline resistance gene tet(H)

17 p.The aim of this study is to analyze the sequence and transfer properties of two tetracycline resistance plasmids found in clinical isolates of Actinobacillus pleuropneumoniae in order to assert their role in the spread of tetracycline resistenceS

Antimicrobial susceptibility patterns of Haemophilus parasuis from pigs in the United Kingdom and Spain

18 p.A total of 30 British and 30 Spanish Haemophilus parasuis isolates were tested for their susceptibility to 19 of the antimicrobials currently used in swine practice with a broth microdilution method in order to know the emergence of resistance against these compounds in this porcine pathogen. All the British isolates were susceptible to penicillin, ceftiofur, erythromycin, tilmicosin, enrofloxacin, and florfenicol, and most of them were susceptible to the remaining antimicrobials (the highest resistance rate found was of 20% to neomycin). In contrast, all the Spanish isolates were susceptible exclusively to florfenicol, and high proportions of resistance were encountered for penicillin, ampicillin, oxytetracycline, erythromycin, tilmicosin, tiamulin and trimethoprim + sulphamethoxazole; in addition, a bimodal or multimodal distribution, or tailing of Spanish isolates over the MIC range was observed for clindamycin, sulphonamides and tylosine tartrate, suggesting the development of acquired resistance. In addition, several multiresistance patterns were found among the Spanish isolates, 23.3% of them being resistant to at least eight antimicrobials, the same rate as that encountered for those being susceptible to all antimicrobials tested. This study showed that in general British H. parasuis isolates are susceptible to antimicrobial agents routinely used for treatment of porcine respiratory diseases; however, the Spanish isolates need a more continuous surveillance of their susceptibility patternsS