25 research outputs found
DE QUE EDUCAÇAO NECESSITAMOS? Por uma educação pública e contra-hegemônica
Este artigo propõe um diálogo entre especificidades da Formação de Professores, sob a Ăłtica do PARFOR, e a proposta, encampada pelo governo federal, pela regulamentação da Educação Domiciliar. Busca-se compreender as relações entre o projeto governamental e seus impactos no espaço macro e micro da Educação brasileira. Partimos dos textos apresentados na JOINPP 2019, na mesa temática “De que educação necessitamos?”, que problematizaram o desmonte das polĂticas educacionais marcado pela deslegitimação das conquistas histĂłricas dos trabalhadores, perda de direitos e desconstrução da educação pĂşblica. Este texto articula as reflexões sobre o PARFOR, como polĂtica nacional de formação de professores, suas correlações formativas para a ação/trajetĂłria de mulheres-professoras, suas práticas de letramento escolar e o projeto neoliberal de privatização e desfinanciamento da educação pĂşblica
Health-related quality of life in patients with type 1 diabetes mellitus in the different geographical regions of Brazil : data from the Brazilian Type 1 Diabetes Study Group
Background: In type 1 diabetes mellitus (T1DM) management, enhancing health-related quality of life (HRQoL) is as important as good metabolic control and prevention of secondary complications. This study aims to evaluate possible regional differences in HRQoL, demographic features and clinical characteristics of patients with T1DM in Brazil, a country of continental proportions, as well as investigate which variables could influence the HRQoL of these individuals and contribute to these regional disparities. Methods: This was a retrospective, cross-sectional, multicenter study performed by the Brazilian Type 1 Diabetes Study Group (BrazDiab1SG), by analyzing EuroQol scores from 3005 participants with T1DM, in 28 public clinics, among all geographical regions of Brazil. Data on demography, economic status, chronic complications, glycemic control and lipid profile were also collected. Results: We have found that the North-Northeast region presents a higher index in the assessment of the overall health status (EQ-VAS) compared to the Southeast (74.6 ± 30 and 70.4 ± 19, respectively; p < 0.05). In addition, North- Northeast presented a lower frequency of self-reported anxiety-depression compared to all regions of the country (North-Northeast: 1.53 ± 0.6; Southeast: 1.65 ± 0.7; South: 1.72 ± 0.7; Midwest: 1.67 ± 0.7; p < 0.05). These findings could not be entirely explained by the HbA1c levels or the other variables examined. Conclusions: Our study points to the existence of additional factors not yet evaluated that could be determinant in the HRQoL of people with T1DM and contribute to these regional disparities
Análise da eficácia do uso terapĂŞutico da trimetazidina nas principais sĂndromes coronarianas agudas
A injĂşria de reperfusĂŁo, ou isquemia, Ă© um mecanismo fisiopatolĂłgico que ocorre nas etiopatogenias do miocárdio, como na angina instável. Assim, sĂŁo utilizados fármacos adjuvantes citoprotetores, como a trimetazidina (TMZ), que visam Ă diminuição do tempo de hospitalização e melhora na função cardĂaca com ação profilática contra essa lesĂŁo. No entanto, apesar dos seus potenciais benefĂcios no tratamento da sĂndrome coronariana aguda, ainda nĂŁo está clara a sua eficácia em relação a outras terapias disponĂveis. Nesse sentido, o objetivo do estudo Ă© analisar a eficácia do uso terapĂŞutico da trimetazidina nas principais sĂndromes coronarianas agudas. Foi realizada uma revisĂŁo sistemática usando as bases de dados PubMed, Cochrane Library e Embase. Um total de 3 estudos foi incluĂdo na análise. Os resultados mostraram que a terapia com trimetazidina reduziu significativamente a incidĂŞncia de eventos cardĂacos adversos maiores (ECAM) (OR = 0,33, IC 95% 0,15-0,75, p = 0,007), menor dano miocárdico (p < 0,05) e fração de ejeção ventricular esquerda mais elevada e menos eventos adversos em comparação com o grupo placebo (p < 0,05). NĂŁo foram observadas diferenças significativas entre os grupos de trimetazidina e controle em termos de mortalidade por todas as causas, mortalidade cardiovascular ou incidĂŞncia de eventos adversos. Os resultados deste estudo sugerem que a terapia adjuvante com trimetazidina pode melhorar os resultados clĂnicos e a função cardĂaca em pacientes com IAM sem aumentar o risco de eventos adversos. No entanto, sĂŁo necessários mais ensaios clĂnicos randomizados em larga escala para confirmar esses resultados e determinar a duração e dose ideais da terapia com trimetazidina nessa população de pacientes
Pervasive gaps in Amazonian ecological research
Biodiversity loss is one of the main challenges of our time,1,2 and attempts to address it require a clear un derstanding of how ecological communities respond to environmental change across time and space.3,4
While the increasing availability of global databases on ecological communities has advanced our knowledge
of biodiversity sensitivity to environmental changes,5–7 vast areas of the tropics remain understudied.8–11 In
the American tropics, Amazonia stands out as the world’s most diverse rainforest and the primary source of
Neotropical biodiversity,12 but it remains among the least known forests in America and is often underrepre sented in biodiversity databases.13–15 To worsen this situation, human-induced modifications16,17 may elim inate pieces of the Amazon’s biodiversity puzzle before we can use them to understand how ecological com munities are responding. To increase generalization and applicability of biodiversity knowledge,18,19 it is thus
crucial to reduce biases in ecological research, particularly in regions projected to face the most pronounced
environmental changes. We integrate ecological community metadata of 7,694 sampling sites for multiple or ganism groups in a machine learning model framework to map the research probability across the Brazilian
Amazonia, while identifying the region’s vulnerability to environmental change. 15%–18% of the most ne glected areas in ecological research are expected to experience severe climate or land use changes by
2050. This means that unless we take immediate action, we will not be able to establish their current status,
much less monitor how it is changing and what is being lostinfo:eu-repo/semantics/publishedVersio
Pervasive gaps in Amazonian ecological research
Biodiversity loss is one of the main challenges of our time,1,2 and attempts to address it require a clear understanding of how ecological communities respond to environmental change across time and space.3,4 While the increasing availability of global databases on ecological communities has advanced our knowledge of biodiversity sensitivity to environmental changes,5,6,7 vast areas of the tropics remain understudied.8,9,10,11 In the American tropics, Amazonia stands out as the world's most diverse rainforest and the primary source of Neotropical biodiversity,12 but it remains among the least known forests in America and is often underrepresented in biodiversity databases.13,14,15 To worsen this situation, human-induced modifications16,17 may eliminate pieces of the Amazon's biodiversity puzzle before we can use them to understand how ecological communities are responding. To increase generalization and applicability of biodiversity knowledge,18,19 it is thus crucial to reduce biases in ecological research, particularly in regions projected to face the most pronounced environmental changes. We integrate ecological community metadata of 7,694 sampling sites for multiple organism groups in a machine learning model framework to map the research probability across the Brazilian Amazonia, while identifying the region's vulnerability to environmental change. 15%–18% of the most neglected areas in ecological research are expected to experience severe climate or land use changes by 2050. This means that unless we take immediate action, we will not be able to establish their current status, much less monitor how it is changing and what is being lost