661 research outputs found
Search for Anomalous Couplings in Top Decay at Hadron Colliders
We present a quantitative study on sensitivities to the top-decay anomalous
couplings, taking into account realistic experimental conditions expected at
Tevatron and LHC. A double angular distribution of W and charged lepton in the
top decay is analyzed, using ttbar events in the lepton+jets channel. In order
to improve sensitivities to the anomalous couplings, we apply two techniques:
(1) We use a likelihood fitting method for full kinematical reconstruction of
each top event. (2) We develop a new effective spin reconstruction method for
leptonically-decayed top quarks; this method does not require spin information
of the antitop side. For simplicity, we neglect couplings of right-handed
bottom quark as well as CP violating couplings. The 95% C.L. estimated bound on
a ratio of anomalous couplings reads -0.81 < f_2/f_1 < -0.70,
-0.12<f_2/f_1<0.14 using 1000 reconstructed top events at Tevatron, while
-0.74<f_2/f_1<-0.72, -0.01<f_2/f_1<0.01 is expected with 100k reconstructed top
events at LHC, where only statistical errors are taken into account. A two-fold
ambiguity in the allowed range remains when the number of events exceeds a few
hundred.Comment: 21 pages, 15 figure
Measuring Anomalous Couplings in H->WW* Decays at the International Linear Collider
Measurement of the Higgs coupling to W-bosons is an important test of our
understanding of the electroweak symmetry breaking mechanism. We study the
sensitivity of the International Linear Collider (ILC) to the presence of
anomalous HW+W- couplings using ZH -> nu nu WW* -> nu nu 4j events. Using an
effective Lagrangian approach, we calculate the differential decay rates of the
Higgs boson including the effects of new dimension-5 operators. We present a
Monte Carlo simulation of events at the ILC, using a full detector simulation
based on geant4 and a real event reconstruction chain. Expected constraints on
the anomalous couplings are given.Comment: 18 pages, 7 figures, 1 tabl
A Start-Timing Detector for the Collider Experiment PHENIX at RHIC-BNL
We describe a start-timing detector for the PHENIX experiment at the
relativistic heavy-ion collider RHIC. The role of the detector is to detect a
nuclear collision, provide precise time information with an accuracy of 50ps,
and determine the collision point along the beam direction with a resolution of
a few cm. Technical challenges are that the detector must be operational in a
wide particle-multiplicity range in a high radiation environment and a strong
magnetic field. We present the performance of the prototype and discuss the
final design of the detector.Comment: 12 pages, LaTeX, 9 gif and 4 ps figures. Submitted to NIM
Measurement of the electron transmission rate of the gating foil for the TPC of the ILC experiment
We have developed a gating foil for the time projection chamber envisaged as
a central tracker for the international linear collider experiment. It has a
structure similar to the Gas Electron Multiplier (GEM) with a higher optical
aperture ratio and functions as an ion gate without gas amplification. The
transmission rate for electrons was measured in a counting mode for a wide
range of the voltages applied across the foil using an Fe source and a
laser in the absence of a magnetic field. The blocking power of the foil
against positive ions was estimated from the electron transmissions.Comment: 25 pages containing 14 figures and 1 tabl
Cosmic ray tests of a GEM-based TPC prototype operated in Ar-CF4-isobutane gas mixtures
Argon with an admixture of CF4 is expected to be a good candidate for the gas
mixture to be used for a time projection chamber (TPC) in the future linear
collider experiment because of its small transverse diffusion of drift
electrons especially under a strong magnetic field. In order to confirm the
superiority of this gas mixture over conventional TPC gases we carried out
cosmic ray tests using a GEM-based TPC operated mostly in Ar-CF4-isobutane
mixtures under 0 - 1 T axial magnetic fields. The measured gas properties such
as gas gain and transverse diffusion constant as well as the observed spatial
resolution are presented.Comment: 22 pages, 18 figures. Published in Nuclear Instruments and Methods in
Physics Research A. Fig. 3 in the introduction was corrected since it had not
been properly normalized. Minor corrections and no changes in the conclusio
Serum midkine levels are increased in patients with various types of carcinomas
The level of expression of midkine (MK), a heparin-binding growth factor, is increased in many types of human carcinomas. An enzyme-linked immunoassay, which utilizes a combination of rabbit and chicken antibodies revealed that serum MK level in the controls (n= 135) was 0.154 ± 0.076 (mean ± SD) ng ml–1with an apparent cut-off value as 0.5 ng ml–1. Serum MK level was significantly elevated in the cancer patients (n= 150) (P< 0.001); 87% of the patients showed levels of more than 0.5 ng ml–1. All ten types of cancer examined showed a similar profile of serum MK level. There was no or weak correlation between C-reactive protein level, a marker of inflammation, and serum MK level. Furthermore, in case of gastric carcinoma and lung carcinoma, patients with stage I carcinoma already showed elevated serum MK levels. The present results indicated that serum MK could serve as a general tumour marker with a good potential for clinical application. © 2000 Cancer Research Campaig
The proangiogenic capacity of polymorphonuclear neutrophils delineated by microarray technique and by measurement of neovascularization in wounded skin of CD18-deficient mice
Growing evidence supports the concept that polymorphonuclear neutrophils (PMN) are critically involved in inflammation-mediated angiogenesis which is important for wound healing and repair. We employed an oligonucleotide microarray technique to gain further insight into the molecular mechanisms underlying the proangiogenic potential of human PMN. In addition to 18 known angiogenesis-relevant genes, we detected the expression of 10 novel genes, namely midkine, erb-B2, ets-1, transforming growth factor receptor-beta(2) and -beta(3), thrombospondin, tissue inhibitor of metalloproteinase 2, ephrin A2, ephrin B2 and restin in human PMN freshly isolated from the circulation. Gene expression was confi rmed by the RT-PCR technique. In vivo evidence for the role of PMN in neovascularization was provided by studying neovascularization in a skin model of wound healing using CD18-deficient mice which lack PMN infi ltration to sites of lesion. In CD18-deficient animals, neo- vascularization was found to be signifi cantly compromised when compared with wild- type control animals which showed profound neovascularization within the granulation tissue during the wound healing process. Thus, PMN infiltration seems to facilitate inflammation mediated angiogenesis which may be a consequence of the broad spectrum of proangiogenic factors expressed by these cells. Copyright (c) 2006 S. Karger AG, Basel
Event Reconstruction in the PHENIX Central Arm Spectrometers
The central arm spectrometers for the PHENIX experiment at the Relativistic
Heavy Ion Collider have been designed for the optimization of particle
identification in relativistic heavy ion collisions. The spectrometers present
a challenging environment for event reconstruction due to a very high track
multiplicity in a complicated, focusing, magnetic field. In order to meet this
challenge, nine distinct detector types are integrated for charged particle
tracking, momentum reconstruction, and particle identification. The techniques
which have been developed for the task of event reconstruction are described.Comment: Accepted for publication in Nucl. Instrum. A. 34 pages, 23 figure
Digital Autopsy: Popular Tools for an Unpopular Procedure
Digital autopsy is the future of postmortem examination of the human body through digital visualization. Imaging modalities such as CT scanners and MRI scanners use X rays and magnetic fields to visualize the structures within the human body. The outputs from these modalities are obtained in a DICOM (Digital Imaging and Communications of Medicine) format. They are in gray-scale consisting of information in every slice taken during the scan. This is rendered and visualized as the full body in a digital format during the digital autopsy procedure. The visualization rendering produces a three-dimensional body, further presented in colour format based on each structure of the human organ system. Digital autopsy is a technology which allows pathologists to navigate and explore deeper into the human body. It allows analysis to be done in both two-dimensional and three dimensional perspectives. Digital autopsy involves analysis of human pathology and anatomical findings for diagnostic purposes. It can also be used for education and research purposes. Another advantage of digital autopsy is the availability of information and data that can be easily and securely transferred to a different digital autopsy facility at a different location. Thus, digital autopsy provides an efficient, fast, cheaper and accurate post-mortem data enabling a forensic pathologists to play a more effective role in the criminal justice system
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