A RoundD-like Roundabout Scenario in CARLA Simulator

Evaluating the challenges and opportunities of cooperative autonomous vehicles (CAV) require an adapted simulation methodology reproducing realistic driving and sensory contexts. In this paper, we propose a RounD-like CARLA scenario reproducing in CARLA the driving context recorded in the RounD dataset. We focus in particular on roundabout scenarios, as they are considered particularly challenging for CAV. We present the methodology followed to generate the CARLA scenario and describe challenges to reproduce trajectories corresponding to RounD. Origin and destination of vehicles, waypoint and speed are extracted from RounD for CARLA vehicles to closely reproduce the driving patterns observed in RounD. The benefit of such scenario are manyfold, such as evaluating control algorithms of CAVs, deep AI reinforcement learning, or vehicular sensor data sampling under realistic driving contexts. It notably will reduce the gap of AI mechanisms for CAV between simulation scenarios and realistic conditions

A low density of 0.8 g/cc for the Trojan binary asteroid 617 Patroclus

The Trojan population consists of two swarms of asteroids following the same orbit as Jupiter and located at the L4 and L5 Lagrange points of the Jupiter-Sun system (leading and following Jupiter by 60 degrees). The asteroid 617 Patroclus is the only known binary Trojan (Merline et al. 2001). The orbit of this double system was hitherto unknown. Here we report that the components, separated by 680 km, move around the system centre of mass, describing roughly a circular orbit. Using the orbital parameters, combined with thermal measurements to estimate the size of the components, we derive a very low density of 0.8 g/cc. The components of Patroclus are therefore very porous or composed mostly of water ice, suggesting that they could have been formed in the outer part of the solar system.Comment: 10 pages, 3 figures, 1 tabl

Rabies, Still Neglected after 125 Years of Vaccination

International audienceno abstrac

Genetic polymorphisms of MMP1, MMP3 and MMP7 gene promoter and risk of colorectal adenoma

BACKGROUND: Matrix metalloproteinases (MMP) have been shown to play a role in colorectal cancer (CRC). More recently, MMP1, MMP3 and MMP7 functional gene promoter polymorphisms have been found to be associated with CRC occurrence and prognosis. To document the role of MMP polymorphisms in the early step of colorectal carcinogenesis, we investigated their association with colorectal adenoma risk in a case-control study comprising 295 patients with large adenomas (LA), 302 patients with small adenomas (SA) and 568 polyp-free (PF) controls. METHODS: Patients were genotyped using automated fragment analysis for MMP1 -1607 ins/del G and MMP3 -1612 ins/delA (MMP3.1) polymorphisms and allelic discrimination assay for MMP3 -709 A/G (MMP3.2) and MMP7 -181 A/G polymorphisms. Association between MMP genotypes and colorectal adenomas was first tested for each polymorphism separately and then for combined genotypes using the combination test. Adjustment on relevant variables and estimation of odds ratios were performed using unconditional logistic regression. RESULTS: No association was observed between the polymorphisms and LA when compared to PF or SA. When comparing SA to PF controls, analysis revealed a significant association between MMP3 -1612 ins/delA polymorphism and SA with an increased risk associated with the 6A/6A genotype (OR = 1.67, 95%CI: 1.20–2.34). Using the combination test, the best association was found for MMP3.1-MMP1 (p = 0.001) with an OR of 1.88 (95%CI: 1.08–3.28) for the combined genotype 2G/2G-6A/6A estimated by logistic regression. CONCLUSION: These data show a relation between MMP1 -1607 ins/del G and MMP3 -1612 ins/delA combined polymorphisms and risk of SA, suggesting their potential role in the early steps of colorectal carcinogenesis

Brexit : quelles conséquences agricoles et halieutiques ?

Brexit: What Consequences for Agriculture and Fisheries? After the Brexit referendum in 2016, the management of the exit of the United Kingdom (UK) from the European Union (EU) has become a real political crisis with multiple consequences. With uncertainty as a keyword, this subject has placed the agricultural and fisheries sector at the centre of several issues. This exceptional political situation has given rise to doubt on the agro-food market, both in the UK and in the twenty-seven members states. With regards to the sea sector, Brexit is revealing structural issues for the fisheries industry at continent-wide level. The path that the exit of the UK will take will determine the future of fish production in many countries and urge London to rethink its food supply that will have to follow new modalities

Enquête sanitaire sur les conditions d'élevage de veaux laitiers Holstein destinés à un programme d'amélioration génétique

TOULOUSE3-BU Santé-Centrale (315552105) / SudocTOULOUSE-EN Vétérinaire (315552301) / SudocSudocFranceF

Brexit : quelles conséquences agricoles et halieutiques ?

Brexit: What Consequences for Agriculture and Fisheries? After the Brexit referendum in 2016, the management of the exit of the United Kingdom (UK) from the European Union (EU) has become a real political crisis with multiple consequences. With uncertainty as a keyword, this subject has placed the agricultural and fisheries sector at the centre of several issues. This exceptional political situation has given rise to doubt on the agro-food market, both in the UK and in the twenty-seven members states. With regards to the sea sector, Brexit is revealing structural issues for the fisheries industry at continent-wide level. The path that the exit of the UK will take will determine the future of fish production in many countries and urge London to rethink its food supply that will have to follow new modalities

Portabilité, réemploi et transposition des modèles d'interaction homme-machine (implications de la gestion des contextes humains pour les architectures logicielles)

La conception de l'interaction homme-machine est devenue un enjeu majeur dans l'industrie dans le cadre du développement de systèmes informatiques complexes. Il ne s'agit plus seulement de concevoir un système au-dessus duquel sont proposées des interfaces graphiques, mais de concevoir un système d'interaction homme-machine intégré dans lequel l'utilisateur possède une compréhension effective du modèle applicatif sous jacent tout en ayant à sa disposition des moyens d'interaction adaptés à son contexte opérationnel. Cette thèse propose un modèle de conception des interactions homme-machine pour l'industrie logicielle basée sur le paradigme HIC qui reprend une vision fonctionnelle de l'interaction et propose une séparation des préoccupations entre présentation, interaction et application. Poursuivant sur cette voie, la conception des interfaces homme-machine appliquée au domaine du génie logiciel a donné lieu dans un premier temps à l'implémentation d'une architecture composée d'un middleware d'interaction et d'un conteneur d'interaction homme-machine. Puis cette approche, inspirée des processus d'industrialisation du développement logiciel a été généralisée au sein d'un atelier de prototypage et de conception, JAGUAR. Enfin, nous montrons comment l'adoption de cette vision fonctionnelle de l'interaction homme-machine ainsi que l'intégration des modèles de conception proposés ont permis aux développeurs de systèmes interactifs d'accroître l'adéquation entre les besoins humains et des capacités des systèmes d'informations.The design of human-computer interaction is a major step for the industry today when one wants to develop complex information systems. The task is not only to design a new system on top of which some graphic interface are provided to the users, but to build an interactive system for which the user can understand the underlying application model and also for which the interaction means are adequate for the operational task. In this thesis, we propose a model to design human-computer interaction for the software industry, based on the HIC paradigm, built on a functional view of the interaction to propose a relevant separation of concerns between presentation, interaction and application. Going further on this path, the design of human-computer interfaces is applied to the software engineering process, and we propose to implement a new type of platform for this task. We decided to build two modules as a first experiment of our approach: Interaction Middleware and Interaction Container. Then, the separation of concerns is implemented, tested and generalized with the support of a software modelling and prototyping framework, named JAGUAR. Finally, we show how the adoption of this functional vision of the interaction model design and the integration of those models enables the designers and developers of interactive systems to increase the relevance of the actual user needs with the information systems capabilities.ORSAY-PARIS 11-BU Sciences (914712101) / SudocSudocFranceF

A RoundD-like Roundabout Scenario in CARLA Simulator

Evaluating the challenges and opportunities of cooperative autonomous vehicles (CAV) require an adapted simulation methodology reproducing realistic driving and sensory contexts. In this paper, we propose a RounD-like CARLA scenario reproducing in CARLA the driving context recorded in the RounD dataset. We focus in particular on roundabout scenarios, as they are considered particularly challenging for CAV. We present the methodology followed to generate the CARLA scenario and describe challenges to reproduce trajectories corresponding to RounD. Origin and destination of vehicles, waypoint and speed are extracted from RounD for CARLA vehicles to closely reproduce the driving patterns observed in RounD. The benefit of such scenario are manyfold, such as evaluating control algorithms of CAVs, deep AI reinforcement learning, or vehicular sensor data sampling under realistic driving contexts. It notably will reduce the gap of AI mechanisms for CAV between simulation scenarios and realistic conditions

A RoundD-like Roundabout Scenario in CARLA Simulator

Evaluating the challenges and opportunities of cooperative autonomous vehicles (CAV) require an adapted simulation methodology reproducing realistic driving and sensory contexts. In this paper, we propose a RounD-like CARLA scenario reproducing in CARLA the driving context recorded in the RounD dataset. We focus in particular on roundabout scenarios, as they are considered particularly challenging for CAV. We present the methodology followed to generate the CARLA scenario and describe challenges to reproduce trajectories corresponding to RounD. Origin and destination of vehicles, waypoint and speed are extracted from RounD for CARLA vehicles to closely reproduce the driving patterns observed in RounD. The benefit of such scenario are manyfold, such as evaluating control algorithms of CAVs, deep AI reinforcement learning, or vehicular sensor data sampling under realistic driving contexts. It notably will reduce the gap of AI mechanisms for CAV between simulation scenarios and realistic conditions