10,237 research outputs found

    Catholic Institutions and Justice Obligations

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    To what extent would the poorest consumers nutritionally and socially benefit from a global food tax and subsidy reform ? A framed field experiment based on daily food intake

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    In this paper we propose a new method in experimental economics, designed to evaluate the effectiveness of public policy incentives aimed at altering consumer behaviors. We apply this method to wide-ranging policies on food prices, which use subsidies to increase the consumption of healthy products and taxes to reduce that of unhealthy ones. Our protocol allows for observation of an individual’s daily food consumption before and after the policy. We examine two separate policies: the one subsidizes fruit and vegetables, while the other one combines taxes and subsidies. We measure their nutritional and economic impacts on the choices of low-income French consumers, compared to a reference group. Both policies have a positive effect on the nutritional quality of food choices of the two groups but initial gaps widen, especially with the subsidies. In the low-income group this can be explained by an initially unfavorable pattern and by weaker price elasticities. The redistributive effects are therefore doubly regressive. Moreover, the individual price elasticities, that the experimental approach enables us to measure, show widely diverse behaviors. They are counter-effective for close to 40% of our sample of poor women.OBESITY;PUBLIC POLICY;SOCIAL INEQUALITIES;POVERTY;INCOME REDISTRIBUTION;REGRESSIVE TAX;INDIVIDUALIZED PRICE INDEX;NUTRITIONAL TAX SYSTEM;FOOD TAX

    A frequency-adjustable electromagnet for hyperthermia measurements on magnetic nanoparticles

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    We describe a low-cost and simple setup for hyperthermia measurements on colloidal solutions of magnetic nanoparticles (ferrofluids) with a frequency-adjustable magnetic field in the range 5-500 kHz produced by an electromagnet. By optimizing the general conception and each component (nature of the wires, design of the electromagnet), a highly efficient setup is obtained. For instance, in a useful gap of 1.1 cm, a magnetic field of 4.8 mT is generated at 100 kHz and 500 kHz with an output power of 3.4 W and 75 W, respectively. A maximum magnetic field of 30 mT is obtained at 100 kHz. The temperature of the colloidal solution is measured using optical fiber sensors. To remove contributions due to heating of the electromagnet, a differential measurement is used. In this configuration the sensitivity is better than 1.5 mW at 100 kHz and 19.3 mT. This setup allows one to measure weak heating powers on highly diluted colloidal solutions. The hyperthermia characteristics of a solution of Fe nanoparticles are described, where both the magnetic field and the frequency dependence of heating power have been measured

    High Dimensional Classification with combined Adaptive Sparse PLS and Logistic Regression

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    Motivation: The high dimensionality of genomic data calls for the development of specific classification methodologies, especially to prevent over-optimistic predictions. This challenge can be tackled by compression and variable selection, which combined constitute a powerful framework for classification, as well as data visualization and interpretation. However, current proposed combinations lead to instable and non convergent methods due to inappropriate computational frameworks. We hereby propose a stable and convergent approach for classification in high dimensional based on sparse Partial Least Squares (sparse PLS). Results: We start by proposing a new solution for the sparse PLS problem that is based on proximal operators for the case of univariate responses. Then we develop an adaptive version of the sparse PLS for classification, which combines iterative optimization of logistic regression and sparse PLS to ensure convergence and stability. Our results are confirmed on synthetic and experimental data. In particular we show how crucial convergence and stability can be when cross-validation is involved for calibration purposes. Using gene expression data we explore the prediction of breast cancer relapse. We also propose a multicategorial version of our method on the prediction of cell-types based on single-cell expression data. Availability: Our approach is implemented in the plsgenomics R-package.Comment: 9 pages, 3 figures, 4 tables + Supplementary Materials 8 pages, 3 figures, 10 table

    Désaisonnalisation des agrégats monétaires : Mise en place d’une chaîne rénovée.

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    The analysis of seasonality in economics and the development of new seasonal adjustment procedures have been following new directions in the last twenty years. We study this question through the work performed at the Banque de France (Monetary Statistic and Studies Directorate) to compile new seasonally adjusted (SA) data. A brief discussion of the academic literature show the necessity to complement the existing software with empirical rules fixed by the practitioner in order to make all the methodological choices clear, thus avoiding any ambiguity. In the implementation of the new production process, we focus on the revision policy of some keys parameters of the whole process in order to minimize the subsequent revisions in the publication of SA data. We illustrate this new methodology with SA series relating to monetary aggregates, including loans to enterprises and to households, and provide a detailed analysis of the consistency between flows and outstanding amount SA figures, an issue particularly relevant for monetary an financial data.Seasonal Adjustment Methods ; Monetary Aggregates ; Outliers ; SARIMA Models ; Spectral Analysis.

    Description of Pairing correlation in Many-Body finite systems with density functional theory

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    Different steps leading to the new functional for pairing based on natural orbitals and occupancies proposed in ref. [D. Lacroix and G. Hupin, arXiv:1003.2860] are carefully analyzed. Properties of quasi-particle states projected onto good particle number are first reviewed. These properties are used (i) to prove the existence of such a functional (ii) to provide an explicit functional through a 1/N expansion starting from the BCS approach (iii) to give a compact form of the functional summing up all orders in the expansion. The functional is benchmarked in the case of the picked fence pairing Hamiltonian where even and odd systems, using blocking technique are studied, at various particle number and coupling strength, with uniform and random single-particle level spacing. In all cases, a very good agreement is found with a deviation inferior to 1% compared to the exact energy.Comment: 14 pages, 9 figure

    Stochastic dynamics of microcavity polaritons

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    We study the time dependent polariton condensation as well as the parametric scattering process of polaritons in a semiconductor microcavity. Based upon a new stochastic scheme the dynamics for both cases is fully analyzed. We show how the evolution of the system is described by a set of stochastic differential Schrodinger equations which in average reproduces the exact dynamics. Furthermore, we underline the role that Coulomb correlations plays in the polariton dynamics. Threshold behaviors are well captured by the present approach. The results are in complete agreement with recent experimental observations.Comment: 6 pages, 8 figures. To appear in Solid State Communication

    Surface induced magnetization reversal of MnP nanoclusters embedded in GaP

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    We investigate the quasi-static magnetic behavior of ensembles of non-interacting ferromagnetic nanoparticles consisting of MnP nanoclusters embedded in GaP(001) epilayers grown at 600, 650 and 700{\deg}C. We use a phenomenological model, in which surface effects are included, to reproduce the experimental hysteresis curves measured as a function of temperature (120-260 K) and direction of the applied field. The slope of the hysteresis curve during magnetization reversal is determined by the MnP nanoclusters size distribution, which is a function of the growth temperature. Our results show that the coercive field is very sensitive to the strength of the surface anisotropy, which reduces the energy barrier between the two states of opposite magnetization. Notably, this reduction in the energy barrier increases by a factor of 3 as the sample temperature is lowered from 260 to 120 K.Comment: 7 pages, 5 figure

    Quadruplexes In ‘Dicty’: Crystal Structure Of A Four-Quartet G-Quadruplex Formed By G-Rich Motif Found In The Dictyostelium Discoideum Genome

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    Guanine-rich DNA has the potential to fold into non-canonical G-quadruplex (G4) structures. Analysis of the genome of the social amoeba Dictyostelium discoideum indicates a low number of sequences with G4-forming potential (249–1055). Therefore, D. discoideum is a perfect model organism to investigate the relationship between the presence of G4s and their biological functions. As a first step in this investigation, we crystallized the dGGGGGAGGGGTACAGGGGTACAGGGG sequence from the putative promoter region of two divergent genes in D. discoideum. According to the crystal structure, this sequence folds into a four-quartet intramolecular antiparallel G4 with two lateral and one diagonal loops. The G-quadruplex core is further stabilized by a G-C Watson–Crick base pair and a A–T–A triad and displays high thermal stability (Tm \u3e 90°C at 100 mM KCl). Biophysical characterization of the native sequence and loop mutants suggests that the DNA adopts the same structure in solution and in crystalline form, and that loop interactions are important for the G4 stability but not for its folding. Four-tetrad G4 structures are sparse. Thus, our work advances understanding of the structural diversity of G-quadruplexes and yields coordinates for in silico drug screening programs and G4 predictive tools

    Stochastic mean-field dynamics for fermions in the weak coupling limit

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    Assuming that the effect of the residual interaction beyond mean-field is weak and has a short memory time, two approximate treatments of correlation in fermionic systems by means of Markovian quantum jump are presented. A simplified scenario for the introduction of fluctuations beyond mean-field is first presented. In this theory, part of the quantum correlations between the residual interaction and the one-body density matrix are neglected and jumps occur between many-body densities formed of pairs of states D=Φa><Φb/D=| \Phi_a > < \Phi_b |/ where Φa>| \Phi_a > and Φb>| \Phi_b > are antisymmetrized products of single-particle states. The underlying Stochastic Mean-Field (SMF) theory is discussed and applied to the monopole vibration of a spherical 40^{40}Ca nucleus under the influence of a statistical ensemble of two-body contact interaction. This framework is however too simplistic to account for both fluctuation and dissipation. In the second part of this work, an alternative quantum jump method is obtained without making the approximation on quantum correlations. Restricting to two particles-two holes residual interaction, the evolution of the one-body density matrix of a correlated system is transformed into a Lindblad equation. The associated dissipative dynamics can be simulated by quantum jumps between densities written as D=Φ>D = | \Phi > is a normalized Slater determinant. The associated stochastic Schroedinger equation for single-particle wave-functions is given.Comment: Enlarged version, 10 pages, 2 figure
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