2,230 research outputs found
Corporate Social Responsibility – The Global Financial Crisis: A Case Study on the Rise of Toyota and the Demise of General Motors
Globalisation has connected the world at a phenomenal rate (Becks, 2000), and because of globalisation, MNCs now have to play roles that were traditionally the responsibilities of governments. Also, with global warming issues on the rise, the role that auto manufacturing companies play in curbing greenhouse emission cannot be ignored. This article will compare the Corporate Social Responsibility (CSR) practices of General Motors with Toyota. In this „David versus Goliath‟ saga, Toyota overtook GM in 2008 to become the world‟s largest automaker. Why GM failed as an automaker could be attributed to their inability to fully operationalise their corporate social responsibility commitments and strategies. Toyota, on the other hand implemented their CSR strategies on a global scale. The article proposes that CSR is crucial in the auto industry, and great companies, such as GM, can and will fail if they ignore the importance of CSR.
Keywords: Corporate social responsibility, auto industry, Toyota, GM, Big Thre
Direct and quantitative absorptive spectroscopy of nanowires
Thesis (S.M.)--Massachusetts Institute of Technology, Dept. of Mechanical Engineering, 2012.Cataloged from PDF version of thesis.Includes bibliographical references (p. 125-130).Photonic nanostructures exhibit unique optical properties that are attractive in many different applications. However, measuring the optical properties of individual nanostructures, in particular the absorptive properties, remains a significant challenge. Conventional methods typically provide either an indirect or qualitative measure of absorption. The objective of this thesis is to therefore demonstrate a method capable of directly and quantitatively measuring the absorptive properties of individual nanostructures. This method is based on atomic force microscope (AFM) cantilever thermometry where a bimorph cantilever is used as a heat flux sensor. These sensors operate on the principle of a thermomechanical bending response and by virtue of their dimensionality, are capable of picowatt sensitivity. To validate the use of this technique, a single silicon nanowire is measured. By attaching a silicon nanowire to a cantilever and illuminating the sample with monochromatic light, the absolute absorptance spectrum of the nanowire was measured and shown to match well with theory. This spectroscopic technique can conceivably be used to measure even smaller samples, samples which cannot be characterized using conventional methods.by Jonathan Kien-Kwok Tong.S.M
Astrobatics: Characterization of Experimental Self-Toss Maneuvers at the Naval Postgraduate School and NASA Ames
Astrodynamics 2020, Advances in the Astronautical Sciences, Vol 175Astrobee is a small, compact vehicle designed to operate onboard the International Space Station and perform tasks related to observation, maintenance, and hosting guest science experiments. ASTROBATICS, is an experiment led by the Spacecraft Robotics Laboratory of the Naval Postgraduate School in collaboration with NASA. ASTROBATICS is investigating self-toss hopping maneuvers to be utilized within the International Space Station in order to provide a method of locomotion. As part of the preliminary preparation, experiments were conducted at the Naval Postgraduate School and NASA Ames in order to characterize self-toss maneuvers
Clinical and cost-effectiveness of internal limiting membrane peeling for patients with idiopathic full thickness macular hole. Protocol for a Randomised Controlled Trial : FILMS (Full-thickness macular hole and Internal Limiting Membrane peeling Study)
Background: A full-thickness macular hole (FTMH) is a common retinal condition associated with impaired vision. Randomised controlled trials (RCTs) have demonstrated that surgery, by means of pars plana vitrectomy and post-operative intraocular tamponade with gas, is effective for stage 2, 3 and 4 FTMH. Internal limiting membrane (ILM) peeling has been introduced as an additional surgical manoeuvre to increase the success of the surgery; i.e. increase rates of hole closure and visual improvement. However, little robust evidence exists supporting the superiority of ILM peeling compared with no-peeling techniques. The purpose of FILMS (Fullthickness macular hole and Internal Limiting Membrane peeling Study) is to determine whether ILM peeling improves the visual function, the anatomical closure of FTMH, and the quality of life of patients affected by this disorder, and the cost-effectiveness of the surgery.
Methods/Design: Patients with stage 2–3 idiopathic FTMH of less or equal than 18 months duration (based on symptoms reported by the participant) and with a visual acuity ≤ 20/40 in the study eye will be enrolled in this FILMS from eight sites across the UK and Ireland. Participants will be randomised to receive combined cataract surgery (phacoemulsification and intraocular lens implantation) and pars plana vitrectomy with postoperative intraocular tamponade with gas, with or without ILM peeling. The primary outcome is distance visual acuity at 6 months. Secondary outcomes include distance visual acuity at 3 and 24 months, near visual acuity at 3, 6, and 24 months, contrast sensitivity at 6 months, reading speed at 6 months, anatomical closure of the macular hole at each time point (1, 3, 6, and 24 months), health related quality of life (HRQOL) at six months, costs to the health service and the participant, incremental costs per quality adjusted life year (QALY) and adverse events.
Discussion: FILMS will provide high quality evidence on the role of ILM peeling in FTMH surgery.
Trial registration: This trial is registered with Current Controlled Trials ISRCTN number 33175422 and Clinical Trials.gov identifier NCT00286507.Chief Scientist Office, Scotland (project ref no CZH/4/235), NHS GrampianPeer reviewedPublisher PD
ENSO diversity shows robust decadal variations that must be captured for accurate future projections
El Niño-Southern Oscillation (ENSO) shows a large diversity of events that is modulated by climate variability and change. The representation of this diversity in climate models limits our ability to predict their impact on ecosystems and human livelihood. Here, we use multiple observational datasets to provide a probabilistic description of historical variations in event location and intensity, and to benchmark models, before examining future system trajectories. We find robust decadal variations in event intensities and locations in century-long observational datasets, which are associated with perturbations in equatorial wind-stress and thermocline depth, as well as extra-tropical anomalies in the North and South Pacific. Some climate models are capable of simulating such decadal variability in ENSO diversity, and the associated large-scale patterns. Projections of ENSO diversity in future climate change scenarios strongly depend on the magnitude of decadal variations, and the ability of climate models to reproduce them realistically over the 21st century
Prevalence and risk factors of community-associated methicillin-resistant carriage in Asia-Pacific region from 2000 to 2016:a systematic review and meta-analysis
Objective: Community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) is an emerging global public health threat. In response to a highlighted strategic priority of the World Health Organization Global Action Plan on Antimicrobial Resistance, to "strengthen the knowledge and evidence base through surveillance and research", we synthesized published articles to estimate CA-MRSA carriage prevalence in the Asia-Pacific region. Methods: A systematic review was conducted following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines (PROSPERO CRD:42017067399). We searched MEDLINE, EMBASE, and PubMed for articles published from 1 January 2000 to 19 May 2017, which reported CA-MRSA carriage (defined as either colonization or infection) in Asia-Pacific region from 2000 to 2016. Studies were stratified according to settings (community or hospital where CA-MRSA was isolated) and study populations (general public or subpopulations with specified characteristics). Ranges of CA-MRSA carriage prevalence were reported for study groups. Results: In total, 152 studies were identified. Large diversity was observed among studies in most study groups. In community-level studies, the CA-MRSA carriage prevalence among the general public ranged from 0% to 23.5%, whereas that ranged from 0.7% to 10.4% in hospital settings. From community-level studies, countries with the highest prevalence were India (16.5%-23.5%), followed by Vietnam (7.9%) and Taiwan (3.5%-3.8%). Children aged ≤6 (range: 0.5%-40.3%) and household members of CA-MRSA carriers (range: 13.0%-26.4%) are subgroups without specific health conditions but with much higher CA-MRSA carriage when compared to the general population. Conclusion: Our CA-MRSA prevalence estimates serve as the baseline for future national and international surveillance. The ranges of prevalence and characteristics associated with CA-MRSA carriage can inform health authorities to formulate infection control policies for high-risk subgroups. Future studies should explore the heterogeneities in CA-MRSA carriage prevalence among subgroups and countries to clarify the predominant transmission mechanisms in Asia-Pacific and other regions
Spatial inflection and memory for direction in Acazulco Otomi
Many languages have developed a specialized tool for coding spatial background aspects of events: associated motion morphology. This sparsely investigated verb inflection allows speakers to specify that the situation described by a verb takes place against the background of a motion event, as in “sing (while coming)”. Associated-motion systems typically include deictic information, and when verb inflection requires distinctions between motion in different directions, a thinking-for-speaking account would predict cognitive consequences in the shape of heightened memory for direction. To evaluate this hypothesis, we compare encoding of and memory for direction in an endangered Otopamean language, Acazulco Otomí (Mexico). First, we examine diversity and frequency in the use of associated-motion inflection in pilgrim narratives. Then, we investigate the potential cognitive correlates with a psycholinguistic recognition-memory experiment measuring change-detection performance. Linguistic encoding of background direction was found to support memory for direction, but the sample size was small, and the experiment further indicated that both the associated-motion inflection and its corresponding attention patterns are in a process of dissolution. This echoes findings in Arrernte and Mojeño Trinitario, and we discuss why associated motion might be an especially vulnerable category in language-endangerment contexts
Evening-types show highest increase of sleep and mental health problems during the COVID-19 pandemic - Multinational study on 19,267 adults
Study objectives: Individual circadian type is a ubiquitous trait defining sleep, with eveningness often associated with poorer sleep and mental health than morningness. However, it is unknown whether COVID-19 pandemic has differentially affected sleep and mental health depending on the circadian type. Here, the differences in sleep and mental health between circadian types are examined globally before and during the COVID-19 pandemic. Methods: The sample collected between May and August 2020 across 12 countries/regions consisted of 19,267 adults with information on their circadian type. Statistical analyses were performed by using Complex Sample procedures, stratified by country and weighted by the number of inhabitants in the country/area of interest and by the relative number of responders in that country/area. Results: Evening-types had poorer mental health, well-being, and quality of life or health than other circadian types during the pandemic. Sleep-wake schedules were delayed especially on working days, and evening-types reported an increase in sleep duration. Sleep problems increased in all circadian types, but especially among evening-types, moderated by financial suffering and confinement. Intermediate-types were less vulnerable to sleep changes, although morningness protected from most sleep problems. These findings were confirmed after adjusting for age, sex, duration of the confinement or socio-economic status during the pandemic. Conclusions: These findings indicate an alarming increase in sleep and mental health problems, especially among evening-types as compared to other circadian types during the pandemic. Keywords: Chronotype; Circadian Rhythms; Coronavirus; Depression; Eveningness; Insomnia; Sleep quality; Stress.Peer reviewe
Transplantation of canine olfactory ensheathing cells producing chondroitinase ABC promotes chondroitin sulphate proteoglycan digestion and axonal sprouting following spinal cord injury
Olfactory ensheathing cell (OEC) transplantation is a promising strategy for treating spinal cord injury (SCI), as has been demonstrated in experimental SCI models and naturally occurring SCI in dogs. However, the presence of chondroitin sulphate proteoglycans within the extracellular matrix of the glial scar can inhibit efficient axonal repair and limit the therapeutic potential of OECs. Here we have used lentiviral vectors to genetically modify canine OECs to continuously deliver mammalian chondroitinase ABC at the lesion site in order to degrade the inhibitory chondroitin sulphate proteoglycans in a rodent model of spinal cord injury. We demonstrate that these chondroitinase producing canine OECs survived at 4 weeks following transplantation into the spinal cord lesion and effectively digested chondroitin sulphate proteoglycans at the site of injury. There was evidence of sprouting within the corticospinal tract rostral to the lesion and an increase in the number of corticospinal axons caudal to the lesion, suggestive of axonal regeneration. Our results indicate that delivery of the chondroitinase enzyme can be achieved with the genetically modified OECs to increase axon growth following SCI. The combination of these two promising approaches is a potential strategy for promoting neural regeneration following SCI in veterinary practice and human patients
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